A thorough updating of the best-selling, vital reference and textbook on melanocytic proliferations
PRAISE FOR THE FIRST EDITION:
Well-written and entertaining Modern Pathology
An extremely helpful guide for the practicing dermatopathologist or general pathologist Archives of Pathology and Laboratory Medicine
An incredibly relevant clinical-histopathologic text Doodys
Melanocytic proliferations comprise a large number of pigmented lesions of the skin and muscosa. Of these, melanoma is of particular interest to clinicians and their patients. The rising number of incidences of melanoma has led to increased interest in the disease from diagnostic, management, and basic science perspectives.
The Melanocytic Proliferations: A Comprehensive Textbook of Pigmented Lesions is the most complete single-source treatment of the subject availablethoroughly updated to reflect the very latest studies and clinical experience in diagnosing and treating melanocytic proliferation. This new edition of the bestseller presents an experience- and evidence-based review of pigmented lesions that encompasses the biology, diagnosis, and treatment of melanocytic proliferations and disorders, including melanoma. It comes with over 300 new color imagesbringing the total to over 600and contains two completely new chapters: Dermatoscopic Diagnosis of Melanoma; and Reflectance Confocal Microscopy.
Chapter coverage includes: An approach to the clinical diagnosis of melanoma, its precursors, and its clinical mimics Freckles and lentigines Benign acquired nevi Dermal dendritic melanocytic proliferations/dermal melanocytoses Spitz nevus Combined nevus, deep penetrating nevus, plexiform spindle cell nevus, and borderline tumors of the deep penetrating nevus variant Recurrent melanocytic nevus Congenital nevi Dysplastic melanocytic nevi, de novo intradermal epithelioid and lentiginous melanocytic dysplasias, and nevi at specific anatomic sites Melanoma Conjunctival melanocytic proliferations Use of adjunctive immunoperoxidase, molecular, and ultrastructural studies in the diagnosis of melanocytic proliferations Biology of melanoma Borderline melanocytic proliferation Dermatoscopic diagnosis of melanoma Reflectance confocal microscopy Therapy of melanoma
The Melanocytic Proliferations: A Comprehensive Textbook of Pigmented Lesions is an incredibly important text for all clinical pathologists, dermatopathologists, surgical pathologists, dermatologists, cosmetic physicians, and surgeons.
| Dedication |
|
vii | |
| Preface |
|
viii | |
| Disclosure |
|
ix | |
| About the Companion Website |
|
x | |
|
1 An Approach to the Clinical Diagnosis of Melanoma, Its Precursors, and Its Clinical Mimics |
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|
1 | (43) |
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2 Freckles and Lentigines |
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|
44 | (21) |
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|
|
65 | (20) |
|
4 Dermal Dendritic Melanocytic Proliferations/Dermal Melanocytoses |
|
|
85 | (22) |
|
|
|
107 | (57) |
|
6 Combined Nevus, Deep Penetrating Nevus, Plexiform Spindle Cell Nevus, and Borderline Tumors of the Deep Penetrating Nevus Variant |
|
|
164 | (11) |
|
7 Recurrent Melanocytic Nevus |
|
|
175 | (12) |
|
|
|
187 | (14) |
|
9 Dysplastic Melanocytic Nevi, De Novo Intradermal Epithelioid and Lentiginous Melanocytic Dysplasias, and Nevi at Specific Anatomic Sites |
|
|
201 | (53) |
|
|
|
254 | (111) |
|
11 Conjunctival Melanocytic Proliferations |
|
|
365 | (15) |
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12 Use of Adjunctive Immunoperoxidase, Molecular, and Ultrastructural Studies in the Diagnosis of Melanocytic Proliferations |
|
|
380 | (32) |
|
|
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412 | (31) |
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14 Borderline Melanocytic Proliferation |
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443 | (24) |
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15 Dermatoscopic Diagnosis of Melanoma |
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|
467 | (7) |
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16 Reflectance Confocal Microscopy |
|
|
474 | (14) |
|
|
|
488 | (22) |
| Index |
|
510 | |
Cynthia M. Magro, MD, is Professor of Pathology and Director of Dermatopathology at Weill Medical College of Cornell University in New York City. She has published extensively in the areas of inflammatory skin disease, including collagen vascular disease, vasculitis, cutaneous manifestations of systemic disease, and unique drug hypersensitivity reactions. A significant focus of her work has been lymphocytic infiltrates, including unique forms of drug reactions such as the interstitial granulomatous drug reaction and drug-associated reversible T cell dyscrasia; prelymphomatous cutaneous lymphoid dyscrasias including atypical lymphocytic lobular panniculitis pityriasis lichenoides chronica and pigmented purpuric dermatosis; and malignant T and B cell lymphomas. She has extended her work in immune mechanisms of skin disease and applied it to areas of lung transplantation and pulmonary fibrosis.
Neil Crowson, MD, is Clinical Professor of Dermatology, Pathology, and Surgery, and Director of Dermatopathology at the University of Oklahoma and Regional Medical Laboratory in Tulsa, Oklahoma. His current research interests focus on mechanisms of neoplastic and inflammatory skin disease.
Martin C. Mihm, Jr., MD, is Clinical Professor of Pathology and Dermatology at Harvard Medical School, Massachusetts General Hospital. He is internationally recognized for his expertise in the pathology, diagnosis, and management of pigmented lesions, lymphoid disorders, and vascular tumors. He has worked extensively to understand the host response to melanoma and other tumors. He has served as codirector of the WHO Melanoma Program in addition to his many obligations in translational and clinical research in cutaneous inflammation, tumor vaccination, and pathogenesis of vascular lesions in children.
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