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E-grāmata: Harpers Illustrated Biochemistry 30th Edition

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  • Formāts: 832 pages
  • Izdošanas datums: 22-Mar-2015
  • Izdevniecība: McGraw-Hill Professional
  • Valoda: eng
  • ISBN-13: 9780071825375
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  • Formāts: 832 pages
  • Izdošanas datums: 22-Mar-2015
  • Izdevniecība: McGraw-Hill Professional
  • Valoda: eng
  • ISBN-13: 9780071825375
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Gain a thorough understanding of the principles ofbiochemistry as they relate to the study of clinical medicineA Doody's Core Title for 2017!

THE BEST REVIEW FOR THE USMLE!

The Thirtieth Edition of Harpers Illustrated Biochemistry combines outstanding full-colorillustrations with authoritative integrated coverage of biochemical disease and clinical information. Using brevity and numerous medically relevant examples, Harper's presents a clear, succinct review of the fundamentals of biochemistry that every student must understand in order to succeed in medical school.

All fifty-eight chapters emphasize the medical relevance of biochemistry





Full-color presentation includes more than 600 illustrations Each chapter includes a section on BiomedicalImportance and a summary of the topics covered Review questions follow each of the eleven sections Case studies in every chapter emphasize the clinical relevance to biochemistry NEW coverage of toxic naturally-occurring amino acids; extraterrestrial biomolecules; computer-aided drug design; the role of complement cascade in bacterial and viral infection; secreted mediators of cell-cell signaling between leukocytes; the role of mast cells, basophils, andeosinophils; and the hazard of antioxidants that down-regulate radical signaling for apoptosis and increase risk of cancer





Applauded by medical students for its current and engaging style, Harper's Illustrated Biochemistry is an essential for USMLE review and the single best reference for learning the clinical relevance of any biochemistry topic.
Preface xi
SECTION I Structures & Functions of Proteins & Enzymes
1(50)
1 Biochemistry & Medicine
1(5)
Victor W. Rodwell
Robert K. Murray
2 Water & pH
6(9)
Peter J. Kennelly
Victor W. Rodwell
3 Amino Acids & Peptides
15(10)
Peter J. Kennelly
Victor W. Rodwell
4 Proteins: Determination of Primary Structure
25(11)
Peter J. Kennelly
Victor W. Rodwell
5 Proteins: Higher Orders of Structure
36(15)
Peter J. Kennelly
Victor W. Rodwell
SECTION II Enzymes: Kinetics, Mechanism, Regulation, & Bioinformatics
51(62)
6 Proteins: Myoglobin & Hemoglobin
51(9)
Peter J. Kennelly
Victor W. Rodwell
7 Enzymes: Mechanism of Action
60(13)
Peter J. Kennelly
Victor W. Rodwell
8 Enzymes: Kinetics
73(14)
Peter J. Kennelly
Victor W. Rodwell
9 Enzymes: Regulation of Activities
87(10)
Peter J. Kennelly
Victor W. Rodwell
10 Bioinformatics & Computational Biology
97(16)
Peter J. Kennelly
Victor W. Rodwell
SECTION III Bioenergetics
113(26)
11 Bioenergetics: The Role of ATP
113(6)
Kathleen M. Botham
Peter A. Mayes
12 Biologic Oxidation
119(7)
Kathleen M. Botham
Peter A. Mayes
13 The Respiratory Chain & Oxidative Phosphorylation
126(13)
Kathleen M. Botham
Peter A. Mayes
SECTION IV Metabolism of Carbohydrates
139(72)
14 Overview of Metabolism & the Provision of Metabolic Fuels
139(13)
David A. Bender
Peter A. Mayes
15 Carbohydrates of Physiological Significance
152(9)
David A. Bender
Peter A. Mayes
16 The Citric Acid Cycle: The Central Pathway of Carbohydrate, Lipid & Amino Acid Metabolism
161(7)
David A. Bender
Peter A. Mayes
17 Glycolysis & the Oxidation of Pyruvate
168(8)
David A. Bender
Peter A. Mayes
18 Metabolism of Glycogen
176(9)
David A. Bender
Peter A. Mayes
19 Gluconeogenesis & the Control of Blood Glucose
185(11)
David A. Bender
Peter A. Mayes
20 The Pentose Phosphate Pathway & Other Pathways of Hexose Metabolism
196(15)
David A. Bender
Peter A. Mayes
SECTION V Metabolism of Lipids
211(70)
21 Lipids of Physiologic Significance
211(12)
Kathleen M. Botham
Peter A. Mayes
22 Oxidation of Fatty Acids: Ketogenesis
223(9)
Kathleen M. Botham
Peter A. Mayes
23 Biosynthesis of Fatty Acids & Eicosanoids
232(13)
Kathleen M. Botham
Peter A. Mayes
24 Metabolism of Acylglycerols & Sphingolipids
245(8)
Kathleen M. Botham
Peter A. Mayes
25 Lipid Transport & Storage
253(13)
Kathleen M. Botham
Peter A. Mayes
26 Cholesterol Synthesis, Transport, & Excretion
266(15)
Kathleen M. Botham
Peter A. Mayes
SECTION VI Metabolism of Proteins & Amino Acids
281(58)
27 Biosynthesis of the Nutritionally Nonessential Amino Acids
281(6)
Victor W. Rodwell
28 Catabolism of Proteins & of Amino Acid Nitrogen
287(10)
Victor W. Rodwell
29 Catabolism of the Carbon Skeletons of Amino Acids
297(16)
Victor W. Rodwell
30 Conversion of Amino Acids to Specialized Products
313(10)
Victor W. Rodwell
31 Porphyrins & Bile Pigments
323(16)
Victor W. Rodwell
Robert K. Murray
SECTION VII Structure, Function, & Replication of Informational Macromolecules
339(138)
32 Nucleotides
339(8)
Victor W. Rodwell
33 Metabolism of Purine & Pyrimidine Nucleotides
347(12)
Victor W. Rodwell
34 Nucleic Acid Structures Function
359(11)
P. Anthony Weil
35 DNA Organization, Replication, & Repair
370(24)
P. Anthony Weil
36 RNA Synthesis, Processing, & Modification
394(19)
P. Anthony Weil
37 Protein Synthesis & the Genetic Code
413(15)
P. Anthony Weil
38 Regulation of Gene Expression
428(23)
P. Anthony Weil
39 Molecular Genetics, Recombinant DNA, & Genomic Technology
451(26)
P. Anthony Weil
SECTION VIII Biochemistry of Extracellular & Intracellular Communication
477(60)
40 Membranes: Structure & Function
477(21)
Robert K. Murray
P. Anthony Weil
41 The Diversity of the Endocrine System
498(20)
P. Anthony Weil
42 Hormone Action & Signal Transduction
518(19)
P. Anthony Weil
43 Nutrition, Digestion, & Absorption
537(1)
David A. Bender
Peter A. Mayes
SECTION IX Special Topics (A)
537(70)
44 Micronutrients: Vitamins & Minerals
546(18)
David A. Bender
45 Free Radicals & Antioxidant Nutrients
564(5)
David A. Bender
56 Glycoproteins
569(14)
David A. Bender
Robert K. Murray
47 Metabolism of Xenobiotics
583(6)
David A. Bender
Robert K. Murray
48 Clinical Biochemistry
589(18)
David A. Bender
Joe Varghese
Molly Jacob
Robert K. Murray
SECTION X Special Topics (B)
607(104)
49 Intracellular Traffic & Sorting of Proteins
607(20)
Kathleen M. Botham
Robert K. Murray
50 The Extracellular Matrix
627(20)
Kathleen M. Botham
Robert K. Murray
51 Muscle & the Cytoskeleton
647(21)
Peter J. Kennelly
Robert K. Murray
52 Plasma Proteins & Immunoglobulins
668(21)
Peter J. Kennelly
Robert K. Murray
Molly Jacob
Joe Varghese
53 Red Blood Cells
689(11)
Peter J. Kennelly
Robert K. Murray
54 White Blood Cells
700(11)
Peter J. Kennelly
Robert K. Murray
SECTION XI Special Topics (C)
711(60)
55 Hemostasis & Thrombosis
711(11)
Peter L. Gross
Robert K. Murray
P. Anthony Weil
Margaret L. Rand
56 Cancer: An Overview
722(24)
Molly Jacob
Joe Varghese
Robert K. Murray
P. Anthony Weil
57 Biochemical Case Histories
746(9)
David A. Bender
58 The Biochemistry of Aging
755(16)
Peter J. Kennelly
The Answer Bank 771(6)
Index 777
Robert K. Murray, MD, PhD Professor (Emeritus) of Biochemistry University of Toronto Toronto, Ontario Daryl K. Granner, MD Joe C. Davis Professor of Biomedical Science Director, Vanderbilt Diabetes Center Professor of Molecular Physiology and Biophysics and of Medicine Vanderbilt University Nashville, Tennessee Peter A. Mayes, PhD, DSc Emeritus Professor of Veterinary Biochemistry Royal Veterinary College University of London London Victor W. Rodwell, PhD Professor of Biochemistry Purdue University West Lafayette, Indiana