Human Organs-on-a-Chip Technology focuses on technology advancement from organ-on-a-chip, multi organs-on-a-chip, and the newest stage of human organs-on-a-chip." Chapters investigate the design, simulation studies, device development, and application of microfluidic systems. In addition, they offer expert perspectives on the development of an alternative test system in the biological evaluation of drugs, cosmetics, chemicals, medical devices, and many others. Lastly, the book addresses issues related to the development of microfluidic devices and alternative test systems in biological and biomedical research.
1. Basics of Microfluidics technology
2. The Physics and Engineering of Flow in Organ on a Chip Devices
3. Importance of Soft lithography
4. Development of microfluidic devices
5. Microfluidics based point of care devices
6. Microfluidics, Organs-on-a-chip and 3D printing
7.Microfluidic platforms: applications and challenges
8. Design and simulation study of Organ-on-a-chip
9. Primary Cell culture for Organ-on-a-chip
10. Vascularisation in organs-on-a-chip
11. Organ-on-a-chip in nanotechnology
12. Organs-on-a-chip in precision medicine
13. Foeto-placental organ-on-a-chip
14. Organs-on-a-chip in drug development
15. Organ-on-a-chip for multianalyte monitoring
16. Organ-on-a-chip for Blood-brain-barrier studies
17. Organs on a chip models for sensor
18. Innovative organs-on-a-chip technology for marine drug development
19. Exposure-on-a-chip as a model for inhalation toxicology and pharmacology
research
20. Brain-on-chip
21. Recent breakthrough in organ-on-a-chip
22. 3D printed microfluidic chips
23. 3D tissue and Organ-on-a-chip models
24. Vascularisation of organoids in microfluidic chips
25. Multiorgans-on-a-chip: Design and applications
26. Multiorgans-on-a-chip for subacute toxicity
27. Multiorgans-on-a-chip for acute toxicity
28. Human organs-on-a-chip for biological evaluation
29. Human organs-on-a-chip for cancer modelling
Dr. Mohanan FNASc, is the Head of the Division of Toxicology, Sree Chitra Tirunal Institute for Medical Sciences and Technology (Govt. of India). He is a visiting professor and visiting researcher at Toyo University, Japan and a Certified Biological Safety Specialist. Previously, he was a JSPS Post doctoral Fellow at the University of Tsukuba, Japan in the field of Neurotoxicity. He joined Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Govt. of India in 1989 and has spent 33 years of professional life working there. As a toxicologist he has been intimately associated with all the medical devices/technologies developed at SCTIMST. He received the lifetime achievement award from the Society of Toxicology India, for the outstanding contribution in the field of toxicology. He also patented an ELISA kit for the measurement of pyrogenicity. Mohanan made significant contributions for the development of medical device regulations in India. He has authored 231 publications and edited 6 books. Presently he is the secretary general of the Society of Toxicology, India.
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