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E-grāmata: Human Hypothalamus: Neuropsychiatric Disorders

Edited by , Edited by (Netherlands Institute for Brain Research, University of Amsterdam, Amsterdam, The Netherlands), Edited by (OLVG Hospitals, Am), Edited by , Edited by (Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Ciudad Universitaria, Mexico D.F.)
  • Formāts: PDF+DRM
  • Sērija : Handbook of Clinical Neurology
  • Izdošanas datums: 07-Jul-2021
  • Izdevniecība: Elsevier Science Publishing Co Inc
  • Valoda: eng
  • ISBN-13: 9780128199749
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  • Formāts: PDF+DRM
  • Sērija : Handbook of Clinical Neurology
  • Izdošanas datums: 07-Jul-2021
  • Izdevniecība: Elsevier Science Publishing Co Inc
  • Valoda: eng
  • ISBN-13: 9780128199749

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The Human Hypothalamus: Neuropsychiatric Disorders, Volume 181 in the Handbook of Clinical Neurology series, provides comprehensive summaries of recent research on the brain and nervous system as they relate to clinical neurology. This volume identifies the neurobiology and neurophysiology of disorders relating to the hypothalamus and provides treatment information for these disorders. Disorders covered include neuropsychiatric, neurodegenerative, periodic, and autoimmune disorders. Coverage includes Alzheimer’s, Parkinson’s, epilepsy, sleep, pain, depression, anxiety, OCD, PTSD, schizophrenia, autism, aggressions, addiction, and more.
  • Summarizes research on how the hypothalamus relates to neurological disorders
  • Contains neuropsychiatric, neurodegenerative, periodic and autonomic disorders
  • Includes the neurobiology of, and treatment for, each disorder
  • Covers depression, anxiety, OCD, PTSD, schizophrenia, autism, aggression, addiction, and more
  • Provides coverage of sleep and pain
Foreword vii
Preface ix
Contributors xiii
1 Introduction: The human hypothalamus and neuropsychiatric disorders
1(8)
D. F. Swaab
R.M. Buijs
F. Kreier
P.J. Lucassen
A. Salehi
SECTION 21 Trauma and iatrogenic disorders
2 Chronic traumatic encephalopathy and the nucleus basalis of Meynert
9(24)
E. J. Mufson
C. Kelley
S.E. Perez
SECTION 22 Neurobehavioral disorders
3 Hypothalamic stress systems in mood disorders
33(16)
F. Holsboer
M. Ising
4 Light therapy for mood disorders
49(14)
B. Bais
W.J.G. Hoogendijk
M.P. Lambregtse-van den Berg
5 Neurobiology of peripartum mental illness
63(20)
J.L. Pawluski
J.E. Swain
J.S. Lonstein
6 The hypothalamo-pituitary-adrenal axis and the autonomic nervous system in burnout
83(12)
A. Sjors Dahlman
I.H. Jonsdottir
C. Hansson
7 Posterior hypothalamus as a target in the treatment of aggression: From lesioning to deep brain stimulation
95(12)
M. Rizzi
O. Gambini
C.E. Marras
8 The implications of hypothalamic abnormalities for schizophrenia
107(14)
H.-G. Bernstein
G. Keilhoff
J. Steiner
9 The promiscuity of the oxytocin-vasopressin systems and their involvement in autism spectrum disorder
121(22)
A.M. Borie
C. Theofanopoulou
E. Andari
SECTION 23 Epilepsy
10 Gelastic seizures and the hypothalamic hamartoma syndrome: Epileptogenesis beyond the lesion?
143(12)
J. Scholly
F. Bartolomei
11 The interactions between reproductive hormones and epilepsy
155(22)
E. Tauboll
J.I.T. Isojarvi
A.G. Herzog
SECTION 24 Neurodegenerative disorders
12 Alternative splicing in aging and Alzheimer's disease: Highlighting the role of tau and estrogen receptor a isoforms in the hypothalamus
177(14)
T.A. Ishunina
13 Cholinergic neurodegeneration in Alzheimer disease mouse models
191(20)
A. Shekari
M. Fahnestock
14 Autonomic disorders in Parkinson disease: Disrupted hypothalamic connectivity as revealed from resting-state functional magnetic resonance imaging
211(12)
E. Dayan
M. Sklerov
15 Hypothalamic a-synuclein and its relation to autonomic symptoms and neuroendocrine abnormalities in Parkinson disease
223(12)
E. De Pablo-Fernandez
T. T. Warner
16 Lewy bodies in the olfactory system and the hypothalamus
235(10)
M.G. Cersosimo
E.E. Benarroch
G.B. Raina
17 Hypothalamic pathology in Huntington disease
245(12)
D.J. van Wamelen
N.A. Aziz
18 Endocrine dysfunction in adrenoleukodystrophy
257(12)
M. Engelen
S. Kemp
F. Eichler
19 Hypothalamic symptoms of frontotemporal dementia disorders
269(14)
R.M. Ahmed
G. Halliday
J.R. Hodges
SECTION 25 Olfactory system
20 The vomeronasal organ: History, development, morphology, and functional neuroanatomy
283(10)
G.S. Stoyanov
N.R. Sapundzhiev
A.B. Tonchev
21 Pheromone effects on the human hypothalamus in relation to sexual orientation and gender
293(14)
Y. Ye
Z. Lu
W. Zhou
22 Kallmann syndrome and idiopathic hypogonadotropic hypogonadism: The role of semaphorin signaling on GnRH neurons
307(10)
A. Cariboni
R. Balasubramanian
23 Olfaction as an early marker of Parkinson's disease and Alzheimer's disease
317(16)
I.M. Walker
M.E. Fullard
J.F. Morley
J.E. Duda
SECTION 26 Autonomic and sleep disorders
24 The hypothalamus and its role in hypertension
333(22)
V.D. Goncharuk
25 The heart is lost without the hypothalamus
355(14)
S. Pyner
26 Sleep disorders and the hypothalamus
369(20)
S. Overeem
R.R.L. van Litsenburg
P.J. Reading
SECTION 27 Addiction and pain
27 Molecular genetics of neurotransmitters and neuropeptides involved in Internet use disorders including first insights on a potential role of hypothalamus' oxytocin hormone
389(12)
C. Sindermann
R. Sariyska
J.D. Elhai
C. Montag
28 The neurobiology of cluster headache
401(16)
M. Leone
S. Ferraro
A.P. Cecchini
SECTION 28 Critical care and brain-death
29 Endocrine interventions in the intensive care unit
417(16)
A. Teblick
L. Langouche
G. Van den Berghe
30 Hypothalamic function in patients diagnosed as brain dead and its practical consequences
433(14)
M. Nair-Collins
A.R. Joffe
Index 447
Dick Swaab (1944) earned his medical and doctoral degrees at the University of Amsterdam, where he became involved in brain research during his third year of medical school. He was Director of the Netherlands Institute for Brain Research from 1978 to 2005. Since 1979 he is Professor of Neurobiology at the Medical Faculty, University of Amsterdam.

In 1985, Dr. Swaab founded the Netherlands Brain Bank (NBB) to serve as a source of clinically and neuropathologically well-documented research tissue. Since its founding, the Brain Bank has provided samples from more than 4,000 autopsies to 500 research groups in 25 countries. He was director of the NBB until 2005.

He is Leader Research team Neuropsychiatric Disorders, Neth. Inst for Neuroscience, an institute of the Royal Netherlands Academy of Arts and Sciences (KNAW). Swaab is also appointed for 2011-2017 Chao Kuang Piu Chair of Zhejiang University, Hangzhou, P.R. China.

His major research interests focus on, sexual differentiation of the human brain in relation to gender identity and sexual orientation, aging of the brain, Alzheimers disease, the neurobiological basis of depression, suicide and eating disorders. He has published over 540 papers in SCI journals, authored more than 200 chapters in books, and edited more than 60 books. Swaab mentored 84 PhD students from which 16 are now full professor. He is Companion in the Order of the Dutch Lion”, bestowed by her Royal Majesty Queen Beatrix of the Netherlands. In 2008 Swaab obtained the Academy medal for his role in national and international neuroscience.

Dick Swaab is author of the 2 volume monograph The Human Hypothalamus that appeared in the Handbook of Clinical Neurology series, Elsevier, Amsterdam (1000 pp) and the Dutch best seller We are our Brains (450.000 copies sold), that is translated in 14 languages. A children's version of the book (You are your brains) has also appeared in Dutch in 2013 and Russian (2014). Swaab's H-factor is 76.

Dr. Ruud M. Buijs is head of the Physiology department of the I.I.Biomedicas at the UNAM university and leader of the group Hypothalamic Integration Mechanisms. In that group, the scientists study how the brain and body interact with each other, and hereby the attention is focussed on autonomic and hormonal regulation of body functions under the influence of the biological clock of the brain. Felix Kreier is a pediatrician and affiliated with OLVG Hospitals in Amsterdam, The Netherlands. Paul J. Lucassen did his PhD in 1995 on Alzheimers Disease at the Netherlands Institute for Brain Research in Amsterdam. After a.o. a postdoc in Leiden, he became Full Professor of Brain Plasticity in 2011 at the Swammerdam Institute for Life Sciences (SILS) of the University of Amsterdam, The Netherlands. His group studies molecular, nutritional, pharmacological and environmental regulation of brain plasticity. They combine molecular tools, in vitro/vivo model systems, human brain tissue, cohort studies and brain imaging. A major focus is on adult neurogenesis and cognition in relation to; (early life) stress, exercise, enrichment, depression, brain insults and dementia. Ahmad Salehi is affiliated with Stanford Medical School, Department of Psychiatry & Behavioral Sciences, in Palo Alto, CA, United States.