Atjaunināt sīkdatņu piekrišanu

Hepatitis C: Antiviral Drug Discovery and Development [Hardback]

Edited by , Edited by
  • Formāts: Hardback, 400 pages, colour plates
  • Izdošanas datums: 01-Mar-2011
  • Izdevniecība: Caister Academic Press
  • ISBN-10: 1904455786
  • ISBN-13: 9781904455783
Citas grāmatas par šo tēmu:
  • Hardback
  • Cena: 287,50 €
  • Grāmatu piegādes laiks ir 3-4 nedēļas, ja grāmata ir uz vietas izdevniecības noliktavā. Ja izdevējam nepieciešams publicēt jaunu tirāžu, grāmatas piegāde var aizkavēties.
  • Daudzums:
  • Ielikt grozā
  • Piegādes laiks - 4-6 nedēļas
  • Pievienot vēlmju sarakstam
  • Formāts: Hardback, 400 pages, colour plates
  • Izdošanas datums: 01-Mar-2011
  • Izdevniecība: Caister Academic Press
  • ISBN-10: 1904455786
  • ISBN-13: 9781904455783
Citas grāmatas par šo tēmu:
This collection of nineteen articles on Hepatitis C showcases state-of-the-art research and highlights new avenues for understanding and treating this dangerous liver disease. Beginning with an overview of the life cycle of the Hepatitis C virus (HCV), topics discussed include animal models for HCV research, accessing public resources for HCV research, drug clinical trial design, protease covalent and non-covalent inhibitors, NS5A inhibitors and examining innate immunity for HCV antiviral therapies. Intended for research scientist, papers include sample data and illustrations as well as voluminous reference material. Contributors include academics and researchers from a variety of universities, laboratories and pharmaceutical companies in the United States, Europe, Australia and Japan. Distributed in the US by ISBS. Annotation ©2011 Book News, Inc., Portland, OR (booknews.com)
List of Contributors
v
Preface ix
1 An Overview of the Hepatitis C Virus Life Cycle
1(48)
Timothy L. Tellinghuisen
2 Hepatitis C Virus-related Assays
49(18)
Zhuhui Huang
Zhaohui Cai
Michael G. Murray
3 Hepatitis C Virus: Public Resources
67(8)
Deborah R. Taylor
4 HCV Databases
75(14)
Carla Kuiken
Richard Scheuermann
5 HCV Infection Systems
89(14)
Takaji Wakita
6 The Chimpanzee Model of Hepatitis C Infections and Small Animal Surrogates
103(34)
Robert E. Lanford
Stanley M. Lemon
Christopher Walker
7 Hepatitis C Virus Drug Pipeline Overview and Clinical Trial Design
137(10)
Jean-Michel Pawlotsky
8 Clinical Virology Support for HCV Drug Development
147(22)
Yupeng He
Liangjun Lu
Akhteruzzaman Molla
9 NS3 Protease Covalent Inhibitors
169(24)
Kevin X. Chen
F. George Njoroge
10 NS3 Protease Non-covalent Inhibitors
193(22)
Brad O. Buckman
Karl Kossen
John B. Nicholas
Scott D. Seiwert
11 Discovery of Hepatitis C Virus NS3-NS4A Complex Inhibitors
215(22)
Mingjun Huang
Kathe Stauber
Atul Agarwal
Milind Deshpande
Avinash Phadke
12 Hepatitis C Virus NS3 Helicase Inhibitors
237(20)
Craig A. Belon
David N. Frick
13 NS4B Targets and Inhibitors
257(14)
Menashe Elazar
Jeffrey S. Glenn
14 NS5A Inhibitors
271(22)
Pilar Najarro
Neil Mathews
Stuart Cockerill
15 Nucleoside Inhibitors of Hepatitis C Virus
293(18)
Klaus Klumpp
Mark Smith
16 NS5B Polymerase Non-nucleoside Inhibitors
311(10)
Martijn Fenaux
Hongmei Mo
17 Hepatitis C Virus Glycoprotein-dependent Entry
321(24)
Heidi E. Drummer
Jane A. McKeating
18 A Perspective on Host Cell Targets and Inhibitors
345(26)
Kai Lin
19 Targeting Innate Immunity for HCV Antiviral Therapy
371(16)
Michael Gale, Jr.
Index 387