The present book discusses about the inherent need of the metal ions in metabolic reactions. It covers all the essential elements and their mechanistic prospect to regulate the biological reactions, in detail. It discusses broad domain of elements including main group as well as transition elements in a comparative and comprehensive manner.
This book discusses the inherent need for and significance of metal ions in metabolic reactions. It details their essential elements and mechanistic prospects in regulating biological reactions, as well as covers the broad domain of elements, including main group as well as transition elements, in a comparative and comprehensive manner. Contemporary and advanced topics, such as nuclear medicine and biomineralization, are also covered.
Features:
- Highlights the different behaviors of Fe/Cu proteins and the structural changes during their biological functioning
- Discusses the mechanistic prospects of various enzymes and proteins, e.g., Cu-Zn SOD, zinc finger, and ionophores
- Explores the chemical and biological prospects of trace and ultra-trace elements
- Includes biomimetic models of iron and copper
- Reviews the criteria for nature selecting metal ions, why only certain elements are essential, and the differences between biologically induced and biologically controlled biomineralization
This book is aimed at graduate students and researchers in chemical engineering, materials science, chemistry, and biological sciences.
1. Role of Metal Ions in Biology: An overview
2. Basic Principles of Coordination Chemistry
3. Biochemistry of Alkali and Alkaline Earth Metals
4. Biological Relevance of Iron: Uptake, Electron Transfer and Transport
5. Role of Cobalt in Biology
6. Biochemistry of Nickel
7. Bioinorganic Prospect of Copper Containing Enzymes
8. Biochemistry of Zinc
9. Metal Ions in Diagnostics and Therapeutics
10. Biomineralization
Adish Tyagi works as Scientific Officer-E in the Chemistry Division, Bhabha Atomic Research Centre (BARC), India. He pursued his post-graduation in Chemistry from Delhi University, India, and obtained his Ph.D. degree in Chemistry from Homi Bhabha National Institute, India. He has published several research papers in peer-reviewed journals and 4 book chapters. He has been awarded CSIR-JRF fellowship and DAE-Young Applied Scientist and Technologist Award (2021). His research interests include synthesis of organometallic molecular precursors for technologically important nanomaterials, development of efficient phosphor for white light emission and purification of strategic materials.
Rohit Singh Chauhan works as Assistant Professor at K. J. Somaiya College of Science and Commerce, India. He pursued his post-graduation in Chemistry from Christ Church P. G. College, India and was awarded Ph.D. degree from Homi Bhabha National Institute Deemed University, India. He has several international peer reviewed papers to his credit and was also awarded the Dr. S. K. Somaiya Award for Excellence in Research-Higher and Technical Education. His research interests include synthetic inorganic chemistry, organometallics and catalysis.
A.K. Tyagi is Associate Director at the Chemistry Group, Bhabha Atomic Research Centre, India and Senior Professor of Chemistry at Homi Bhabha National Institute, India. He obtained his M.Sc. (Chemistry) from Meerut University, India and was awarded a Ph.D. degree by Mumbai University, India. He has published more than 600 papers in journals, several books and has supervised 30 PhD students. He also holds several awards for his contribution to chemistry including the Dr. Lakshmi Award by the Indian Association of Solid State Chemists and Allied Scientists (2001), Rheometric Scientific-Indian Thermal Analysis Society Award (2002), and Gold Medal of Indian Nuclear Society (2003). His research interests lie in the chemistry of materials, including functional materials, nanomaterials, nuclear materials, metastable materials, hybrid materials, and structure-property correlation.
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