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Heat Transfer and Fluid Flow in Biological Processes [Hardback]

Edited by (Associate Professor, Department of Mechanical Engineering, University of Canterbury, Christchurch, New Zealand), Edited by (Professor, Department of Mechanical and Aerospace Engineering, North Carolina State University, NC, USA)
  • Formāts: Hardback, 428 pages, height x width: 235x191 mm, weight: 1040 g, 65 illustrations (50 in full color); Illustrations, unspecified
  • Izdošanas datums: 06-Jan-2015
  • Izdevniecība: Academic Press Inc
  • ISBN-10: 0124080774
  • ISBN-13: 9780124080775
  • Hardback
  • Cena: 115,84 €
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  • Formāts: Hardback, 428 pages, height x width: 235x191 mm, weight: 1040 g, 65 illustrations (50 in full color); Illustrations, unspecified
  • Izdošanas datums: 06-Jan-2015
  • Izdevniecība: Academic Press Inc
  • ISBN-10: 0124080774
  • ISBN-13: 9780124080775

Heat Transfer and Fluid Flow in Biological Processes covers emerging areas in fluid flow and heat transfer relevant to biosystems and medical technology. This book uses an interdisciplinary approach to provide a comprehensive prospective on biofluid mechanics and heat transfer advances and includes reviews of the most recent methods in modeling of flows in biological media, such as CFD. Written by internationally recognized researchers in the field, each chapter provides a strong introductory section that is useful to both readers currently in the field and readers interested in learning more about these areas.

Heat Transfer and Fluid Flow in Biological Processes is an indispensable reference for professors, graduate students, professionals, and clinical researchers in the fields of biology, biomedical engineering, chemistry and medicine working on applications of fluid flow, heat transfer, and transport phenomena in biomedical technology.

  • Provides a wide range of biological and clinical applications of fluid flow and heat transfer in biomedical technology
  • Covers topics such as electrokinetic transport, electroporation of cells and tissue dialysis, inert solute transport (insulin), thermal ablation of cancerous tissue, respiratory therapies, and associated medical technologies
  • Reviews the most recent advances in modeling techniques

Papildus informācija

A must-have compendium of the most current research and advances in heat transfer and fluid flow in biological systems and biomedical technology
Contributors ix
Preface xi
1 Bioheat Transfer and Thermal Heating for Tumor Treatment
Huang-Wen Huang
Tzyy-Leng Horng
1.1 Pennes' and Other Bioheat Transfer Equations
1(4)
1.2 Blood Flow Impacts on Thermal Lesions with Pulsation and Different Velocity Profiles
5(10)
1.3 Thermal Relaxation Time Factor in Blood Flow During Thermal Therapy
15(9)
1.4 PBHTE with the Vascular Cooling Network Model
24(5)
1.5 Hyperthermia Treatment Planning
29(11)
References
40(3)
2 Tissue Response to Short Pulse Laser Irradiation
Mohit Ganguly
Ryan O'Flaherty
Amir Sajjadi
Kunal Mitra
2.1 Introduction
43(3)
2.2 Mathematical Formulation
46(4)
2.3 Experimental Methods
50(1)
2.4 Results and Discussion
51(5)
2.5 Conclusion
56(1)
References
57(2)
3 Quantitative Models of Thermal Damage to Cells and Tissues
Neil T. Wright
3.1 Introduction
59(1)
3.2 Heat Transfer in Tissue
60(1)
3.3 Reaction Rates and Temperature
61(2)
3.4 Thermal Denaturation of Proteins
63(3)
3.5 Cells
66(3)
3.6 Tissue-Level Descriptions
69(3)
3.7 Discussion
72(1)
References
73(5)
4 Analytical Bioheat Transfer: Solution Development of the Pennes' Model
Sid M. Becker
4.1 Pennes' Bioheat Equation in Living Tissue Analogy
78(4)
4.2 Solutions to the Transient Homogenous Bioheat Equation
82(13)
4.3 Solution Approaches to Nonhomogenous Problems
95(12)
4.4 Additional Considerations
107(1)
4.5 The Composite Bioheat Problem
108(15)
4.6 Summary Remarks
123(1)
References
124(1)
5 Characterizing Respiratory Airflow and Aerosol Condensational Growth in Children and Adults Using an Imaging-CFD Approach
Jinxiang Xi
Xiuhua A. Si
Jong Won Kim
5.1 Introduction
125(2)
5.2 Methods
127(7)
5.3 Results
134(14)
5.4 Discussion
148(3)
5.5 Conclusion
151(1)
References
152(5)
6 Transport in the Microbiome
R.J. Clarke
6.1 Introduction
157(1)
6.2 The Human Microbiome
158(2)
6.3 Swimming Microorganisms
160(19)
6.4 Continuum Descriptions
179(5)
6.5 Discussion
184(1)
References
185(5)
7 A Critical Review of Experimental and Modeling Research on the Leftward Flow Leading to Left-Right Symmetry Breaking in the Embryonic Node
I.A. Kuznetsov
A.V. Kuznetsov
7.1 Introduction
190(1)
7.2 Experimental Research on the Leftward Nodal Flow and LR Symmetry Breaking
191(2)
7.3 Modeling Research on the Nodal Flow
193(1)
7.4 Leftward Flow or Flow Recirculation?
194(1)
7.5 Sensing of the Flow: Mechanosensing or Chemosensing?
194(2)
7.6 Modeling the Effect of a Ciliated Surface by Imposing a Given Vorticity at the Edge of the Ciliated Layer
196(4)
7.7 Summary of Relevant Parameters Describing the Nodal Flow and Estimates of Their Values
200(1)
7.8 Numerical Results Obtained Assuming a Constant Vorticity at the Edge of the Ciliated Layer
201(2)
7.9 Conclusions
203(1)
Acknowledgments
204(1)
References
204(3)
8 Fluid-Biofilm Interactions in Porous Media
George E. Kapellos
Terpsichori S. Alexiou
Stavros Pavlou
8.1 Microbial Biofilms in Porous Media
207(9)
8.2 A Motivating Problem: Biofilms and the Fate of Contaminants in Soil
216(2)
8.3 Models of Biofilm Growth and Pattern Formation in Quiescent Fluids
218(4)
8.4 Computational Simulation of Fluid-Biofilm Interactions in Porous Media
222(5)
8.5 Mechanisms of Biological Clogging in Porous Media
227(7)
8.6 Summary
234(1)
References
234(5)
9 Flow Through a Permeable Tube
C. Pozrikidis
9.1 Introduction
239(1)
9.2 Axisymmetric Stokes Flow
240(5)
9.3 Flow Through an Infinite Permeable Tube
245(7)
9.4 Starling's Equation
252(5)
9.5 Flow Through a Tube with Finite Length
257(9)
9.6 Effect of Wall Slip
266(6)
9.7 Summary
272(1)
References
272(2)
10 Transdermal Drug Delivery and Percutaneous Absorption: Mathematical Modeling Perspectives
Filippo De Monte
Giuseppe Pontrelli
Sid M. Becker
10.1 Introduction
274(2)
10.2 Physiological Description and Drug Transport Models
276(10)
10.3 Review of Mathematical Methods
286(2)
10.4 Modeling TDD Through a Two-Layered System
288(12)
10.5 Conclusions
300(2)
References
302(3)
11 Mechanical Stress Induced Blood Trauma
Katharine Fraser
11.1 Introduction
305(1)
11.2 Mechanical Stresses Experienced by Blood
306(4)
11.3 Fluid Dynamic Effects on Blood Constituents
310(11)
11.4 Numerical Models of Damage to the Blood Constituents
321(7)
11.5 Summary
328(1)
References
329(7)
12 Modeling of Blood Flow in Stented Coronary Arteries
Claudio Chiastra
Francesco Migliavacca
12.1 Introduction
336(2)
12.2 Hemodynamic Quantities of Interest
338(4)
12.3 Fluid Dynamic Models of Idealized Stented Geometries
342(10)
12.4 Fluid Dynamic Models of Image-Based Stented Geometries
352(10)
12.5 Limitations of the Current CFD Models and Future Remarks
362(3)
12.6 Conclusions
365(1)
Acknowledgments
366(1)
References
366(5)
13 Hemodynamics in the Developing Cardiovascular System
C. Poelma
B.P. Hierck
13.1 Introduction
371(1)
13.2 The Chicken Embryo Model System
372(2)
13.3 Relevant Fluid Mechanic Regimes
374(8)
13.4 Experimental Studies
382(10)
13.5 Mechanotransduction
392(4)
13.6 Hemorheology
396(4)
13.7 Conclusions and Outlook
400(1)
References
401(6)
Index 407
Sid Becker is an Associate Professor in the Department of Mechanical Engineering at the University of Canterbury. He is an Alexander von Humboldt Fellow and is a recipient of the Royal Society of New Zealand Marsden Grant. He has held academic positions in Germany, the United States, and New Zealand. His research is primarily in computational and analytical modelling of heat and mass transfer processes in biological media. Dr. Becker is also the editor of the book Modeling of Microscale Transport in Biological Processes (2017) and co-editor of the books Heat Transfer and Fluid Flow in Biological Processes (2015), and Transport in Biological Media (2013). Dr. Kuznetsov is Professor at the Department of Mechanical & Aerospace Engineering at North Carolina State University. He holds a joint professorial position at the University of North Carolinas Biomedical Engineering Department. He is a Fellow of American Society of Mechanical Engineering, an Editorial Board Member of the Proceeding of the Royal Society A, and an Associate Editor of the Journal of Porous Media. He is a recipient of the prestigious Humboldt Research Award. In 2014, Dr. Kuznetsov was elected as a Member of the Scientific Council of the International Center of Heat and Mass Transfer. He has published more than 400 journal papers, 17 book chapters, 3 books, and 100 conference papers. His works have been cited over 12,000 times: he has an h-index of 51 and an i-10 index of over 220. While his most notable early contributions are in the development of the field of porous media, Prof. Kuznetsovs research interests in the general area of numerical modeling are extensive, including transport in living tissues, sub-cellular transport, mass transport in neurons and axons, bioheat transport, bioconvective sedimentation, fluid mechanics, flows in microgravity, and turbulence.