| Contributors |
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xi | |
| Preface |
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xxv | |
| Abbreviations |
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xxvii | |
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SECTION 1 Cardiovascular Disease: Past, Present, and Future |
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1 A History of the Cardiac Diseases, and the Development of Cardiovascular Medicine as a Specialty |
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3 | (16) |
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2 The Global Burden of Cardiovascular Diseases |
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19 | (33) |
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3 Assessing and Improving the Quality of Care in Cardiovascular Medicine |
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52 | (15) |
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SECTION 2 Foundations of Cardiovascular Medicine |
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4 Functional Anatomy of the Heart |
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67 | (34) |
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5 Normal Physiology of the Cardiovascular System |
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101 | (24) |
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Rodrigo Fernandez-Jimenez |
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6 Molecular and Cellular Biology of the Heart |
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125 | (19) |
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7 Biology of the Vessel Wall |
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144 | (17) |
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8 Molecular and Cellular Development of the Heart |
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161 | (13) |
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9 Genetic Basis of Cardiovascular Disease |
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174 | (31) |
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10 Stem Cells and the Cardiovascular System |
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205 | (20) |
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SECTION 3 Evaluation of the Patient |
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11 The History, Physical Examination, and Cardiac Auscultation |
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225 | (27) |
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12 Surface Electrocardiography |
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252 | (66) |
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13 Electrocardiographic Exercise Testing |
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318 | (17) |
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335 | (18) |
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353 | (80) |
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16 Magnetic Resonance Imaging of the Heart |
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433 | (36) |
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17 Computed Tomography of the Heart |
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469 | (30) |
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499 | (54) |
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19 Positron Emission Tomography in Heart Disease |
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553 | (53) |
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20 Cardiac Catheterization, Cardiac Angiography, and Coronary Blood Flow and Pressure Measurements |
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606 | (51) |
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21 Coronary Intravascular Imaging |
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657 | (29) |
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22 Magnetic Resonance Imaging and Computed Tomography of the Vascular System |
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686 | (17) |
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SECTION 4 Systemic Arterial Hypertension |
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23 Epidemiology of Hypertension |
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703 | (17) |
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24 Pathophysiology of Hypertension |
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720 | (31) |
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25 Diagnosis and Treatment of Hypertension |
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751 | (16) |
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SECTION 5 Metabolic Disorders and Cardiovascular Disease |
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26 The Metabolic Syndrome |
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767 | (9) |
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27 Obesity and Cardiovascular Disease |
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776 | (13) |
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28 Diabetes and Cardiovascular Disease |
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789 | (28) |
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817 | (32) |
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SECTION 6 Cigarette Smoking and Cardiovascular Diseases |
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30 Epidemiology of Smoking and Pathophysiology of Cardiovascular Damage |
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849 | (11) |
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31 Preventing and Mitigating Smoking-Related Heart Disease |
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860 | (11) |
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SECTION 7 Atherosclerosis and Coronary Heart Disease |
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32 Atherothrombosis: Disease Burden, Activity, and Vulnerability |
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871 | (9) |
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33 Coronary Thrombosis: Local and Systemic Factors |
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880 | (13) |
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34 Coronary Blood Flow and Myocardial Ischemia |
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893 | (30) |
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35 Nonobstructive Atherosclerotic and Nonatherosclerotic Coronary Heart Disease |
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923 | (23) |
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36 Definitions of Acute Coronary Syndromes |
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946 | (8) |
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37 Pathology of Myocardial Infarction and Sudden Death |
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954 | (23) |
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Rodrigo Fernandez-Jimenez |
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38 Molecular and Cellular Mechanisms of Myocardial Ischemia/Reperfusion Injury |
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977 | (18) |
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39 Evaluation and Management of Non--ST-Segment Elevation Myocardial Infarction |
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995 | (22) |
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40 ST-Segment Elevation Myocardial Infarction |
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1017 | (38) |
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41 Antiplatelet and Anticoagulant Therapy in Acute Coronary Syndromes |
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1055 | (54) |
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42 Percutaneous Coronary Interventions in Acute Myocardial Infarction and Acute Coronary Syndromes |
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1109 | (23) |
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43 The Evaluation and Management of Stable Ischemic Heart Disease |
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1132 | (28) |
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44 Coronary Artery Bypass Grafting and Percutaneous Interventions in Stable Ischemic Heart Disease |
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1160 | (13) |
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45 Rehabilitation of the Patient with Coronary Heart Disease |
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1173 | (14) |
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SECTION 8 Valvular Heart Disease |
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1187 | (9) |
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1196 | (19) |
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48 Degenerative Mitral Valve Disease |
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1215 | (23) |
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49 Ischemic Mitral Regurgitation |
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1238 | (10) |
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1248 | (12) |
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51 Tricuspid and Pulmonary Valve Disease |
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1260 | (17) |
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52 Prosthetic Heart Valves |
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1277 | (23) |
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53 Antithrombotic Therapy for Valvular Heart Disease |
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1300 | (10) |
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54 Management of Mixed Valvular Heart Disease |
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1310 | (9) |
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SECTION 9 Congenital Heart Disease |
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55 Mendelian Basis of Congenital and Other Cardiovascular Diseases |
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1319 | (44) |
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56 Congenital Heart Disease in Adolescents and Adults |
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1363 | (34) |
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SECTION 10 Myocardial, Pericardial, and Endocardial Diseases |
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57 Classification of Cardiomyopathies |
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1397 | (11) |
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58 Dilated Cardiomyopathy |
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1408 | (35) |
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59 Hypertrophic Cardiomyopathies |
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1443 | (22) |
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60 Left Ventricular Noncompaction |
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1465 | (17) |
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61 Restrictive Heart Diseases |
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1482 | (27) |
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62 Arrhythmogenic Cardiomyopathy |
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1509 | (19) |
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1528 | (33) |
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64 The Athlete and the Cardiovascular System |
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1561 | (10) |
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65 Cardiovascular Disease in the Elderly: Pathophysiology and Clinical Implications |
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1571 | (23) |
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1594 | (27) |
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67 Infective Endocarditis |
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1621 | (30) |
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68 Pathophysiology of Heart Failure |
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1651 | (23) |
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69 The Epidemiology of Heart Failure |
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1674 | (16) |
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70 The Diagnosis and Management of Chronic Heart Failure |
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1690 | (36) |
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71 Evaluation and Management of Acute Heart Failure |
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1726 | (20) |
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Michelle Weisfelner Bloom |
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72 Cardiac Transplantation |
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1746 | (22) |
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73 Mechanically Assisted Circulation |
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1768 | (17) |
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SECTION 12 Cardiopulmonary Disease |
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74 Pulmonary Hypertension |
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1785 | (24) |
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1809 | (26) |
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Rodrigo Fernandez-Jimenez |
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76 Cor Pulmonale: The Heart in Parenchymal Lung Disease |
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1835 | (6) |
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77 Sleep-Disordered Breathing and Cardiac Disease |
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1841 | (24) |
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SECTION 13 Rhythm and Conduction Disorders |
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78 Electrophysiologic Anatomy |
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1865 | (16) |
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79 Mechanisms of Cardiac Arrhythmias and Conduction Disturbances |
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1881 | (29) |
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80 Genetics of Channelopathies and Clinical Implications |
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1910 | (13) |
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81 Approach to the Patient with Cardiac Arrhythmias |
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1923 | (15) |
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82 Invasive Diagnostic Electrophysiology |
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1938 | (12) |
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83 Atrial Fibrillation, Atrial Flutter, and Atrial Tachycardia |
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1950 | (17) |
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84 Supraventricular Tachycardia: Atrial Tachycardia, Atrioventricular Nodal Reentry, and Wolff-Parkinson-White Syndrome |
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1967 | (16) |
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85 Ventricular Arrhythmias |
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1983 | (23) |
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2006 | (23) |
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2029 | (18) |
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88 Catheter-Ablative Techniques |
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2047 | (19) |
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89 Pacemakers and Defibrillators |
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2066 | (32) |
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90 Diagnosis and Management of Syncope |
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2098 | (15) |
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2113 | (31) |
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92 Cardiopulmonary and Cardiocerebral Resuscitation |
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2144 | (13) |
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SECTION 14 Diseases of the Great Vessels and Peripheral Vessels |
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2157 | (38) |
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94 Cerebrovascular Disease and Neurologic Manifestations of Heart Disease |
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2195 | (27) |
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95 Carotid Artery Stenting |
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2222 | (26) |
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96 Diagnosis and Management of Diseases of the Peripheral Arteries |
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2248 | (13) |
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97 Diagnosis and Management of Diseases of the Peripheral Venous System |
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2261 | (14) |
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SECTION 15 Miscellaneous Conditions and Cardiovascular Disease |
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98 Perioperative Evaluation for Noncardiac Surgery |
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2275 | (9) |
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99 Anesthesia and the Patient with Cardiovascular Disease |
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2284 | (9) |
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Alexander J. C. Mittnacht |
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100 Rheumatologic Diseases and the Cardiovascular System |
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2293 | (15) |
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101 The Diagnosis and Management of Cardiovascular Diseases in Patients with Cancer |
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2308 | (20) |
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102 HIV/AIDS and the Cardiovascular System |
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2328 | (17) |
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103 Heart Disease in Pregnancy |
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2345 | (19) |
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104 Traumatic Heart Disease |
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2364 | (5) |
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105 The Kidney in Heart Disease |
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2369 | (19) |
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106 Exercise in Health and Cardiovascular Disease |
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2388 | (13) |
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SECTION 16 Populations and Social Determinants of Cardiovascular Disease |
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107 Social Determinants of Cardiovascular Disease |
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2401 | (13) |
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108 Women and Ischemic Heart Disease: An Evolving Saga |
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2414 | (20) |
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109 Race, Ethnicity, and Cardiovascular Disease |
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2434 | (15) |
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110 Environment and Heart Disease |
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2449 | (10) |
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111 Behavioral Cardiology: Epidemiology, Pathophysiology, and Clinical Management |
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2459 | (13) |
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112 Economics and Cost-Effectiveness in Cardiology |
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2472 | |
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| Index |
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178 | |
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