Scientists from 30 independent research groups working in Italian universities have contributed to this book on liver pathophysiology. The volume presents selected reviews of the research carried out in the field within the last two years, and covers the most recent achievements. The book will be of great value to all hepatologists and doctors of internal medicine - informing those working in other countries of the latest Italian research on this subject; and helping the members of the research groups to focus their attention on selected topics.
Part 1 Experimental pathophysiology: oxidative damage in the
pathogenesis of liver cirrhosis, M. Parola et al; from ischemic injury to
post-ischemic response - events in the parenchymal liver cells, A.
Bernelli-Zazzera; the anoxic injury in hepatocytes, A. Gasbarrini et al; cell
death and regeneration in liver tissue, R. Mancini et al; membrane fluidity
and liver pathophysiology, D. Alvaro et al; hepatic uptake of organic anions
- different mechanisms and putative membrane carrier proteins, A.M. Torres
and C. Tiribelli; regulation of bile acid synthesis in humans, M. Bertolotti
et al; role of the T cell response to hepatitis B virus (HBV) nucleocapsid
antigen in the pathogenesis of HBV infection, F. Fiaccadori et al. Part 2
Epidemiology and clinical pathophysiology: natural history of chronic HCV
infection, G. Giusti et al; epidemiological aspects of hepatitis C virus
infection in southern Italy, O. Schiraldi; hepatitis C virus and autoimmune
chronic hepatitis, S. Magrin et al; immunodetection of hepatitis C virus
(HCV)-related antigens in tissues - problems and perspectives, D. Sansonno et
al; hormonal regulation of hepatic amino acid conversion into urea, G.
Marchesini et al; extracellular matrix structure and regulation in normal and
fibrotic liver, S. Milani et al. Part 3 Clinical aspects: prognostic and
therapeutic implications of splanchnic hemodynamic evaluation in cirrhosis,
A. Gatta et al; blood pressure and heart rate during liver cirrhosis, F.
Veglio et al; hormone metabolism and liver disease - implications in adrenal,
bone and gonadal pathophysiology, R. Naccarato et al. Part 4 Complications
and therapy in liver diseases: pathogenesis and diagnosis of hepatorenal
syndrome, P. Gentilini et al; effect of interferon alone or after prednisone
withdrawal in children with chronic hepatitis B, R. Utili et al; clinical
management of primary biliary cirrhosis, M. Podda et al; efficacy of
surveillance programs of cirrhotic patients in the early diagnosis and
treatment of HCC, L. Bolondi et al; the natural history of hepatocellular
carcinoma, G. Covini et al; surgical approach to portal hypertension, G.P.
Spina et al; orthotopic liver transplantation for chronic viral hepatitis -
the Turin experience, M. Badini et al; the role of endotoxin in liver
disease, D. Scevola et al.
