A survey of the current literature on medicinal uses of tropical plants, detailing the drug discovery work of major pharmaceutical companies as well as smaller-scale regional efforts. Discusses habitat protection, ethical issues and intellectual property rights, and the practical aspects of natural products chemistry, in sections on biodiversity prospecting, drug development, and conservation; and country and regional programs in medicinal plant research and health care. Includes guidelines for plant collections. Annotation c. by Book News, Inc., Portland, Or.
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This book opens readers' eyes to the enormous resources of the Earth's rain forests and the potential impact of their destruction in terms of human health.
Foreword ix Norman R. Farnsworth Preface xi Acknowledgments xv PART ONE Biodiversity Prospecting, Drug Development, and Conservation 1(230) Natural Products and Medicine: An Overview 3(8) Varro E. Tyler Biological Diversity, Chemical Diversity, and the Search for New Pharmaceuticals 11(8) James D. McChesney Development of Pharmaceutical Companies Based on Plant Products: Suggested Approaches 19(22) Douglas Davidson Peter J. Hylands William Rod Sharp Roy W. Stahlhut Chemical Approaches to the Study of Ethnomedicines 41(7) Domingos Savio Nunes The Contribution of the Physician to Medicinal Plant Research 48(15) Douglas C. Daly Charles F. Limbach Conservation and Tropical Medicinal Plant Research 63(12) Steven R. King Higher Plants Versus Microorganisms: Their Future in Pharmaceutical Research 75(3) Georg Albers-Schonberg Topotecan Development: An Example of the Evolution of Natural Product Drug Discovery Research 78(16) Brad K. Carte Randall K. Johnson Shaman Pharmaceuticals Approach to Drug Development 94(7) Lisa A. Conte Drug Discovery and Development at the National Cancer Institute: The Role of Natural Products of Plant Origin 101(36) Gordon M. Cragg Michael R. Boyd The Merck/INBio Agreement: A Pharmaceutical Company Perspective 137(5) Lynn Helena Caporale Biodiversity Prospecting 142(32) Walter V. Reid Sarah A. Laird Carrie A. Meyer Rodrigo Gamez Ana Sittenfeld Daniel Janzen Michael A. Gollin Calestous Juma Property Rights and Genetic Resources: A Framework for Analysis 174(17) Jack R. Kloppenburg Jr. Michael J. Balick Monetizing the Pharmacological Benefits of Plants 191(28) Peter P. Principe Capturing the Pharmaceutical Value of Species Information: Opportunities for Developing Countries 219(12) Bruce A. Aylward PART TWO Country and Regional Programs in Medicinal Plant Research and Health Care 231(178) Resource Utilization and Conservation of Biodiversity in Africa 233(18) Maurice M. Iwu The Economic Value and Potential for Plant-Derived Pharmaceuticals from Ghana 251(10) G. T. Odamtten E. Laing D. K. Abbiw The Rwanda Experience in Enhancing and Commercializing the Use of Traditional Medicinal Plants 261(5) Luc Van Puyvelde The Role of Medicinal Plants in Health Care in India 266(12) James A. Duke A Standardized Commiphora wightii Preparation for Management of Hyperlipidemic Disorders 278(6) B. N. Dhawan Plant Explorations in Asia Under the Sponsorship of the National Cancer Institute, 1986-1991: An Overview 284(27) Djaja Doel Soejarto Charlotte Gyllenhaal Peter S. Ashton S. H. Sohmer Medicinal Plants of Mexico: A Program for Their Scientific Validation 311(6) Xavier Lozoya, M.D. TRAMIL: A Research Project on the Medicinal Plant Resources of the Caribbean 317(9) Lionel Robineau Djaja Doel Soejarto Ethnopharmacological Studies and Biological Conservation in Belize 326(8) Michael J. Balick Rosita Arvigo Gregory Shrophshire Robert Mendelsohn Tropical Medicinal Plant Conservation and Development Projects: The Case of the Costa Rican National Institute of Biodiversity (INBio) 334(7) Ana Sittenfeld FENAMADs Program in Traditional Medicine: An Integrated Approach to Health Care in the Peruvian Amazon 341(25) Miguel N. Alexiades Didier Lacaze D. Environment, Society, and Disease: The Response of Phytotherapy to Disease Among the Warao Indians of the Orinoco Delta 366(20) Werner Wilbert Medicinal Plant Research in Brazil: Data from Regional and National Meetings 386(16) Alba R. M. Souza Brito Antonio A. Souza Brito Community Ethnobotany: Setting Foundations for an Informed Decision on Trading Rain Forest Resources 402(7) Elaine Elisabetsky Appendix: Manual for Plant Collections 409(12) Elaine Elisabetsky Rachel Trajber Lin Chao Ming Epilogue 421(2) Richard Deertrack List of Contributors 423(4) Index 427
Michael J. Balick is director and philecology curator at the New York Botanical Garden Institute of Economic Botany, and adjunct professor in forestry at Yale University and the City University of New York. Elaine Elisabetsky is professor at the Laboratorio de Ethnofarmacologia, Universidade Federal do Rio Grande do Sul in Brazil. Saraah A. Laird is research fellow at the Rainforest Alliance, and former director of the Rainforest Alliance's Periwinkle Project.
