This volume considers the many infectious diseases that have been associated with cognitive and neuropsychiatric function to better understand the role infections play in neurocognitive and neuropsychiatric disorders.
Neurocognitive and neuropsychiatric disorders contribute to a substantial amount of global morbidity and, as such, the identification of their causes is paramount to understanding their underlying pathophysiology as well as treatment and prevention strategies.
Infectious Diseases in Neurocognitive and Neuropsychiatric Medicine considers the many infectious diseases that have been associated with cognitive and neuropsychiatric function. In Parts I-III, each chapter focuses on a different disease to cover a range of viral, bacterial, and parasitic diseases in neurocognitive and neuropsychiatric medicine. Part IV considers infectious diseases and clinical conditions and syndromes, while Part V examines the relationship between neurocognitive and neuropsychiatric function and the microbiome and Part VI the relationship with childhood development.
In addition to molecular and clinical descriptions of the infectious diseases themselves, many chapters also explore the diseases' basic epidemiological features to consider where they may be exerting the greatest impact on cognitive and neuropsychiatric function. Where they exist, the possible mitigating factors and treatments for the neuropsychiatric and cognitive dysfunction that can be associated with these infectious diseases are also explored.
In doing so, this volume examines the neurocognitive and neuropsychiatric disorders associated with infectious disease to better understand the role infections play.
Dawson W. Hedges, Shawn D. Gale, and Lance D. Erickson: Introduction
Part I - Viral Diseases in Neurocognitive and Neuropsychiatric Medicine
1: Paul Bernard Foley: The Psychiatric Phenomena of Encephalitis Lethargica
2: Guy D. Eslick: The Association between Herpes Simplex Virus (HSV) and
Neurocognitive, Neuropsychiatric Disorders and Dementia
3: Tshala-Katumbay D. Desire, Mbusa J. Kombi, and Michael J. Boivin:
Neurobola
4: Stuti Chakraborty: Neurocognitive, Neuropsychiatric, and Neurological
Aspects of Severe Acute Respiratory Syndrome - Coronavirus 2 (SARS-CoV2)
(COVID-19)
5: Guy D. Eslick: The Association Between Human Cytomegalovirus and
Neurocognitive Disorders and Dementia
6: Martins Nweke, Shawn D. Gale, and Dawson W. Hedges: Human Immunodeficiency
Virus
7: Lance D. Erickson and Dawson W. Hedges: Neurocognitive, Neuropsychiatric
and Neurological Aspects of Human T-Cell Lymphotropic Virus - Type 1
Part II - Bacterial Diseases in Neurocognitive and Neuropsychiatric Medicine
8: Arielle P. Davis: Syphilis
9: Pegah Touradji: Post-Treatment Lyme Disease Neuropsychological and
Neuropsychiatric Functioning
10: Peter K. Panegyres: Whipple's Disease: Neurology and Neuropsychiatry
11: May A. Beydoun and Ziad W. El-Haji: Helicobacter pylori and Cognitive
Dysfunction
12: Sofiati Dian and Paulus Anam Ong: Neurocognitive Dysfunction Associated
with Tuberculous Meningitis
Part III - Parasitic Diseases in Neurocognitive and Neuropsychiatric
Medicine
13: Michael J. Boivin and Jonathan K. Stiles: Cerebral Malaria and its
Neuroinflammatory, Cognitive, and Neuropsychiatric Associations
14: Jaroslav Flegr: Toxoplasmosis, Behaviour, and Cognition
15: Leonard Ngarka and Alfred K. Njamnshi: Neurocognitive and
Neuropsychiatric Manifestations of Human African Trypanosomiasis
16: Celia V. Holland: Associations Between Toxocara and Neurocognitive
Function
17: Shawn D. Gale and Dawson W. Hedges: Effects of Neurocysticercosis on
Cognitive and Neuropsychiatric Function
Part IV - Infectious Diseases and Clinical Conditions and Syndromes
18: Rabporn Suntornlohanakul and E. Ann Yeh: Acute Necrotizing Encephalopathy
of Childhood
19: Thomas J. Farrer: Dementia Risk Associated with Infectious Disease
20: Nicky Dunn and Anna Fogdell-Hahn: Multiple Sclerosis
21: Chris H. Miller, Liz Pritchard, Marisol Duran, Martin Shapiro, Matthew D.
Sacchet, and Ellen Woo: Infectious Diseases in Major Depressive Disorder,
Bipolar Disorder, and Obsessive-Compulsive Disorder
22: Kenneth J. Friedman, Ilene S. Ruhoy, Patricia A. Fennell, and Shane
George: The Possible Infectious Origins of Myalgic Encephalomyelitis/Chronic
Fatigue Syndrome and Fibromyalgia and Other Infectious Diseases Causing
Cognitive Consequences
Part V - The Microbiome and Neurocognitive and Neuropsychiatric Function
23: Rebecca A. Lundwall: Associations Between the Microbiome and
Neurocognitive and Neuropsychiatric Function
Part VI - Global Issues of Infectious Disease and Neuropsychological and
Neuropsychiatric Function
24: Shawn D. Gale and Dawson W. Hedges: Effects of Infectious Disease on
Childhood and Brain Development and Their Association with Poverty
Dawson W. Hedges is a Professor of Psychology at Brigham Young University. His research interests include the associations between environmental exposures and infectious diseases with neurocognitive and neuropsychiatric outcomes.
Shawn D. Gale is a Professor of Psychology at Brigham Young University. He was trained as a clinical neuropsychologist and worked in clinical settings for many years. His centre on brain-behaviour relationships including the neurocognitive and neuropsychiatric effects of infectious disease.
Lance D. Erickson is a Professor of Sociology at Brigham Young University. His research focuses on the early- and mid-life social and psychological correlates of cognitive functioning in later-life and how social locations are implicated in the relationship between infection and neurocognitive and neuropsychiatric outcomes.