International Review of Neurobiology, Volume 56 [Hardback]

CONTRIBUTORS		viii
Behavioral Mechanisms and the Neurobiology of Conditioned Sexual Responding
MARK KRAUSE
I. Introduction		1	(3)
II. Pavlovian Conditioning of Sexual Responses		4	(1)
III. Hormones and Sexual Conditioning		5	(4)
IV. Sexual Conditioning and the Brain		9	(6)
V. Behavior Systems and Biological Constraints on Learning		15	(3)
VI. Conditioning and the Sexual Behavior System of Quail: The Role of Species-typical Cues		18	(4)
VII. Pavlovian Conditioning and Reproductive Success		22	(4)
VIII. Conclusions		26	(3)
References		29	(7)
NMDA Receptors in Alcoholism
PAULA L. HOFFMAN
I. Alcohol Dependence		36	(2)
II. The NMDA Receptor		38	(4)
III. Acute Effect of Ethanol on the NMDA Receptor		42	(6)
IV. Role of the NMDA Receptor in the Perception of Ethanol's Effects		48	(3)
V. Role of the NMDA Receptor in Adaptation to Ethanol		51	(12)
VI. The NMDA Receptor and Pharmacotherapy of Alcohol Dependence		63	(1)
VII. Conclusions		64	(1)
References		64	(21)
Processing and Representation of Species-Specific Communication Calls in the Auditory System of Bats
GEORGE D. POLLAK, ACHIM KLUG, AND ERIC E. BAUER
I. Introduction		85	(1)
II. General Features of the Mammalian Auditory System		86	(3)
III. The Structure of Communication Calls Emitted by Mexican Free-tailed Bats		89	(1)
IV. Processing and Representation of Communication Sounds in a Lower Auditory Nucleus		89	(5)
V. The Population of DNLL Neurons Reproduce the Spectral and Temporal Features of any Complex Signal		94	(1)
VI. Processing and Representation of Communication Sounds is More Complex in the Inferior Colliculus		95	(4)
VII. Progressive Transformations Occur along the Auditory Pathway but are Scrambled in the IC		99	(1)
VIII. Due to Selectivity, Each Call is Coded in the Inferior Colliculus by a Unique Population Response		100	(1)
IX. Processing in the Cortex		101	(2)
X. The Biosonar Calls of the Mustache Bat		103	(2)
XI. The Auditory Cortex of the Mustache Bat		105	(2)
XII. The Mustache Bat Auditory Cortex is Well Adapted for Processing Both Biosonar and Communication Calls		107	(1)
XIII. Structure of the Mustache Bats' Social Communication Calls		107	(1)
XIV. Responses of FM-FM Neurons in the Mustache Bat Cortex to Social Communication Calls		108	(2)
XV. Is Combinatorial Sensitivity an Emergent Property in the Forebrain of Vertebrates?		110	(1)
XVI. Mechanisms that Generate Combination Sensitivity		111	(2)
XVII. Implications for Hierarchical Processing		113	(1)
XVIII. Concluding Comments		114	(1)
References		115	(8)
Central Nervous System Control of Micturition
GERT HOLSTEGE AND LEONORA J. MOUTON
I. Introduction		123	(2)
II. Motoneurons Innervating Bladder and Urethral Sphincter		125	(3)
III. Sacral Cord Micturition Reflexes		128	(1)
IV. Brainstem-Spinal Cord Pathways Coordinate Bladder and Sphincter Motoneurons		129	(5)
V. Afferent Systems of the M-region		134	(7)
VI. Conclusions		141	(1)
References		141	(7)
The Structure and Physiology of the Rat Auditory System: An Overview
MANUEL MALMIERCA
I. Introduction		148	(1)
II. The Cochlear Nuclear Complex		149	(7)
III. The Superior Olivary Complex		156	(6)
IV. The Nuclei of the Lateral Lemniscus		162	(5)
V. The Inferior Colliculus		167	(8)
VI. The Medial Geniculate Body		175	(6)
VII. The Auditory Cortex		181	(5)
VIII. The Descending Auditory Pathway		186	(4)
IX. Concluding Remarks		190	(1)
X. Acknowledgments		190	(1)
References		191	(22)
Neurobiology of Cat and Human Sexual Behavior
G. HOLSTEGE AND JR. GEORGIANS
I. The Circuit for the Mating Reflex in Cat		213	(4)
II. Central Control of Mating Behavior in Humans		217	(4)
III. Differences in Central Nervous system Control of Sexual Behavior Between Rodents and Primates		221	(2)
References		223	(4)
INDEX		227	(6)
CONTENTS OF RECENT VOLUME		233

Professor Peter Jenner is a specialist in preclinical aspects of neurodegenerative diseases, notably Parkinsons disease. He has spent the major part of his career at Kings College London where he was Head of Pharmacology for 14 years before returning to his research roots and subsequently becoming Emeritus Professor of Pharmacology. Peter has expertise in drug metabolism and pharmacokinetics but neuropharmacology based on functional models of neurodegenerative diseases has formed the major focus of his work. Peter holds a BPharm, PhD and DSc degree from the University of London. He has published well over 1000 articles with more than 700 peer reviewed papers. He is a Fellow of the Royal Pharmaceutical Society, the British Pharmacological Society, the Royal Society of Medicine and of Kings College London. Peter was recently honoured with a Doctor Honoris Causa degree from Carol Davila University of Medicine and Pharmacy, Bucharest and made an Honorary Fellow of The British Pharmacological Society for his contribution to research in to movement disorders.

Peter has worked closely with the pharmaceutical industry for many years and acts as an adviser and consultant to both major pharma and biotech companies. He has a wide knowledge of the drug discovery and drug development process and has been involved from molecule synthesis through to drug registration for use in man. Peter was the Founder, Director and Chief Scientific Officer of Proximagen, a biotech focussed on the treatment and cure of neurodegenerative diseases that was listed on AIMs and subsequently purchased by a US based healthcare company. He is a regular speaker at international meetings and also takes time to speak at Parkinsons disease patient-carer groups across the UK.