Contributors |
|
xiii | |
Preface to the Third Edition |
|
xvii | |
|
PART 1 METHODS IN INFECTIOUS DISEASE EPIDEMIOLOGY |
|
|
1 | (464) |
|
Chapter 1 Early History of Infectious Disease: Epidemiology and Control of Infectious Diseases |
|
|
3 | (16) |
|
|
|
|
3 | (1) |
|
|
3 | (1) |
|
|
4 | (2) |
|
The Observation and Care of Patients |
|
|
6 | (1) |
|
The Development of Statistics and Surveillance |
|
|
7 | (1) |
|
The Discovery of Microorganisms |
|
|
8 | (4) |
|
|
12 | (1) |
|
|
13 | (2) |
|
The Infectious Diseases Challenge |
|
|
15 | (1) |
|
|
16 | (3) |
|
Chapter 2 Epidemiology of Infectious Disease: General Principles |
|
|
19 | (26) |
|
|
|
19 | (1) |
|
The Classification of Infectious Diseases |
|
|
19 | (6) |
|
Epidemiologic Characteristics of Infectious Diseases |
|
|
25 | (8) |
|
Surveillance of Infectious Diseases |
|
|
33 | (1) |
|
Temporal Trends of Infectious Diseases |
|
|
33 | (7) |
|
Recent Trends in Infectious Disease Morbidity and Mortality in the United States |
|
|
40 | (1) |
|
Recent Worldwide Trends in Infectious Disease Morbidity and Mortality |
|
|
40 | (2) |
|
|
42 | (3) |
|
|
45 | (32) |
|
|
|
|
45 | (1) |
|
|
46 | (2) |
|
Epidemiologic Study Designs |
|
|
48 | (17) |
|
Measurement and Measures of Disease Occurrence |
|
|
65 | (4) |
|
Population Comparisons and Epidemiologic Inference |
|
|
69 | (3) |
|
|
72 | (5) |
|
Chapter 4 Prevention of Infectious Diseases |
|
|
77 | (28) |
|
|
|
|
|
77 | (1) |
|
Individual Prevention Measures |
|
|
77 | (11) |
|
Community Prevention Measures |
|
|
88 | (8) |
|
|
96 | (1) |
|
|
97 | (8) |
|
Chapter 5 Outbreak Epidemiology |
|
|
105 | (26) |
|
|
|
|
|
105 | (1) |
|
Surveillance and Outbreak Detection |
|
|
106 | (1) |
|
|
107 | (20) |
|
|
127 | (1) |
|
|
127 | (4) |
|
Chapter 6 Infectious Disease Dynamics |
|
|
131 | (36) |
|
|
|
|
131 | (1) |
|
|
131 | (2) |
|
Determinants of Epidemic Growth |
|
|
133 | (2) |
|
Elements of the Course of Infection |
|
|
135 | (1) |
|
Dynamic Models of the Epidemic Process |
|
|
136 | (3) |
|
Host Population Structure |
|
|
139 | (2) |
|
|
141 | (4) |
|
Dynamic Populations and Pathogens |
|
|
145 | (4) |
|
Stochasticity and Randomness |
|
|
149 | (1) |
|
|
150 | (2) |
|
Infectious Disease Dynamics and Public Health |
|
|
152 | (6) |
|
|
158 | (1) |
|
|
158 | (9) |
|
Chapter 7 Geographic Information Systems |
|
|
167 | (20) |
|
|
|
170 | (3) |
|
|
173 | (11) |
|
|
184 | (1) |
|
|
185 | (2) |
|
Chapter 8 Microbiology Tools for the Epidemiologist |
|
|
187 | (32) |
|
|
|
Taxonomy, Classification, and Structure of Infectious Agents |
|
|
188 | (1) |
|
|
189 | (2) |
|
|
191 | (7) |
|
|
198 | (6) |
|
|
204 | (6) |
|
|
210 | (8) |
|
|
218 | (1) |
|
Chapter 9 Molecular Epidemiology and Infectious Diseases |
|
|
219 | (34) |
|
|
|
|
|
Application of Typing Techniques |
|
|
219 | (1) |
|
Definitions and Background |
|
|
220 | (3) |
|
Molecular Biology Tools Available to the Molecular Epidemiologist |
|
|
223 | (6) |
|
Specific Techniques of Molecular Epidemiology |
|
|
229 | (14) |
|
|
243 | (2) |
|
|
245 | (1) |
|
|
245 | (8) |
|
Chapter 10 The Immune System and Host Defense Against Infections |
|
|
253 | (20) |
|
|
|
|
|
253 | (2) |
|
|
255 | (4) |
|
After Antigen Binding: Immune Activation |
|
|
259 | (1) |
|
Dealing with the Pathogen: Immune Effector Mechanisms |
|
|
259 | (3) |
|
Cytokines of the Innate and Adaptive Immune Systems |
|
|
262 | (3) |
|
The Role of Cytokine Expression in Defining Functionally Different Effector CD4 T-Cell Lineages |
|
|
265 | (1) |
|
|
265 | (2) |
|
Respiratory Immune Environment |
|
|
267 | (1) |
|
Common Mucosal Immune System |
|
|
267 | (1) |
|
Tolerance and the Regulation of the Immune Response |
|
|
267 | (1) |
|
Selective Immune Deficiencies: Windows into the Normal Roles and Functions of the Immune System |
|
|
267 | (2) |
|
|
269 | (1) |
|
Recommended Textbooks of Immunology |
|
|
269 | (1) |
|
|
270 | (3) |
|
Chapter 11 Vaccines: Past, Present, and Future |
|
|
273 | (32) |
|
|
|
|
273 | (1) |
|
Active Versus Passive Immunization |
|
|
274 | (1) |
|
|
274 | (6) |
|
|
280 | (2) |
|
|
282 | (2) |
|
Vaccine Efficacy and Vaccine Effectiveness |
|
|
284 | (2) |
|
|
286 | (2) |
|
Monitoring Adverse Events and Vaccine Safety |
|
|
288 | (2) |
|
Direct Impact of Vaccination |
|
|
290 | (5) |
|
The Role of Vaccines in Eradication of Specific Diseases |
|
|
295 | (4) |
|
Barriers to Vaccine Implementation and Coverage |
|
|
299 | (1) |
|
|
300 | (5) |
|
Chapter 12 Nutrition and Infection |
|
|
305 | (24) |
|
|
|
|
|
305 | (1) |
|
The Effects of Infection on Nutritional Status |
|
|
305 | (1) |
|
The Effects of Malnutrition on Host Defense Mechanisms |
|
|
306 | (1) |
|
Malnutrition and Specific Infectious Diseases |
|
|
306 | (2) |
|
Micronutrients and Immunity to Infectious Diseases |
|
|
308 | (4) |
|
Assessment of Nutritional Status |
|
|
312 | (6) |
|
|
318 | (1) |
|
|
318 | (11) |
|
Chapter 13 Emerging and New Infectious Diseases |
|
|
329 | (40) |
|
|
Responses to the Threat of Emerging Infections |
|
|
329 | (1) |
|
Factors in the Emergence of Infectious Diseases |
|
|
330 | (16) |
|
Notable Emerging Infectious Diseases |
|
|
346 | (13) |
|
Newly Discovered Pathogens |
|
|
359 | (1) |
|
|
360 | (9) |
|
Chapter 14 Healthcare-Associated Infections |
|
|
369 | (96) |
|
|
|
|
|
369 | (1) |
|
The Magnitude of Problem of HAIs |
|
|
370 | (1) |
|
|
371 | (2) |
|
|
373 | (4) |
|
Pathophysiology and Risk Factors |
|
|
377 | (2) |
|
Etiology and Transmission |
|
|
379 | (1) |
|
|
380 | (7) |
|
Epidemiologically Important Pathogens and Emerging Pathogens |
|
|
387 | (11) |
|
Control and Preventive Strategies |
|
|
398 | (3) |
|
The Need for Integrated Infection Control Programs |
|
|
401 | (2) |
|
|
403 | (1) |
|
|
403 | (62) |
|
PART 2 AIRBORNE TRANSMISSION |
|
|
465 | (146) |
|
Chapter 15 Epidemiology and Prevention of Influenza |
|
|
467 | (18) |
|
|
|
467 | (1) |
|
Clinical Features of Influenza |
|
|
467 | (1) |
|
|
467 | (1) |
|
|
468 | (1) |
|
|
468 | (1) |
|
|
469 | (1) |
|
Epidemiology of Epidemics and Pandemics |
|
|
469 | (3) |
|
Influenza in Tropical and Subtropical Regions |
|
|
472 | (2) |
|
Mechanisms of Antigenic Variation |
|
|
474 | (2) |
|
Epizootic Infections and Evolutionary History |
|
|
476 | (1) |
|
Prevention Strategies and Treatment |
|
|
477 | (3) |
|
|
480 | (1) |
|
|
481 | (1) |
|
|
482 | (3) |
|
|
485 | (24) |
|
|
|
|
485 | (1) |
|
|
485 | (2) |
|
Biologic Characteristics of the Measles Virus |
|
|
487 | (1) |
|
|
488 | (3) |
|
Laboratory Diagnosis of Measles |
|
|
491 | (1) |
|
Epidemiologic Characteristics |
|
|
491 | (1) |
|
|
492 | (1) |
|
Population Size and Measles Virus Transmission |
|
|
492 | (2) |
|
Measles Mortality and Case Fatality |
|
|
494 | (1) |
|
|
495 | (2) |
|
Measles Control, Elimination, and Eradication |
|
|
497 | (6) |
|
|
503 | (1) |
|
|
503 | (1) |
|
|
503 | (6) |
|
Chapter 17 Global Epidemiology of Meningococcal Infections |
|
|
509 | (14) |
|
|
|
|
509 | (1) |
|
|
509 | (1) |
|
|
510 | (1) |
|
|
510 | (1) |
|
|
510 | (1) |
|
|
511 | (1) |
|
|
511 | (2) |
|
|
513 | (1) |
|
|
514 | (2) |
|
|
516 | (1) |
|
|
517 | (4) |
|
|
521 | (2) |
|
|
523 | (38) |
|
|
|
|
|
523 | (1) |
|
|
524 | (3) |
|
|
527 | (1) |
|
|
528 | (1) |
|
|
528 | (4) |
|
|
532 | (1) |
|
Epidemiology: Global Prevalence and Incidence |
|
|
533 | (3) |
|
Natural History of Tuberculosis |
|
|
536 | (1) |
|
Mechanism of Transmission |
|
|
537 | (1) |
|
Risk Factors Associated with Infection |
|
|
538 | (1) |
|
Risk Factors Associated with Development of Disease |
|
|
538 | (7) |
|
|
545 | (2) |
|
Tuberculosis Control Strategies: Case Finding and Treatment |
|
|
547 | (3) |
|
|
550 | (1) |
|
|
551 | (10) |
|
Chapter 19 The Epidemiology of Acute Respiratory Infections |
|
|
561 | (50) |
|
|
|
|
561 | (1) |
|
|
561 | (6) |
|
Classification of Acute Respiratory Infections |
|
|
567 | (2) |
|
Pathogens Responsible for Acute Respiratory Infections |
|
|
569 | (4) |
|
|
573 | (12) |
|
Efficient Methods of Data Collection to Evaluate Respiratory Epidemiology |
|
|
585 | (2) |
|
Prevention of Respiratory Infections |
|
|
587 | (6) |
|
|
593 | (2) |
|
|
595 | (16) |
|
PART 3 ORAL TRANSMISSION OF INFECTION |
|
|
611 | (38) |
|
Chapter 20 Diarrheal Diseases |
|
|
613 | (22) |
|
|
Christa L. Fischer Walker |
|
|
|
|
613 | (1) |
|
General Epidemiology Definitions |
|
|
613 | (1) |
|
|
614 | (1) |
|
|
614 | (2) |
|
|
616 | (1) |
|
|
617 | (6) |
|
|
623 | (2) |
|
|
625 | (1) |
|
|
626 | (1) |
|
|
626 | (1) |
|
|
627 | (8) |
|
Chapter 21 Transmissible Spongiform Encephalopathies |
|
|
635 | (14) |
|
|
|
635 | (1) |
|
|
635 | (1) |
|
|
636 | (1) |
|
Creutzfeldt-Jakob Disease |
|
|
637 | (8) |
|
Chronic Wasting Disease of Mule Deer and Elk |
|
|
645 | (1) |
|
|
646 | (3) |
|
PART 4 BLOOD AND BODY FLUID AS A RESERVOIR OF INFECTIOUS DISEASES |
|
|
649 | (174) |
|
Chapter 22 Human Immunodeficiency Virus Infections and the Acquired Immunodeficiency Syndrome |
|
|
651 | (72) |
|
|
|
|
651 | (1) |
|
|
652 | (1) |
|
|
652 | (2) |
|
|
654 | (3) |
|
AIDS-Related Opportunistic Infections |
|
|
657 | (2) |
|
Host Factors in Susceptibility or Resistance to HIV Infection and Disease Progression |
|
|
659 | (3) |
|
Inflammation and Microbial Translocation |
|
|
662 | (1) |
|
|
662 | (1) |
|
Impact of Coinfections on HIV |
|
|
663 | (3) |
|
|
666 | (7) |
|
Modes of Transmission and Risk Factors |
|
|
673 | (9) |
|
|
682 | (6) |
|
|
688 | (2) |
|
Social and Cultural Factors |
|
|
690 | (1) |
|
|
690 | (9) |
|
Addressing the AIDS Pandemic |
|
|
699 | (2) |
|
|
701 | (1) |
|
|
702 | (21) |
|
Chapter 23 Viral Hepatitis |
|
|
723 | (58) |
|
|
|
|
723 | (1) |
|
Biologic Basis for Transmission |
|
|
724 | (1) |
|
|
724 | (1) |
|
|
725 | (5) |
|
|
730 | (13) |
|
|
743 | (2) |
|
|
745 | (10) |
|
|
755 | (3) |
|
|
758 | (1) |
|
|
758 | (23) |
|
Chapter 24 Sexually Transmitted Diseases |
|
|
781 | (42) |
|
|
|
781 | (1) |
|
Transmission Modes: The Definition of a Sexually Transmitted Disease |
|
|
781 | (1) |
|
|
782 | (1) |
|
|
783 | (3) |
|
Pelvic Inflammatory Disease |
|
|
786 | (1) |
|
|
787 | (3) |
|
|
790 | (3) |
|
|
793 | (1) |
|
Human Papillomavirus Infection |
|
|
794 | (2) |
|
|
796 | (3) |
|
Control of Sexually Transmitted Diseases as an HIV Prevention Intervention |
|
|
799 | (1) |
|
Epidemiology and Behavior |
|
|
800 | (2) |
|
|
802 | (1) |
|
Prevention Issues Specific to Women |
|
|
803 | (1) |
|
Core Groups and Targeting |
|
|
803 | (2) |
|
|
805 | (1) |
|
Innovative STD Control Methods |
|
|
806 | (1) |
|
|
807 | (1) |
|
|
807 | (1) |
|
|
808 | (15) |
|
PART 5 VECTOR-BORNE AND PARASITE DISEASES |
|
|
823 | |
|
Chapter 25 Emerging Vector-Borne Diseases |
|
|
825 | (36) |
|
|
|
825 | (1) |
|
Arthropod-Borne Virus Infections |
|
|
825 | (1) |
|
|
826 | (1) |
|
Dengue and Other Mosquito-Borne Infections |
|
|
826 | (5) |
|
West Nile Virus in North America |
|
|
831 | (10) |
|
Japanese Encephalitis Virus |
|
|
841 | (2) |
|
|
843 | (2) |
|
|
845 | (1) |
|
Tick-Borne Encephalitis Virus |
|
|
846 | (1) |
|
Other Mosquito-Borne Encephalitis Viruses in North America |
|
|
846 | (6) |
|
Other Tick-Borne Infections |
|
|
852 | (1) |
|
|
853 | (2) |
|
|
855 | (1) |
|
|
855 | (1) |
|
|
855 | (6) |
|
|
861 | (20) |
|
|
|
861 | (1) |
|
Clinical Picture and Biological Information |
|
|
862 | (4) |
|
|
866 | (2) |
|
|
868 | (1) |
|
|
868 | (1) |
|
|
868 | (3) |
|
|
871 | (1) |
|
|
871 | (1) |
|
|
872 | (1) |
|
|
872 | (1) |
|
|
873 | (8) |
|
Chapter 27 The Epidemiology and Control of Malaria |
|
|
881 | (36) |
|
|
|
Background, History, and Public Health Importance |
|
|
881 | (3) |
|
The Biology of Malaria Parasites and Anopheline Vectors |
|
|
884 | (4) |
|
|
888 | (2) |
|
Pathogenesis in Individual Humans |
|
|
890 | (2) |
|
The Diversity of Falciparum Malaria Disease |
|
|
892 | (4) |
|
Human Activities, Climate Change with Global Warming, and the Epidemiology of Malaria |
|
|
896 | (1) |
|
|
897 | (2) |
|
|
899 | (2) |
|
|
901 | (2) |
|
|
903 | (3) |
|
The Future of Malaria Control and Elimination |
|
|
906 | (2) |
|
|
908 | (9) |
|
Chapter 28 Epidemiology of Helminth Infections |
|
|
917 | |
|
|
|
917 | (1) |
|
Hookworm Parasites of Humans |
|
|
917 | (3) |
|
Schistosome Parasites in Humans |
|
|
920 | (5) |
|
|
925 | (3) |
|
Control of Neglected Tropical Diseases |
|
|
928 | (1) |
|
|
928 | (3) |
Index |
|
931 | |