This book presents the technological advances in the field of mass spectrometry-based approaches for treating human diseases and diagnostics as well as the application of such approaches to study, in depth, human diseases, biomarkers discovery and validation, and to provide mechanistic insights of potential new therapeutics. This is an ideal book for students, technicians, researchers, and medical doctors that work in the field of mass spectrometry and proteomics
Preface.- Isolation of Extracellular Vesicles Using Titanium Dioxide
Microspheres.- Glycosort: a computational solution to post-process
quan-titative large-scale intact glycopeptide analyses.- Applications of Mass
Spectrometry in the Characterization, Screening, Diagnosis, and Prognosis of
COVID-19.- Proteomics and Metabolomics in Congenital Zika Syndrome: A Review
of Molecular Insights and Biomarker Discovery.- Mass Spectrometry
Applications to Study Human Microbiome.- Neuroproteomics: unveiling the
molecular insights of psychiatric disorders with a focus on anxiety disorder
and depression.- Proteomic-based studies on memory formation in normal and
neurodegenerative diseases affected brains.- Cardioproteomics: insights on
cardiovascular diseases.- Kidney Disease and Proteomics: A Recent Overview of
a Useful Tool for Improving Early Diagnosis.- Multi-omics investigations in
endocrine systems and their clinical implications.- Omics to Unveil Diabetes
Mellitus Pathogenesis and Biomarkers: Focus on Proteomics, Lipidomics and
Metabolomics.- Proteomics: Unraveling the Crosstalk Between Innate Immunity
and Disease Pathophysiology, Diagnostics, and Treatment Options.-
Applications of Proteomics in Probiotics having Anticancer and
Chemo-preventive Properties.- Mass spectrometry-based characterization of
protein aggregates in tissues and biofluids.- Index.
Dr. Thiago Verano-Braga is an Associate Professor in the Department of Physiology and Biophysics at the Federal University of Minas Gerais (UFMG) in Brazil.