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E-grāmata: Human Genome: A User's Guide

4.23/5 (15 ratings by Goodreads)
(American Cancer Society Research Professor and Investigator at the Stowers Institute for Medical Research), (Professor of Ophthalmology and Visual Sciences and Professor of Epidemiology at the University of Michigan in Ann Arbor)
  • Formāts: PDF+DRM
  • Izdošanas datums: 03-Nov-2004
  • Izdevniecība: Academic Press Inc
  • Valoda: eng
  • ISBN-13: 9780080474588
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Human Genome: A User's GuidePalielināt
  • Formāts: PDF+DRM
  • Izdošanas datums: 03-Nov-2004
  • Izdevniecība: Academic Press Inc
  • Valoda: eng
  • ISBN-13: 9780080474588
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This second edition of a very successful text reflects the tremendous pace of human genetics research and the demands that it places on society to understand and absorb its basic implications. The human genome has now been officially mapped and the cloning of animals is becoming a commonplace scientific discussion on the evening news. Join authors Julia Richards and Scott Hawley as they examine the biological foundations of humanity, looking at the science behind the sensation and the current and potential impact of the study of the genome on our society.

The Human Genome, Second Edition is ideal for students and non-professionals, but will also serve as a fitting guide for the novice geneticist by providing a scientific, humanistic, and ethical frame of reference for a more detailed study of genetics.

New in this edition:
· 60% new material, including data from the Human Genome Project and the latest genetics and ethics discussions
· Several new case studies and personal stories that bring the concepts of genetics and heredity to life
· Simplified treatment of material for non-biology majors
· New full-color art throughout the text
· New co-author, Julia Richards, joins R. Scott Hawley in this revision

This rapid revision of a very successful text reflects the tremendous pace of both human genetics research and the increasingly obvious demands that it places on society to understand and absorb its basic implications. The human genome has now been officially mapped and the cloning of animals is becoming a commonplace scientific discussion on the evening news. Join authors Scott Hawley, and Julia Richards on a tour of the fundamentals of the biological foundations of humanity and examine both the science behind the sensation and the current and potential impact of the study of the genome on our society. The Human Genome, Second Edition is also a fitting guide for the novice geneticist by providing a scientific, humanistic, and ethical frame of reference for more detailed study of genetics.

* Revision includes approximately 60% new material, reflecting new scientific data from the Human Genome Project and the latest genetics and ethics discussions
* Some sections have been simplified for non-biology majors and others studying genetics, medicine, and their impact on society
* Includes new colour art
* Looks at sexual development and how genes influence both expression and behaviour

Recenzijas

"This second edition of a very successful text reflects the tremendous pace of human genetics research and the demands that it places on society to understand and absord its basic implications."-BIOWORLD, 2006"The clarity of writing and thought in The Human Genome, A User's Guide makes an understanding of genetics and its impact in modern society accessible to everyone."-Bruce Chase, University of Nebraska at Omaha"It is easy to read, well thought-out, and full of good examples that clearly explain some of the more difficult concepts in modern genetics." -Richard K. Wilson, Washington University"The authors have done a superb job of identifying the key concepts and breaking them down into understandable and relevant explanations..."-Neil Lamb, Emory University"This is an excellent version of classical human genetics for sophomore level science students or for all levels of non-science majors."-John Merriam, University of California at Los Angeles"It is enjoyable to read, clear, and accurate... The first edition was excellent but this one is even better." -Philip Meneely, Haverford College

Papildus informācija

Contains 60% new material, reflecting rapid advances in human gene research and the implications on society!
Acknowledgments ix
Preface xi
SECTION 1 The Basics of Heredity
1(44)
Slaying Molecular Dragons: Brenda's Tale
3(4)
The Answer In A Nutshell: Genes, Proteins, and the Basis of Life
7(8)
Mendel and the Concept of the Gene
15(10)
Human Mendelian Genetics
25(12)
One Man's Trait Is Another Man's Disease
37(8)
SECTION 2 The Central Dogma of Molecular Biology
45(40)
DNA: The Genetic Alphabet
47(8)
The Central Dogma of Molecular Biology: How Genes Encode Proteins
55(10)
Splicing the Modular Gene
65(6)
Orchestrating the Human Genome
71(14)
SECTION 3 How Chromosomes Move
85(40)
So What are Chromosomes Anyway?
87(8)
How Cells Move Your Genes Around
95(12)
Passing Genes Between Generations
107(10)
The Chromosomal Basis of Heredity
117(8)
SECTION 4 Mutation
125(78)
Absent Essentials and Monkey Wrenches
127(12)
How We Detect Mutations
139(14)
We Are All Mutants
153(16)
What Constitutes Normal?
169(8)
Mutations in Mammoth Genes
177(10)
Expanded Repeat Traits
187(16)
SECTION 5 Genes, Chromosomes, and Sex
203(50)
The X and Y Chromosomes: The Odd Couple
205(10)
Genetics of Sex, Gender, and Orientation
215(22)
Aneuploidy: When Too Much or Too Little Counts
237(16)
SECTION 6 Breaking the Rules
253(24)
Imprinting
255(10)
Imitating Heredity: One Trait, Many Causes
265(12)
SECTION 7 The Human Genome Landscape
277(48)
The Human Genome Project
279(8)
There's Cloning and Then There's Cloning
287(12)
The Human Genome Sequence
299(12)
Finding Genes in the Human Genome
311(14)
SECTION 8 Complex and Heterogeneous Traits
325(52)
Genotype Phenotype Correlations
327(10)
How Complex Can It Get?
337(8)
Quantitative Traits
345(8)
The MAOA Gene: Is There a Genetic Basis for Criminality?
353(6)
The Multiple-Hit Hypothesis: The Genetics of Cancer
359(18)
SECTION 9 Genetic Testing and Therapy
377(42)
Genetic Testing and Screening
379(24)
Magic Bullets: The Potential for Gene Therapy
403(16)
SECTION 10 Fears, Faith, and Fantasies
419(22)
Heroes Among Us
421(8)
Fears, Faith, and Fantasies
429(12)
Credits 441(10)
Index 451
Julia E. Richards (PhD, Genetics, University of Wisconsin) is Professor of Ophthalmology and Visual Sciences and Professor of Epidemiology at the University of Michigan in Ann Arbor where she teaches introductory genetics to graduate students in the School of Public Health. She is widely known for her research on inherited eye diseases and has published numerous chapters and research articles focused on human genetics. R. Scott Hawley (PhD, Genetics, University of Washington) is an American Cancer Society Research Professor and Investigator at the Stowers Institute for Medical Research. He has served as President of the Genetics Society of America in 2010 and in 2008 he received that society's Elizabeth W. Jones Award for Excellence in Teaching. He widely known for his teaching, for his research on meiosis and for the authorship of numerous textbooks and research papers.
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