Atjaunināt sīkdatņu piekrišanu

Hematopoietic Stem Cell Transplantation and Cellular Therapies for Autoimmune Diseases [Hardback]

Edited by (Careggi University Hospital, Italy), Edited by (Northwestern University, USA), Edited by (Sheffield Teaching Hospitals, UK), Edited by (Univeristy of Paris, France), Edited by (University of Sćo Paulo, Brazil)
  • Formāts: Hardback, 666 pages, height x width: 280x210 mm, weight: 2081 g, 28 Tables, color; 198 Tables, black and white; 116 Line drawings, color; 16 Line drawings, black and white; 56 Halftones, color; 13 Halftones, black and white; 172 Illustrations, color; 29 Illustrations, black and white
  • Izdošanas datums: 18-Nov-2021
  • Izdevniecība: CRC Press
  • ISBN-10: 1138558559
  • ISBN-13: 9781138558557
Citas grāmatas par šo tēmu:
  • Hardback
  • Cena: 115,40 €*
  • * ši ir gala cena, t.i., netiek piemērotas nekādas papildus atlaides
  • Standarta cena: 215,59 €
  • Ietaupiet 46%
  • Grāmatu piegādes laiks ir 3-4 nedēļas, ja grāmata ir uz vietas izdevniecības noliktavā. Ja izdevējam nepieciešams publicēt jaunu tirāžu, grāmatas piegāde var aizkavēties.
  • Daudzums:
  • Ielikt grozā
  • Piegādes laiks - 4-6 nedēļas
  • Pievienot vēlmju sarakstam
  • Formāts: Hardback, 666 pages, height x width: 280x210 mm, weight: 2081 g, 28 Tables, color; 198 Tables, black and white; 116 Line drawings, color; 16 Line drawings, black and white; 56 Halftones, color; 13 Halftones, black and white; 172 Illustrations, color; 29 Illustrations, black and white
  • Izdošanas datums: 18-Nov-2021
  • Izdevniecība: CRC Press
  • ISBN-10: 1138558559
  • ISBN-13: 9781138558557
Citas grāmatas par šo tēmu:
This book summarizes the global progress in medical and scientific research toward converting traditionally chronic autoimmune diseases into a drug-free reversible illness using hematopoietic stem cell transplantation (HSCT) and other cellular therapies such as T regulatory cells (Treg), mesenchymal stromal/stem cells, and chimeric antigen receptor T (CAR T) cells in order to reintroduce sustained immune tolerance. This title provides information on different types of stem cells and immune cells; post-transplant immune regeneration; cellular regulatory requirements; ethical and economic considerations; and the advantages and disadvantages of HSCT in the treatment of a variety of autoimmune diseases versus current conventional treatments. Arranged by disease, the text provides a comprehensive guide to HSCT for all types of autoimmune/immune disorders including monogenetic autoimmune diseases; autoimmune aplastic anemia; neurologic immune diseases including multiple sclerosis, chronic inflammatory demyelinating polyneuropathy, neuromyelitis optica, and stiff person syndrome; rheumatologic diseases such as systemic sclerosis and systemic lupus erythematosus; dermatologic diseases such as pemphigus; gastrointestinal disorders such as Crohns disease and celiac disease; and immune-mediated endocrinologic disease type I diabetes mellitus. Guidance is provided on the transplantation technique, cell collection and processing, conditioning regimens, infections, and early and late complications.

Key Features











Outlines therapies and techniques for HSCT for autoimmune diseases





Discusses the advantages of HSCT over conventional therapies





Reviews the entire process of stem cell therapy from harvest and ethics to indications, efficacy, and regulatory oversight

Recenzijas

"Over the past 25 years, the utilization of hematopoietic stem cell transplantation (HSCT) specifically for the treatment of autoimmune diseases has gradually evolved from an initial state of salvage therapy for severely affected patients towards a standard procedure for selected patients in the major indications multiple sclerosis (MS) and systemic sclerosis (SSc). The recently published book entitled Hematopoietic Stem Cell Transplantation and Cellular Therapies for Autoimmune Diseases now summarizes all recent developments and achievements in the area and provides the evidence and state-of-the-art of HSCT and emerging cellular therapies. The selected topics comprehensively highlight all relevant aspects of the procedures. The book was developed under the direction of Richard Burt from the Northwestern University, Chicago, one of pioneers and most eminent leaders in the field, in collaboration with the co-editors Dominique Farge, Milton A Ruiz, Riccardo Saccardi and John A Snowden. The book will attract a broad readership, particularly clinical scientists, clinicians and fellows dedicated to HSCT, both from a hematologic or autoimmune disease perspective.

Overall, this book summarizes all relevant milestones in the field, extensively covering HSCT and cellular therapies in ADs, a field characterized by ongoing progress. It reflects on the dramatic developments and achievements of cellular therapies in recent years, along the dynamics of modern biologic and targeted therapies for ADs. The book is a valuable reading, serving as an ideal manual of good practices for hematologists, disease specialists, as well as researchers and young physicians. Finally, the book acknowledges the contributions and efforts of individual experts and personalities, first and foremost Richard Burt, all the co-editors and the authors of the book, to whom we bow for this work."

- Tobias Alexander and Raffaella Greco and on behalf of the European Society for Blood and Marrow Transplantation (EBMT) Autoimmune Diseases Working Party (ADWP)

- Tobias Alexander, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Rheumatology and Clinical Immunology, Berlin, Germany.

- Raffaella Greco, Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

"This is a comprehensive collection of current knowledge on hematopoietic stem cell transplantation therapy for immune diseases. With 140 international experts in the field, this book serves as a valuable resource for those who practice and research in the field of transplantation and those who use such knowledge to care for their patients."

- Massoud Mahmoudi, DO, PhD, University of California San Francisco

Foreword ix
Preface xi
Acknowledgments xii
About the Editors xiii
List of Contributors
xv
SECTION I BIOLOGY OF IMMUNE CELLS
1 B Cells in Aging, Age-Associated Diseases and Stem Cell Transplantation
1(9)
Daniela Frasca
Maria Romero
2 T Cell Biology: Changes with Disease, Aging, and Hematopoietic Stem Cell Transplantation
10(9)
Valquiria Bueno
3 Plasma Cells in Autoimmunity
19(7)
Falk Hiepe
Alexander Tobias
Andreas Radbruch
4 Car T Cells for Autoimmunity
26(7)
Michael C. Milone
5 Regulatory T Cells for the Treatment of Autoimmune Diseases
33(14)
Claudia Selck
Margarita Dominguez-Villar
6 Mesenchymal Stromal Cell-Derived Extracellular Vesicles
47(11)
Ines Colmegna
Janusz Rak
SECTION II BIOLOGY OF STEM CELLS
7 Induced Pluripotent Stem Cells: The Story of Genetic Reprogramming
58(11)
Richard K. Burt
8 Mesenchymal Stromal Cell Biology and Clinical Application
69(9)
Siverine Loisel
Karin Tarte Pharm
9 Neural Stem Cell Biology
78(8)
Angela Genchi
Beatrice von Wunster
Paola Panina-Bordignon
Gianvito Martino
10 Hematopoietic Stem Cells: Hierarchical versus Continuum
86(6)
Peter Quesenberry
Sicheng Wen
Laura Goldberg
Mark Dooner
11 Biology of Umbilical Cord Blood Cells
92(10)
Gesine Kogler
Stefanie Liedtke
SECTION III REGULATORY REQUIREMENTS
12 Quality, Accreditation, and Regulation in Hematopoietic Stem Cell Transplantation
102(8)
Eoin McGrath
Joseph Schwartz
Phyllis I. Warkentin
Riccardo Saccardi
John A. Snowden
13 European Perspective on Cellular Therapy: Good Tissue Practice (GTP) versus Good Manufacturing Practice (GMP)
110(7)
Elodie Kerjean
Bechara Mfarrej
Christian Chabannon
14 GMP Facility Requirements in the United States
117(5)
Cheryl Stratton
Ann LeFever
SECTION IV MESENCHYMAL STEM CELLS FOR IMMUNE DISEASES
15 Mesenchymal Stromal Cell Therapy for Acute Graft versus Host Disease---From Bench to Clinical Approval
122(8)
Erik Boberg
Katarina Le Blanc
16 Adipose-Derived Stem Cells for Systemic Sclerosis Digital Ulcers
130(8)
Nicoletta Del Papa
Antonina Minniti
Francesca Pignataro
Wanda Maglione
Dominique Farge
Roberto F. Caporali
17 Musculoskeletal Stromal/Progenitor Cell-Based Cell Therapy for Rheumatoid Arthritis (RA): MSC for Cell Therapy in R A
138(9)
Yves-Marie Pers
Dominique Farge
Christian Jorgensen
18 Mesenchymal Stromal Cells for Systemic Sclerosis
147(7)
Dominique Farge
19 Mesenchymal Stem Cells (MSC) for Systemic Lupus Erythematosus (SLE)
154(9)
Lingyun Sun
Xinran Yuan
20 Mesenchymal Stem/Stromal Cells for Multiple Sclerosis and Other Neurological Diseases
163(8)
Antonio Uccelli
Tiziana Vigo
Alice Laroni
21 Mesenchymal Stromal Cells for Perianal Fistulizing Crohn's Disease
171(11)
Antonio Giordano
Julian Panes
22 Umbilical Cord Blood or Mesenchymal Stromal Cells as Potential Therapies for Autism Spectrum Disorder
182(7)
Jessica M. Sun
Joanne Kurtzberg
SECTION V GENERAL CONCEPTS-HSCT FOR AUTOIMMUNE DISEASES
23 Animal Models of Bone Marrow Transplantation for Autoimmune Diseases
189(15)
Yasushi Adachi
Ming Li
Richard K. Burt
Naoki Hosaka
Susumu Ikehara
24 Autologous HSCT Conditioning Regimens for Autoimmune Diseases
204(9)
Richard K. Burt
Dominique Farge
Riccardo Saccardi
Kathleen Quigley
Xiaoqiang Han
John A. Snowden
25 Immune Reconstitution after Hematopoietic Stem Cell Transplantation in Autoimmune Disease
213(9)
Paolo A. Muraro
Maria T. Cencioni
26 Microbiota and Immune Response
222(7)
Ernst Holler
Hendrik Poeck
Daniela Weber
27 Infectious Complications in Patients Undergoing HSCT for Autoimmune Diseases
229(12)
Richard K. Burt
Dominique Farge
28 Early Toxicity and Supportive Care of HSCT for Autoimmune Diseases
241(11)
John A. Snowden
Azza Ismail
Richard K. Burt
Helen Jessop
29 Late Toxicity and Supportive Care of Patients Undergoing Hematopoietic Cell Transplantation for Autoimmune Diseases
252(12)
Nina Salooja
Richard K. Burt
John A. Snowden
30 Transfusion Medicine
264(7)
Khaled El-Ghariani
31 International Registries Sites/Indications/Activity for HSCT in Autoimmune Diseases: The European Society for Blood and Marrow Transplantation (EBMT) and Center for International Blood and Marrow Transplant Research (CIBMTR)
271(11)
John A. Snowden
Raffaella Greco
Manuela Badoglio
Myriam Labopin
Omar F. Davila Alvelo
Marcelo C. Pasquini
32 Hematopoietic Stem Cell Mobilization, Collection, Apheresis, Harvest Procedures
282(10)
Emilian Snarski
Richard K. Burt
SECTION VI ALLOGENEIC HSCT FOR AUTOIMMUNE DISEASE
33 Hematopoietic Stem Cell Donor Registries: Search Strategies and HLA Methodologies
292(8)
C. Stavropoulos
V. Gkioka
D. Charron
34 Allogeneic HSCT and Graft versus Host Disease (GvHD): General Principles with Reference to Autoimmune Diseases
300(10)
Jose Ros-Soto
Richard K. Burt
John A. Snowden
35 Hematopoietic Cell Transplantation in Monogenic Autoimmune Diseases
310(16)
S.H. Lum
E.P. Buddingh
M.A. Slatter
A.C. Lankester
36 Advances in the Pathogenesis and Treatment of Immune-Mediated Aplastic Anemia
326(9)
Shinji Nakao
Sabrina Giammarco
Andrea Bacigalupo
SECTION VII HSCT FOR AUTOIMMUNE DISEASE
37 Magnetic Resonance Imaging in Multiple Sclerosis
335(9)
Flavia Nelson
38 Multiple Sclerosis
344(11)
Azza Ismail
Richard K. Burt
Joachim Burman
Basil Sharrack
39 Disease-Modifying Therapies and Supportive Care of Multiple Sclerosis
355(14)
Edith Graham
Eileah Loda
Roumen Balabanov
40 Autologous Hematopoietic Stem Cell Transplantation for Secondary Progressive Multiple Sclerosis
369(6)
Richard K. Burt
Basil Sharrack
Roumen Balabanov
John Rose
Xiaoqiang Han
Kathleen Quigley
Riccardo Saccardi
41 Autologous Hematopoietic Stem Cell Transplantation for Relapsing-Remitting Multiple Sclerosis
375(11)
Richard K. Burt
Basil Sharrack
Joachim Burman
Flavia Nelson
John Rose
Xiaoqiang Han
Kathleen Quigley
Riccardo Saccardi
42 Immune Mechanisms of Autologous Hematopoietic Stem Cell Transplantation for Multiple Sclerosis
386(5)
Joachim Burman
43 Chronic Inflammatory Demyelinating Polyradiculoneuropathy: Basics and Interpretation of Electrodiagnostic Testing
391(8)
Hamza Malek
44 Diagnosis and Differentiation of CIDP from Other Peripheral Polyneuropathies
399(7)
Celine Labeyrie
Fanny Urbain
Cristina Castilla Llorente
45 Hematopoietic Stem Cell Transplantation for Chronic Inflammatory Demyelinating Polyradiculoneuropathy
406(11)
Gavin Brittain
Richard K. Burt
Basil Sharrack
46 Neuromyelitis Optica: Autologous and Allogeneic HSCT for AQP4-IgG-Positive Neuromyelitis Optica Spectrum Disorders
417(10)
Raffaella Greco
Shailee Shah
Sean J. Pittock
Richard K. Burt
47 Systemic Sclerosis
427(15)
Katja Lakota
Katja Perdan Pirkmajer
John Varga
48 The Systemic Sclerosis Heart
442(14)
Sanjiv J. Shah
49 Scleroderma Renal Crisis with Special Considerations for Autologous Hematopoietic Stem Cell Transplant
456(7)
Marie Hudson
Harold L. Atkins
Cybele Ghossein
50 Systemic Sclerosis and the Lung
463(16)
David G. Kiely
Robin Condliffe
51 Autologous Hematopoietic Stem Cell Transplantation in Systemic Sclerosis
479(10)
Dominique Farge
Zora Marjanovic
Richard K. Burt
52 Crohn's Disease: Incidence, Diagnosis, Standard Treatment, Prognosis, Outcome Measures
489(9)
Gabriel Marcellier
Xavier Treton
53 Hematopoietic Stem Cell Transplantation an Alternative to Treat Crohn's Disease
498(11)
Milton Artur Ruiz
Montserrat Rovira
Chris Hawkey
Elena Ricart
Roberto Luiz Kaiser Junior
Richard K. Burt
54 Type 1 Diabetes Mellitus: Hematopoietic Stem Cell Transplantation for Type 1 Diabetes Mellitus
509(9)
Carlos Eduardo Couri
Maria Carolina Oliveira
55 Systemic Lupus Erythematosus: Hematopoietic Stem Cell Transplantation for Systemic Lupus Erythematosus (SLE)
518(8)
Tobias Alexander
Renate Arnold
Falk Hiepe
Richard K. Burt
SECTION VIII HSCT FOR AUTOIMMUNE DISEASE---DEVELOPING INDICATIONS
56 Refractory Celiac Disease: Hematopoietic Stem Cell Transplantation for Refractory Celiac Disease Type II
526(9)
Abdulbaqi Al-Toma
57 Hematopoietic Stem Cell Transplantation for Juvenile Idiopathic Arthritis
535(12)
Mario Abinun
Su Han Lum
Arina Lazareva
Paul Veys
Mary A. Slatter
58 Hematopoietic Stem Cell Transplantation for Rheumatoid Arthritis
547(10)
Ross Penglase
Robert D. Sandler
John Moore
John A. Snowden
59 Hematopoietic Stem Cell Transplantation for Behcet's Syndrome
557(12)
Leandro Lara do Prado
Lilian Piron-Ruiz
Milton Ruiz
Celio Roberto Goncalves
60 Hematopoietic Stem Cell Transplantation and Myasthenia Gravis
569(11)
Osman Radhwi
Harold Atkins
61 Autologous Hematopoietic Stem Cell Transplantation in Stiff Person Spectrum Disorder
580(9)
Zeid Yasiry
Richard K. Burt
Basil Sharrack
62 Hematopoietic Stem Cell Transplant-Based Treatment for Psychiatric Disorders
589(5)
Sophia Chaudry
Sander Markx
63 Hematopoietic Stem Cell Transplantation for Psoriasis and Pemphigus Vulgaris
594(5)
Floyd Silva
John Durkin
Leslie Andritsos
SECTION IX ETHICS AND ECONOMICS
64 Health Economics of Autoimmune Diseases Using Multiple Sclerosis as a Model
599(5)
Daniel M. Hartung
65 Is Health Care a Human Right?
604(4)
Lawrence J. Metzger
66 Ethics of Stem Cells and Stem Cell Transplantation for Autoimmune Diseases
608(4)
Kevin FitzGerald
Appendices: Autoimmune Diseases Indices and Instruments 612(39)
Index 651
Richard K. Burt, MD (www.astemcelljourney.com) is Fulbright Scholar and Professor of Medicine at Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA, and the first Autoimmune Committee Chairperson for the International Bone Marrow Transplant Registry (IBMTR).

Dominique Farge, MD, PhD is Professor of Internal Medicine at Saint-Louis Hospital, Assistance Publique-Hōpitaux de Paris, (AP-HP), University of Paris, Paris, France; Adjunct Professor at McGill University, Montreal, Canada; and Chairperson of the European Society for Blood and Marrow Transplantation Autoimmune Disease Working Party from 2010 to 2016.

Milton A. Ruiz, MD, PhD is former Professor at the University of Sćo Paulo and the head coordinator of the Hematopoietic Stem Cell Transplant Service of the Beneficźncia Portuguesa Hospital of Sćo José do Rio Preto, Sćo Paulo, Brazil.

Riccardo Saccardi, MD is Director of Cellular Therapies and Transfusion Medicine Department at Careggi University Hospital in Florence, Italy and Chairperson of the European Society for Blood and Marrow Transplantation Autoimmune Disease Working Party from 2004 to 2010.

John A. Snowden, MD is Consultant Haematologist & Director of Blood and Marrow Transplantation, Department of Haematology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK; Honorary Professor, Department of Oncology & Metabolism, The University of Sheffield, Sheffield, UK; Honorary Clinical Professor, The Cancer Institute, Department of Haematology, University College London, UK; and Chairperson of the European Society for Blood and Marrow Transplantation Autoimmune Disease Working Party from 2016 to 2020.