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E-grāmata: Linearly Polarized IR Spectroscopy: Theory and Applications for Structural Analysis

(Plovdiv University, Bulgaria), (Sofia University, Bulgaria)
  • Formāts: 240 pages
  • Izdošanas datums: 01-Nov-2024
  • Izdevniecība: CRC Press Inc
  • Valoda: eng
  • ISBN-13: 9781040288511
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  • Formāts: 240 pages
  • Izdošanas datums: 01-Nov-2024
  • Izdevniecība: CRC Press Inc
  • Valoda: eng
  • ISBN-13: 9781040288511
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Kolev (organic chemistry, Plovdiv U., Bulgaria) and Ivanova (analytical chemistry, Sofia U., Bulgaria) offer the first book devoted to the theory and practical application of partially oriented colloidal systems in nematic liquid crystals for infrared spectroscopic and structural elucidation in an embedded chemical in the solid state. Their goal is to indicate the possibilities of new applications of the new orientation technique to characterize the structure of various compounds, particularly oriented compounds. They cover the background of linear-dichroic infrared spectroscopy, the background of the orientation method of colloid suspensions in a nematic host, the structural elucidation of inorganic compounds and glasses, the structural elucidation of organic compounds, and applications in pharmaceutical analysis and the chemistry of dyes. Annotation ©2011 Book News, Inc., Portland, OR (booknews.com)

A technique that is useful in the study of pharmaceutical products and biological molecules, polarization IR spectroscopy has undergone continuous development since it first emerged almost 100 years ago. Capturing the state of the science as it exists today, Linearly Polarized IR Spectroscopy: Theory and Applications for Structural Analysis demonstrates how the technique can be properly utilized to obtain important information about the structure and spectral properties of oriented compounds.

The book starts with the theoretical basis of linear-dichroic infrared (IR-LD) spectroscopy and then moves on to examine the background of the orientation method of colloid suspensions in a nematic host. It explores the orientation procedure itself, experimental design, and mathematical tools for the interpretation of the IR spectroscopic patterns. Next, the authors describe the structural elucidation of inorganic and organic compounds and glasses. Finally, they discuss applications in pharmaceutical analysis and the chemistry of dyes. Filled with more than 140 illustrations along with a color insert, the book explains both the scope of the polarized IR spectroscopy method as well as its limitations.

A powerful source of information not only for specialists in IR spectroscopy, but also for those working in the field of structural analysis, this volume moves the field closer to developing an inherently classical method for the structural characterization of compounds.

Preface vii
Acknowledgments ix
Authors xi
Introduction xiii
Chapter 1 Linear-Dichroic Infrared (IR-LD) Spectroscopy: Background 1(28)
1.1 Theoretical Prerequisites
3(5)
1.2 Symmetry Analysis of Normal Vibrations and Dipole Moments of Transition Generated Therefrom
8(5)
1.2.1 Elements and Operations of Symmetry
8(4)
1.2.2 Symmetry Analysis of the Dipole Moments of Transition
12(1)
1.3 Orientation of the Samples
13(5)
1.3.1 Orientation in Liquid Crystal Solutions
14(3)
1.3.2 Orientation as Suspension in Liquid Crystals
17(1)
1.4 Photometrization and Processing of IR-LD Spectra: Reducing Differential Procedure
18(5)
1.5 Effects in the Infrared Spectra of Crystals
23(6)
Chapter 2 The Background of the Orientation Method of Colloid Suspensions in a Nematic Host 29(17)
2.1 Orientation Procedure
29(7)
2.2 Validation of the Orientation Procedure
36(7)
2.2.1 Accuracy and Repeatability
42(1)
2.2.2 The Quantitative Ratio of Liquid Crystals and Solid Samples
42(1)
2.2.3 Preliminary Rubbing Out of the KBr Plates
43(1)
2.2.4 Peak Function Type for the Curve-Fitting Procedure
43(1)
2.2.5 Number of Scans in the Measurements
43(1)
2.3 Experimental Design
43(3)
2.4 Mathematical Tools for the Interpretation of the IR Spectroscopic Patterns
46(1)
2.4.1 IR Spectra Subtraction
46(1)
2.4.2 The Smoothing Procedure
46(1)
2.4.2.1 Limits of Detection and Smoothing Procedure Validation 46(17)
2.4.3 Accuracy and Precision
48(1)
2.4.4 Deconvolution
48(1)
2.4.5 Curve-Fitting Procedure (CFP)
49(3)
2.4.6 Baseline Correction (BLC)
52(1)
2.5 Reducing-Difference Procedure (RDP) for IR-LD Spectra Interpretation
53(10)
Chapter 3 Structural Elucidation of Inorganic Compounds and Glasses 63(10)
3.1 Inorganic Compounds
63(6)
3.2 IR Spectroscopic Elucidation of Glasses
69(4)
Chapter 4 Structural Elucidation off Organic Compounds 73(50)
4.1 Analysis of Heterocyclic Compounds
73(31)
4.2 Small Biologically Active Molecules
104(19)
Chapter 5 Application in Pharmaceutical Analysis 123(28)
5.1 Analysis of Morphine Alkaloids
143(8)
Chapter 6 Application in the Chemistry of Dyes 151(36)
6.1 Stilbazolium Salts
151(25)
6.2 Dicyanoisophorone Derivatives
176(11)
Appendix: List of Acronyms 187(2)
References 189(24)
Index 213
Bojidarka Ivanova, Ph.D. received her M.Sc. degree in physical and theoretical chemistry in 1997 from Sofia University (St. Kl. Okhridski), Bulgaria. She earned her Ph.D. in analytical chemistry from Sofia University in 2001. Since 2003, Dr. Ivanova has been an associate professor in chemistry, holding the corresponding position at the Department of Analytical Chemistry at Sofia University.

Tsonko Kolev, D.Sc. obtained his M.Sc. degree in chemistry in 1973 at Sofia University (St. Kl. Okhridski), Bulgaria, and his Ph.D. in organic chemistry in 1982 from the Institute of Organic Chemistry, Bulgarian Academy of Sciences. His current position is head of the Department of Organic Chemistry at Plovdiv University (P. Hilendarski), Bulgaria.