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MKSAP 16 Print: Medical Knowledge Self-Assessment Program: Parts A and B [Mīkstie vāki]

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  • Formāts: Paperback / softback
  • Izdošanas datums: 01-Sep-2012
  • Izdevniecība: American College of Physicians
  • ISBN-10: 1938245008
  • ISBN-13: 9781938245008
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  • Formāts: Paperback / softback
  • Izdošanas datums: 01-Sep-2012
  • Izdevniecība: American College of Physicians
  • ISBN-10: 1938245008
  • ISBN-13: 9781938245008
Citas grāmatas par šo tēmu:
The 16th edition of Medical Knowledge Self-Assessment Program (MKSAP(R) 16) is specifically intended for physicians who provide personal, nonsurgical care to adults. Included are: general internists and primary care physicians; subspecialists who need to remain up-to-date in internal medicine; residents preparing for the Certification Exam in internal medicine; physicians preparing for the Maintenance of Certification Exam in internal medicine. The learning objectives of MKSAP(R) 16 are to: Close gaps between actual care in your practice and preferred standards of care, based on best evidence. Diagnose disease states that are less common and sometimes overlooked and confusing. Improve management of comorbid conditions that can complicate patient care. Determine when to refer patients for surgery or care by subspecialists. Pass the ABIM Certification Examination and the ABIM Maintenance of Certification Examination. MKSAP(R) 16 Print includes 11 highly informative sections and a Cumulative Index. Sections in Part A cover Cardiovascular Medicine; Dermatology; Gastroenterology and Hepatology; Hematology and Oncology; Neurology; Rheumatology Sections in Part B cover Endocrinology and Metabolism; General Internal Medicine; Infectious Disease; Nephrology; Pulmonary and Critical Care Medicine. This option is ideal for those who like to work from a book but need them to be lightweight enough to be portable.
Approach to the Patient with Dermatologic Disease 1(1)
Therapeutic Principles in Dermatology
Topical Corticosteroids
2(2)
Treatment of Dermatologic Conditions in Pregnancy
4(1)
Common Rashes
Eczematous Dermatoses
5(5)
Contact Dermatitis
5(1)
Hand Dermatitis
6(1)
Xerotic Eczema
7(1)
Nummular Dermatitis
7(1)
Stasis Dermatitis
7(1)
Atopic Dermatitis
8(2)
Papulosquamous Dermatoses
10(4)
Psoriasis
10(1)
Lichen Planus
11(2)
Pityriasis Rosea
13(1)
Seborrheic Dermatitis
14(1)
Drug Reactions
14(2)
Pigmented Purpuric Dermatoses
16(1)
Miliaria
17(1)
Acantholytic Dermatosis (Grover Disease)
17(1)
Acneiform Eruptions
Acne
18(3)
Rosacea
21(1)
Hidradenitis Suppurativa
22(1)
Common Skin and Nail Infections
Bacterial Skin Infections
22(4)
Folliculitis
22(1)
Abscesses/Furuncles/Carbuncles
23(1)
Impetigo
23(1)
Cellulitis and Erysipelas
24(1)
Erythrasma
25(1)
Keratolysis
25(1)
Superficial Fungal Infections
26(1)
Tinea
26(1)
Candidiasis
27(1)
Viral Skin Infections
27(4)
Herpes Simplex Virus
27(2)
Herpes Zoster
29(1)
Warts
30(1)
Molluscum Contagiosum
31(1)
Stings and Bites
Scabies Infestation
31(1)
Lice
32(1)
Bedbugs
32(1)
Spider Bites
32(1)
Cuts, Scrapes, and Burns
Cuts and Scrapes
33(1)
Burns
34(1)
Common Neoplasms
Basal Cell Carcinoma
34(1)
Actinic Keratoses and Squamous Cell Carcinoma In Situ
35(1)
Squamous Cell Carcinoma
36(1)
Keratoacanthoma
37(1)
Malignant Melanoma
37(2)
Seborrheic Keratoses
39(1)
Melanocytic Nevi
39(1)
Dysplastic Nevi
39(1)
Halo Nevi
40(1)
Sebaceous Hyperplasia
40(1)
Neurofibromas
40(1)
Acrochordons (Skin Tags)
40(1)
Cherry Hemangiomas
41(1)
Dermatofibromas
41(1)
Solar Lentigines
41(1)
Hypertrophic Scars and Keloids
41(1)
Pyogenic Granulomas
41(1)
Epidermal Inclusion Cysts
41(1)
Lipomas
42(1)
Pruritus
42(2)
Urticaria
Causes
44(1)
Clinical Manifestations and Diagnosis
44(1)
Treatment
45(1)
Autoimmune Bullous Diseases
Recognizing and Diagnosing Autoimmune Bullous Diseases
46(2)
Treatment
48(1)
Disease Associations
48(1)
Cutaneous Manifestations of Internal Disease
Rheumatology
48(5)
Lupus Erythematosus
48(2)
Dermatomyositis
50(1)
Livedo Reticularis
51(1)
Purpura and Cutaneous Vasculitis
51(2)
Rheumatoid Arthritis
53(1)
Nephrology
53(1)
Pruritus
53(1)
Calciphylaxis
53(1)
Nephrogenic Systemic Fibrosis
54(1)
Cutaneous Malignancies Following Kidney Transplantation
54(1)
Pulmonology
54(1)
Sarcoidosis
54(2)
Erythema Nodosum
55(1)
Gastroenterology
56(1)
Inflammatory Bowel Disease
56(2)
End-Stage Liver Disease
57(1)
Hematology/Oncology
58(2)
Sweet Syndrome
58(2)
Endocrinology
60(1)
Diabetes Mellitus
60(1)
Thyroid Disease
61(1)
Infectious Disease
61(1)
HIV Infection
61(1)
Dermatologic Urgencies and Emergencies
Erythema Multiforme, Stevens-Johnson Syndrome, and Toxic Epidermal Necrolysis
61(3)
Diagnosis
63(1)
Treatment
63(1)
Erythroderma
64(1)
Diagnosis
65(1)
Treatment
65(1)
Hair Disorders
Overview
65(1)
Nonscarring Alopecias
66(1)
Metabolic Imbalance and Medications
66(1)
Androgenetic Alopecia
66(1)
Alopecia Areata
66(1)
Telogen Effluvium
66(1)
Scarring Alopecias
66(1)
Traction Alopecia
66(1)
Central Centrifugal Cicatricial Alopecia
66(1)
Lichen Planopilaris
67(1)
Lupus
67(1)
Nail Disorders
Psoriatic Nail Changes
67(1)
Lichen Planus
68(1)
Melanonychia and Subungual Melanoma
68(1)
Beau Lines
68(1)
Median Nail Dystrophy
69(1)
Onychomycosis
69(1)
Onychogryphosis
69(1)
Disorders of Mucous Membranes
Oral Melanotic Macule
70(1)
Lichen Planus
70(1)
Aphthous Ulcers
70(1)
Leukoplakia and Erythroplakia
71(1)
Actinic Cheilitis
71(1)
Black Hairy Tongue
71(1)
Squamous Cell Carcinoma
72(1)
Oral Candidiasis
72(1)
Foot and Leg Ulcers
Venous Stasis Ulcers
72(1)
Arterial Ulcers
73(1)
Neuropathic Ulcers
74(1)
Skin in Aging Populations
Common Clinical Problems in Older Skin
74(1)
Care of Aged Skin
75(1)
Dermatologic Diseases of Skin of Color
Postinflammatory Hypo- or Hyperpigmentation
76(1)
Common Lesions in Skin of Color
76(1)
Keloids
76(1)
Pseudofollicular Barbae
77(1)
Acne Keloidalis Nuchae
77(1)
Dermatosis Papulosa Nigra
77(1)
Skin Cancers
77(1)
Vitiligo
77
Bibliography 78(3)
Self-Assessment Test 81(56)
Index 137
Approach to the Patient with Rheumatic Disease
Inflammatory Versus Noninflammatory Pain
1(1)
The Musculoskeletal Examination
1(1)
Arthritis
2(1)
Monoarticular Arthritis
2(1)
Oligoarthritis
2(1)
Polyarthritis
2(1)
Extra-Articular Manifestations of Rheumatic Disease
3(3)
Dermatologic Manifestations
3(1)
Fever
3(1)
Inflammatory Eye Disease
3(1)
Lung Disease
4(1)
Diarrhea
5(1)
Musculoskeletal and Rheumatic Manifestations
5(1)
Laboratory Studies
6(1)
Tests That Measure Inflammation
6(1)
Antibody Tests
6(1)
Imaging Studies
7(1)
Radiography
7(1)
CT and MRI
8(1)
Ultrasonography
8(1)
Joint Aspiration
8(1)
Principles of Therapeutics
Evaluation of Disease Progression
9(1)
Anti-Inflammatory Agents
9(2)
NSAIDs
9(1)
Analgesics
10(1)
Colchicine
10(1)
Corticosteroids
10(1)
Disease-Modifying Antirheumatic Drugs
11(3)
Nonbiologic Disease-Modifying Antirheumatic Drugs
11(1)
Biologic Disease-Modifying Antirheumatic Drags
12(2)
Urate-Lowering Therapy
14(1)
Allopurinol
15(1)
Febuxostat
15(1)
Probenecid
15(1)
Uricase
15(1)
Rheumatoid Arthritis
Pathophysiology and Risk Factors
15(1)
Genetic Factors
15(1)
Hormones
16(1)
Antibodies
16(1)
Environmental Factors
16(1)
Diagnosis
16(2)
Clinical Manifestations
16(1)
Evaluation
16(2)
Complications and Extra-Articular Manifestations
18(1)
Management
19(2)
NSAIDs and Corticosteroids
20(1)
Disease-Modifying Antirheumatic Drugs
20(1)
Surgical Therapy
21(1)
Nonpharmacologic Management
21(1)
Rheumatoid Arthritis and Pregnancy
21(1)
Osteoarthritis
Pathophysiology
22(1)
Risk Factors
22(1)
Clinical Features and Classification
22(2)
Primary Osteoarthritis
23(1)
Secondary Osteoarthritis
23(1)
Erosive Osteoarthritis
23(1)
Diffuse Idiopathic Skeletal Hyperostosis
23(1)
Diagnosis
24(1)
Imaging Studies
24(1)
Management
24(2)
Nonpharmacologic Interventions
24(1)
Pharmacologic Therapy
25(1)
Intra-articular Injection
25(1)
Surgical Intervention
25(1)
Fibromyalgia
Epidemiology
26(1)
Evaluation and Diagnosis
26(1)
Treatment
27(1)
Nonpharmacologic Therapy
27(1)
Pharmacologic Therapy
27(1)
Spondyloarthritis
Pathophysiology
28(1)
Genetic Predisposition
28(1)
Environmental Triggers
28(1)
Classification
28(3)
Ankylosing Spondylitis
29(1)
Psoriatic Arthritis
30(1)
Inflammatory Bowel Disease-Associated Arthritis
30(1)
Reactive Arthritis
30(1)
Diagnosis
31(2)
Laboratory Studies
32(1)
Imaging Studies
32(1)
Treatment
33(2)
Axial Involvement
33(1)
Peripheral Involvement
34(1)
Reactive Arthritis
34(1)
Systemic Lupus Erythematosus
Pathophysiology
35(1)
Epidemiology
35(1)
Clinical Manifestations
35(3)
Mucocutaneous Manifestations
35(1)
Musculoskeletal Manifestations
35(1)
Kidney Manifestations
36(1)
Neurologic Manifestations
36(1)
Cardiovascular Manifestations
37(1)
Pulmonary Manifestations
37(1)
Hematologic Manifestations
37(1)
Gastrointestinal Manifestations
37(1)
Malignancy
38(1)
Diagnosis
38(2)
Differential Diagnosis
39(1)
Treatment
40(1)
Reproductive Issues
40(1)
Prognosis
41(1)
Systemic Sclerosis
Pathophysiology and Epidemiology
41(1)
Classification
41(1)
Diagnosis
41(1)
Clinical Manifestations and Management
42(3)
Cutaneous Manifestations
42(1)
Musculoskeletal Manifestations
43(1)
Vascular Manifestations
43(1)
Gastrointestinal Manifestations
43(1)
Kidney Manifestations
43(1)
Pulmonary Manifestations
44(1)
Cardiac Manifestations
44(1)
Scleroderma Spectrum Disorders
45(1)
Pregnancy and Systemic Sclerosis
45(1)
Sjogren Syndrome
Epidemiology and Pathophysiology
46(1)
Clinical Manifestations
46(1)
Diagnosis
46(1)
Treatment
46(1)
Prognosis
47(1)
Mixed Connective Tissue Disease
Clinical Manifestations
47(1)
Diagnosis
48(1)
Treatment and Prognosis
48(1)
Crystal-Induced Arthropathies
Gout
48(4)
Epidemiology
48(1)
Pathophysiology
48(2)
Clinical Manifestations
50(1)
Diagnosis
50(1)
Treatment
51(1)
Calcium Pyrophosphate Deposition Disease
52(2)
Epidemiology and Pathophysiology
52(1)
Clinical Manifestations
53(1)
Diagnosis
53(1)
Treatment
53(1)
Basic Calcium Phosphate Deposition Disease
54(1)
Infectious Arthritis
Diagnosis
54(1)
Clinical Manifestations and Physical Examination
54(1)
Laboratory and Radiographic Studies
54(1)
Common Causes
55(2)
Infection with Gram-Positive Organisms
55(1)
Infection with Gram-Negative Organisms
55(1)
Lyme Arthritis
56(1)
Mycobacterial Infections
56(1)
Fungal Infections
56(1)
Viral Infections
56(1)
Prosthetic Joint Infections
57(1)
Infections in Previously Damaged Joints
57(1)
Management
57(1)
Pharmacologic Therapy
57(1)
Surgical Management
58(1)
Idiopathic Inflammatory Myopathies
Pathophysiology
58(1)
Epidemiology
58(1)
Clinical Manifestations
59(1)
Muscular Manifestations
59(1)
Cutaneous Manifestations
59(1)
Extramuscular Manifestations
59(1)
Cardiopulmonary Manifestations
60(1)
Gastrointestinal Manifestations
60(1)
Diagnosis
60(1)
Muscle-Related Enzymes
60(1)
Autoantibodies
60(1)
Imaging Studies
61(1)
Electromyography
61(1)
Muscle Biopsy
61(1)
Differential Diagnosis
61(1)
Treatment
62(1)
Association with Malignancy
62(1)
Prognosis
62(2)
Systemic Vasculitis
Large-Vessel Vasculitis
64(2)
Giant Cell Arteritis
64(1)
Polymyalgia Rheumatica
65(1)
Takayasu Arteritis
65(1)
Medium-Sized Vessel Vasculitis
66(1)
Polyarteritis Nodosa
66(1)
Kawasaki Disease
66(1)
Small-Vessel Vasculitis
67(3)
Antineutrophil Cytoplasmic Antibodies and Associated Vasculitis
67(2)
Cryoglobulinemic Vasculitis
69(1)
Henoch-Schonlein Purpura
69(1)
Cutaneous Leukocytoclastic Vasculitis
69(1)
Other Systemic Inflammatory Diseases
Behcet Disease
70(1)
Clinical Manifestations and Diagnosis
71(1)
Treatment
71(1)
Relapsing Polychondritis
71(1)
Clinical Manifestations
71(1)
Diagnosis
72(1)
Treatment
72(1)
Adult-Onset Still Disease
72(1)
Clinical Manifestations
72(1)
Diagnosis
73(1)
Treatment
73(1)
Familial Autoinflammatory Diseases
73(1)
Diseases of Collagen
73(1)
Osteogenesis Imperfecta
73(1)
Ehlers-Danlos Syndrome
73(1)
Marfan Syndrome
74(1)
Sarcoidosis
74
Clinical Manifestations
75(1)
Diagnosis
75(1)
Treatment
75
Bibliography 75(4)
Self-Assessment Test 79(72)
Index 151
Epidemiology of Cardiovascular Disease
Overview
1(1)
Ethnicity and Cardiovascular Disease
1(1)
Chronic Kidney Disease and Cardiovascular Disease
2(1)
Systemic Inflammatory Conditions and Cardiovascular Disease
2(1)
Quality Measures in Cardiovascular Disease
3(1)
Diagnostic Testing in Cardiology
Clinical History and Physical Examination
3(1)
Diagnostic Testing for Atherosclerotic Coronary Disease
3(6)
Cardiac Stress Testing
3(5)
Viability Testing
8(1)
Visualization of die Coronary Anatomy
8(1)
Coronary Artery Calcium Scoring
8(1)
Risks of Coronary Diagnostic Testing
8(1)
Diagnostic Testing for Structural Heart Disease
9(2)
Diagnostic Testing for Cardiac Arrhythmias
11(1)
Coronary Artery Disease
Risk Factors for Coronary Artery Disease
12(2)
Established Risk Factors
12(1)
Emerging Risk Factors
13(1)
Chronic Stable Angina
14(5)
Diagnosis and Evaluation
14(1)
Medical Therapy
14(3)
Coronary Revascularization
17(1)
Follow-up Care
18(1)
Acute Coronary Syndromes
19(9)
Clinical Presentation and Classification
19(1)
Non-ST-Elevation Myocardial Infarction and Unstable Angina
20(2)
ST-Elevation Myocardial Infarction
22(6)
Coronary Artery Disease in Patients with Diabetes Mellitus
28(1)
Diagnostic Issues
28(1)
Invasive Approaches
29(1)
Pharmacologic Treatment and Secondary Prevention
29(1)
Women and Cardiovascular Disease
29(1)
Epidemiology
29(1)
Clinical Presentation
30(1)
Evaluation
30(1)
Risk Reduction
30(1)
Heart Failure
Diagnosis and Evaluation of Heart Failure
30(2)
Clinical Evaluation
30(1)
Diagnostic Testing
31(1)
Laboratory Evaluation
32(1)
Evaluation for Ischemia
32(1)
Medical Therapy for Systolic Heart Failure
32(3)
ACE Inhibitors and Angiotensin Receptor Blockers
33(1)
β-Blockers
33(1)
Initiating and Managing ACE Inhibitor and β-Blocker Therapy
34(1)
Diuretics
34(1)
Digoxin
34(1)
Aldosterone Antagonists
34(1)
Hydralazine and Isosorbide Dinitrate
34(1)
Calcium Channel Blockers
35(1)
Heart Failure With Preserved Ejection Fraction
35(1)
Device Therapy
36(1)
Implantable Cardioverter-Defibrillator for Prevention of Sudden Cardiac Death
36(1)
Cardiac Resynchronization Therapy
36(1)
Follow-up Management of Chronic Heart Failure
37(1)
Serial Assessment
37(1)
Assessing Prognosis
37(1)
Inpatient Management of Heart Failure
37(2)
Acute Decompensated Heart Failure
37(1)
Cardiogenic Shock
38(1)
Strategies to Prevent Readmission
39(1)
Advanced Refractory Heart Failure
39(1)
Mechanical Circulatory Support
39(1)
Management of Posttransplant Patients
40(1)
Specific Cardiomyopathies
40(1)
Takotsubo Cardiomyopathy
40(1)
Acute Myocarditis
40(1)
Tachycardia-Mediated Cardiomyopathy
41(1)
Giant Cell Myocarditis
41(1)
Myocardial Disease
Hypertrophic Cardiomyopathy
41(5)
Clinical Presentation and Diagnosis
41(2)
Clinical Course and Risk Stratification
43(1)
Management
43(3)
Restrictive Cardiomyopathy
46(1)
Clinical Presentation and Evaluation
46(1)
Management
46(1)
Cardiac Tumors
47(1)
Tumor Types
47(1)
Clinical Presentation and Evaluation
47(1)
Management
48(1)
Arrhythmias
Approach to die Patient with Bradycardia
48(2)
Clinical Presentation
48(1)
Sinus Bradycardia
48(1)
Atrioventricular Block
49(1)
Pacemakers
49(1)
Approach to the Patient With Tachycardia
50(2)
Evaluation
50(1)
Antiarrhythmic Medications
51(1)
Atrial Fibrillation and Atrial Flutter
52(3)
Clinical Presentation
52(1)
Acute Management
53(1)
Long-term Management
53(2)
Atrial Flutter
55(1)
Supraventricular Tachycardias
55(2)
Clinical Presentation
55(1)
Atrioventricular Nodal Reentrant Tachycardia
56(1)
Atrioventricular Reciprocating Tachycardia
56(1)
Premature Atrial Contractions and Atrial Tachycardia
57(1)
Ventricular Arrhythmias
57(1)
Premature Ventricular Contractions
57(1)
Ventricular Tachycardia with Structural Heart Disease
57(1)
Idiopathic Ventricular Tachycardia
57(1)
Inherited Arrhythmia Syndromes
58(2)
Sudden Cardiac Arrest
60(1)
Epidemiology
60(1)
Acute Management
60(1)
Device Therapy for Prevention of Sudden Death
61(1)
Device Infection
61(1)
Pericardial Disease
Pericarditis
61(6)
Clinical Presentation
61(4)
Evaluation
65(1)
Management
65(2)
Pericardial Effusion Without Cardiac Compression
67(1)
Clinical Presentation and Evaluation
67(1)
Management
68(1)
Cardiac Tamponade
68(1)
Clinical Presentation and Evaluation
68(1)
Management
68(1)
Constrictive Pericarditis
69(1)
Clinical Presentation and Evaluation
69(1)
Management
70(1)
Valvular Heart Disease
Pathophysiology of Valvular Heart Disease
70(1)
Diagnostic Evaluation
71(4)
History and Physical Examination
71(1)
Laboratory and Imaging Tests
71(4)
General Principles of Management of Valvular Disease
75(2)
Aortic Stenosis
77(1)
Pathophysiology and Natural History
77(1)
Management
77(1)
Aortic Regurgitation
78(1)
Pathophysiology and Natural History
78(1)
Management
78(1)
Bicuspid Aortic Valve
78(1)
Mitral Stenosis
79(1)
Pathophysiology and Natural History
79(1)
Management
79(1)
Mitral Regurgitation
80(1)
Pathophysiology and Natural History
80(1)
Management
80(1)
Tricuspid Valve Disease
80(1)
Infective Endocarditis
81(1)
Diagnosis and Management
81(1)
Prophylaxis
82(1)
Prosthetic Valves
82(1)
Adult Congenital Heart Disease
Introduction
83(1)
Patent Foramen Ovale
83(1)
Atrial Septal Defect
84(1)
Pathophysiology and Genetics
84(1)
Clinical Presentation
84(1)
Diagnostic Evaluation
84(1)
Treatment
85(1)
Reproductive Considerations
85(1)
Follow-up After Atrial Septal Defect Closure
85(1)
Ventricular Septal Defect
85(3)
Pathophysiology
85(2)
Clinical Presentation
87(1)
Diagnostic Evaluation
87(1)
Treatment
87(1)
Reproductive Considerations
87(1)
Follow-up After Ventricular Septal Defect Closure
87(1)
Patent Ductus Arteriosus
88(1)
Pathophysiology
88(1)
Clinical Presentation
88(1)
Diagnostic Evaluation
88(1)
Treatment
88(1)
Pulmonary Valve Stenosis
88(1)
Pathophysiology
88(1)
Clinical Presentation
88(1)
Diagnostic Evaluation
88(1)
Treatment
89(1)
Reproductive Considerations
89(1)
Aortic Coarctation
89(1)
Pathophysiology
89(1)
Clinical Presentation
89(1)
Diagnostic Evaluation
89(1)
Treatment
90(1)
Reproductive Considerations
90(1)
Follow-up After Aortic Coarctation Repair
90(1)
Tetralogy of Fallot
90(1)
Diagnostic Evaluation after Repair of Tetralogy of Fallot
91(1)
Treatment of Tetralogy of Fallot Residua
91(1)
Adults with Cyanotic Congenital Heart Disease
91(1)
General Management
91(1)
Eisenmenger Syndrome
92(1)
Diseases of the Aorta
Introduction
92(1)
Imaging of the Thoracic Aorta
92(1)
Thoracic Aortic Aneurysm
93(2)
Acute Aortic Syndromes
95(1)
Diagnosis and Evaluation
95(1)
Treatment
95(1)
Aortic Atheroma
96(1)
Abdominal Aortic Aneurysm
96(1)
Screening and Surveillance
96(1)
Treatment
97(1)
Peripheral Arterial Disease
Epidemiology and Screening
97(1)
Evaluation
98(1)
History and Physical Examination
98(1)
Diagnostic Testing
98(1)
Medical Therapy
99(1)
Cardiovascular Risk Reduction
99(1)
Symptom Relief
100(1)
Interventional Therapy
100(1)
Acute Limb Ischemia
101(1)
Cardiovascular Disease in Cancer Survivors
Cardiotoxicity of Radiation Therapy to the Thorax
102(1)
Manifestations and Monitoring of Cardiotoxicity After Completion of Radiation Therapy
102(1)
Management of Radiation-Induced Coronary Artery Disease
102(1)
Cardiotoxicity of Chemotherapy
103(2)
Manifestations and Monitoring of Cardiotoxicity After Completion of Chemotherapy
103(2)
Management of Chemotherapy-Induced Cardiotoxicity
105(1)
Pregnancy and Cardiovascular Disease
Cardiovascular Changes During Pregnancy
105(1)
Prepregnancy Evaluation
106(1)
Management of Cardiovascular Disease During Pregnancy
107
Peripartum Cardiomyopathy
107(1)
Medication Use During Pregnancy
107(1)
Anticoagulation Therapy During Pregnancy
108
Bibliography 111(6)
Self-Assessment Test 117(98)
Index 215
Disorders of the Esophagus
Symptoms of Esophageal Disorders
1(2)
Dysphagia
1(1)
Reflux
2(1)
Chest Pain
2(1)
Odynophagia
3(1)
Globus Sensation
3(1)
Nonmalignant Disorders of the Esophagus
3(7)
Esophageal Motility Disorders
3(3)
Infectious, Pill-Induced, and Eosinophilic Esophagitis
6(1)
Gastroesophageal Reflux Disease
7(3)
Metaplastic and Neoplastic Disorders of the Esophagus
10(2)
Barrett Esophagus
10(1)
Esophageal Carcinoma
11(1)
Disorders of the Stomach and Duodenum
Peptic Ulcer Disease
12(1)
Clinical Features, Diagnosis, and Complications
12(1)
Management
12(1)
Dyspepsia
13(1)
Clinical Manifestations
13(1)
Management
13(1)
Helicobacter pylori Infection
13(2)
Clinical Features
13(1)
Diagnostic Tests
14(1)
Treatment
15(1)
Eradication Testing
15(1)
Gastrointestinal Complications of NSAIDs
15(2)
Epidemiology and Risk Factors
15(1)
Prevention of NSAID-Induced Injury
16(1)
Gastroparesis
17(2)
Diagnosis
17(1)
Testing
18(1)
Management
18(1)
Gastric Polyps and Submucosal Lesions
19(1)
Gastric Polyps
19(1)
Gastric Subepithelial Masses
19(1)
Gastric Adenocarcinoma
20(1)
Epidemiology and Risk Factors
20(1)
Screening and Surveillance
20(1)
Clinical Manifestations and Diagnosis
20(1)
Complications of Gastric Surgical Procedures
20(3)
Bariatric Surgery Complications
20(2)
Other Gastric Resection Complications
22(1)
Disorders of the Pancreas
Acute Pancreatitis
23(2)
Clinical Presentation and Diagnosis
23(1)
Prognostic Criteria
24(1)
Management
24(1)
Complications
24(1)
Chronic Pancreatitis
25(1)
Clinical Presentation and Diagnosis
25(1)
Management
26(1)
Pancreatic Adenocarcinoma
26(1)
Clinical Presentation
27(1)
Diagnosis and Staging
27(1)
Autoimmune Pancreatitis and IgG4 Disease
27(1)
Clinical Presentation and Diagnosis
28(1)
Treatment
28(1)
Cystic Neoplasms of the Pancreas
28(1)
Pancreatic Neuroendocrine Tumors
29(1)
Disorders of the Small and Large Bowel
Diarrhea
30(1)
Characterization
30(1)
Evaluation and Management
30(1)
Malabsorption
31(3)
Types
31(1)
Malabsorption Syndromes
32(2)
Inflammatory Bowel Disease
34(5)
Risk Factors
34(1)
Clinical Manifestations
35(1)
Extraintestinal Manifestations
36(1)
Diagnosis
36(1)
Treatment
37(1)
Health Care Maintenance for the Patient with Inflammatory Bowel Disease
38(1)
Microscopic Colitis
38(1)
Constipation
39(2)
Irritable Bowel Syndrome
41(1)
Evaluation
41(1)
Management
42(1)
Diverticular Disease
42(1)
Ischemic Bowel Disease
43(2)
Acute Mesenteric Ischemia
43(1)
Chronic Mesenteric Ischemia
44(1)
Colonic Ischemia
44(1)
Colorectal Neoplasia
Epidemiology
45(1)
Pathophysiology
45(1)
Risk Factors
45(3)
Environmental Exposures
45(1)
Predisposing Conditions
46(1)
Nonsyndromic Family History
46(1)
Hereditary Colorectal Cancer Syndromes
46(2)
Screening
48(3)
Average Risk
48(3)
Increased Risk
51(1)
Surveillance
51(1)
Postpolypectomy
51(1)
Post-Colorectal Cancer Treatment
52(1)
Clinical Presentation
52(1)
Diagnosis and Staging
52(1)
Chemoprevention
52(1)
Disorders of the Liver
Approach to the Patient with Abnormal Liver Chemistry Studies
53(1)
Viral Hepatitis
54(3)
Hepatitis A
54(1)
Hepatitis B
54(1)
Hepatitis C
55(1)
Hepatitis D
56(1)
Hepatitis E
56(1)
Alcohol- and Drug-Induced Liver Disease
57(1)
Alcohol-Induced Liver Disease
57(1)
Drug- and Toxin-Induced liver Disease
57(1)
Autoimmune Hepatitis
58(1)
Metabolic Liver Disease
58(2)
Nonalcoholic Fatty Liver Disease
58(1)
Hereditary Hemochromatosis
59(1)
α1-Antitrypsin Deficiency
59(1)
Wilson Disease
59(1)
Cholestatic Liver Disease
60(1)
Primary Biliary Cirrhosis
60(1)
Primary Sclerosing Cholangitis
60(1)
Complications of Liver Disease
61(4)
Portal Hypertension and Gastroesophageal Varices
61(1)
Ascites
62(1)
Spontaneous Bacterial Peritonitis
63(1)
Hepatic Encephalopathy
63(1)
Hepatorenal Syndrome
64(1)
Hepatopulmonary Syndrome
64(1)
Portopulmonary Hypertension
64(1)
Hepatocellular Carcinoma
65(1)
Fulminant Hepatic Failure
65(1)
Liver Transplantation
66(1)
Hepatic Tumors, Cysts, and Abscesses
67(1)
Hepatic Cysts
67(1)
Focal Nodular Hyperplasia
67(1)
Hepatic Adenoma
67(1)
Hepatic Hemangioma
68(1)
Liver Abscesses
68(1)
Amebiasis
68(1)
Pregnancy-Related Liver Disease
68(1)
Health Care Maintenance of the Patient with Cirrhosis
69(1)
Metabolic Bone Disease
69(1)
Immunizations
69(1)
Medications to Avoid
70(1)
Nutrition
70(1)
Vascular Disorders of die liver
70(1)
Budd-Chiari Syndrome
70(1)
Portal Vein Thrombosis
71(1)
Disorders of the Gallbladder and Bile Ducts
Asymptomatic Gallstones
71(1)
Biliary Colic and Acute Cholecystitis
71(1)
Epidemiology and Clinical Manifestations
71(1)
Diagnosis
71(1)
Management
72(1)
Acalculous Cholecystitis
72(1)
Common Bile Duct Stones and Cholangitis
72(1)
Biliary Neoplasms
73(1)
Gallbladder Cancer
73(1)
Cholangiocarcinoma
73(1)
Ampullary Adenocarcinoma
73(1)
Biliary Cysts
73(1)
Gastrointestinal Bleeding
Overview
74(1)
Upper Gastrointestinal Bleeding
74(3)
Causes
74(1)
Evaluation
75(1)
Management
75(2)
Lower Gastrointestinal Bleeding
77(2)
Causes
77(1)
Evaluation
77(1)
Management
78(1)
Obscure Gastrointestinal Bleeding
79
Causes
79(1)
Evaluation
79(1)
Treatment
80
Bibliography 81(4)
Self-Assessment Test 85(70)
Index 155
Headache and Facial Pain
Approach to the Patient with Headache
1(1)
Secondary Headaches
1(4)
Common Features and Evaluation
1(2)
Thunderclap Headache
3(1)
Idiopathic Intracranial Hypertension (Pseudotumor Cerebri)
4(1)
Trigeminal Neuralgia (Tic Douloureux)
4(1)
Primary Headaches
5(5)
Migraine
5(4)
Tension-Type Headache
9(1)
Cluster Headache
10(1)
Related Primary Headache Syndromes
10(1)
Head Injury
Traumatic Brain Injury
10(1)
Concussive Head Injury
11(1)
Postconcussion Syndrome
11(1)
Epidural and Subdural Hematoma
12(1)
Head Injury in a Military Population
12(1)
Epilepsy
Features and Epidemiology of Epilepsy
12(1)
Initial Approach to die Patient with a First Seizure
13(1)
Clinical Presentations of Seizures
14(1)
Partial Seizures
14(1)
Generalized Seizures
14(1)
Epilepsy Syndromes
15(1)
Partial (Focal) Epilepsy
15(1)
Idiopathic Generalized Epilepsy
15(1)
Comorbidities and Complications of Epilepsy
16(1)
Mood Disorders
16(1)
Cognitive Problems
16(1)
Osteoporosis
16(1)
Sudden Unexplained Death in Epilepsy
16(1)
Diagnostic Evaluation of Seizures and Epilepsy
16(2)
Imaging Studies
16(1)
Electroencephalography
17(1)
Clinical Evaluation and Video Electroencephalographic Monitoring
17(1)
Treatment of Epilepsy
18(4)
Antiepileptic Drug Therapy
18(3)
Nonpharmacologic Therapy
21(1)
Status Epilepticus
22(2)
Generalized Convulsive Status Epilepticus
22(1)
Nonconvulsive Status Epilepticus
22(2)
Stroke
Epidemiology and Definition of Stroke
24(1)
Diagnosis of Stroke
24(1)
Stroke Subtypes
24(4)
Transient Ischemic Attack
24(2)
Ischemic Stroke
26(1)
Hemorrhagic Stroke
27(1)
Acute Ischemic Stroke
28(4)
Clinical Diagnosis
28(1)
Imaging Techniques
29(1)
Treatment
29(3)
Acute Hemorrhagic Stroke
32(1)
Intracerebral Hemorrhage
32(1)
Subarachnoid Hemorrhage
33(1)
Other Types of Stroke
33(3)
Dural Sinus Venous Thrombosis
33(3)
Carotid and Vertebral Artery Dissection
36(1)
Asymptomatic Aneurysm
36(1)
Admission to Stroke Units and Stroke Centers
36(1)
Secondary Stroke Prevention
36(2)
Hypertension
36(1)
Dyslipidemia
36(1)
Antithrombotic Treatment
37(1)
Surgery for Secondary Stroke
38(1)
Prevention of Stroke Complications
38(2)
Neurologic Worsening
38(1)
Medical Complications
39(1)
Perioperative Stroke
39(1)
Primary Prevention of Stroke
40(1)
Asymptomatic Carotid Stenosis
40(1)
Stroke Recovery and Long-Term Prognosis
40(1)
Dementia
General Overview
40(3)
Definition and Description
40(1)
Evaluation of the Patient with Suspected Dementia
41(1)
Differential Diagnosis of Dementia
42(1)
Diagnosis of Alzheimer Diseaseand Other Dementias
42(1)
Alzheimer Disease
43(2)
Prevalence
43(1)
Pathogenesis
43(1)
Clinical Features
43(1)
Pathologic Features
44(1)
Treatment
44(1)
Non-Alzheimer Dementias
45(2)
Dementia with Lewy Bodies
45(1)
Frontotemporal Dementia
46(1)
Vascular Dementia
46(1)
Normal Pressure Hydrocephalus
46(1)
Dementia and Driving
47(1)
Movement Disorders
Overview of Movement Disorders
47(1)
Parkinson Disease
47(4)
Clinical Features of Parkinson Disease
48(1)
Diagnosis of Parkinson Disease
49(1)
Treatment of Parkinson Disease
49(2)
Parkinson-Plus Syndromes
51(1)
Gait Disturbance
51(1)
Ataxia
52(1)
Essential Tremor
52(1)
Dystonia
53(1)
Chorea
53(1)
Tardive Dyskinesia
54(1)
Myoclonus
54(1)
Tic Disorders and Tourette Syndrome
55(1)
Wilson Disease
55(1)
Neuroleptic Malignant Syndrome
56(1)
Restless Legs Syndrome
56(1)
Multiple Sclerosis and Other Demyelinating Diseases
Spectrum, Pathophysiology, and Epidemiology
57(1)
Presenting Signs and Symptoms of Multiple Sclerosis
57(1)
Diagnosis of Multiple Sclerosis
58(1)
Diagnostic Criteria and Testing
58(1)
Differential Diagnosis of Multiple Sclerosis
59(1)
Clinical Course of Multiple Sclerosis
59(2)
Treatment of Multiple Sclerosis
61(3)
Lifestyle Modifications and General Health Care
61(1)
Treatment of Acute Exacerbations
61(1)
Disease-Modifying Therapies
62(1)
Symptomatic Management
63(1)
Disorders of the Spinal Cord
Presenting Symptoms and Signs of Myelopathies
64(1)
Compressive Myelopathies
65(1)
Clinical Presentation
65(1)
Diagnosis
65(1)
Treatment
65(1)
Noncompressive Myelopathies
66(2)
Clinical Presentation, Diagnosis, and Management
66(2)
Neuromuscular Disorders
Peripheral Neuropathies
68(5)
Overview
68(1)
Classification, Findings, and Diagnosis
68(2)
Mononeuropathies
70(1)
Polyneuropathies
70(3)
Treatment of Neuropathic Pain
73(1)
Amyotrophic Lateral Sclerosis
73(1)
Neuromuscular Junction Disorders
74(1)
Myasthenia Gravis
74(1)
Lambert-Eaton Myasthenic Syndrome
74(1)
Myopathies
75(2)
Overview
75(1)
Inflammatory Myopathy
76(1)
Endocrine-Related Myopathies
76(1)
Neuro-oncology
Intracranial Tumors
77(1)
Primary Central Nervous System Tumors
78(1)
Management of Intracranial Tumors
79(1)
Paraneoplastic Syndromes
79(1)
Brain Death
Description and Findings
80(1)
Apnea Test
81
Bibliography 81(4)
Self-Assessment Test 85(68)
Index 153
Hematopoietic Stem Cells and Their Disorders
Overview
1(1)
Bone Marrow Failure Syndromes
1(4)
Aplastic Anemia
1(2)
Pure Red Cell Aplasia
3(1)
Neutropenia
4(1)
Thrombocytopenia
4(1)
The Myelodysplastic Syndromes
5(1)
Myeloproliferative Disorders
6(7)
Polycythemia Vera
6(2)
Essential Thrombocythemia
8(1)
Chronic Myeloid Leukemia
8(1)
Primary Myelofibrosis
9(1)
Acute Myeloid Leukemia
10(1)
Acute Lymphoblastic Leukemia
11(1)
Hematopoietic Growth Factors
12(1)
Hematopoietic Stem Cell Transplantation
12(1)
Multiple Myeloma and Related Disorders
Overview
13(1)
Multiple Myeloma
13(3)
Clinical Manifestations and Findings
13(1)
Diagnosis and Prognosis
14(1)
Treatment
15(1)
Monoclonal Gammopathy of Undetermined Significance
15(1)
Immunoglobulin Light-Chain Amyloidosis
16(1)
Waldenstrom Macroglobulinemia
17(1)
Approach to Anemia
Introduction
18(2)
Anemia Due to Erythrocyte Underproduction or Maturation Defects
20(5)
Iron Deficiency
20(1)
Cobalamin (Vitamin B12) Deficiency
21(2)
Folate Deficiency
23(1)
Inflammatory Anemia
24(1)
Anemia of Kidney Disease
24(1)
Hemolytic Anemias
25(1)
Overview
25(1)
Congenital Hemolytic Anemias
26(6)
Hereditary Spherocytosis
26(1)
Glucose-6-Phosphate Dehydrogenase Deficiency
26(1)
Thalassemia
27(1)
Sickle Cell Syndromes
28(3)
Other Hemoglobinopathies
31(1)
Acquired Hemolytic Anemias
32(3)
Autoimmune Hemolytic Anemia
32(1)
Warm Autoimmune Hemolytic Anemia
32(1)
Cold Agglutinin Disease
32(1)
Drug-induced Autoimmune Hemolytic Anemia
33(1)
Microangiopathic Hemolytic Anemia
33(1)
Paroxysmal Nocturnal Hemoglobinuria
34(1)
Other Causes of Hemolysis
35(1)
Iron Overload Syndromes
35(1)
Hemochromatosis
35(1)
Secondary Iron Overload
36(1)
Transfusion
Cellular Products
36(3)
Erythrocytes
36(2)
Platelets
38(1)
Plasma Products
39(1)
Fresh Frozen Plasma
39(1)
Cryoprecipitate
39(1)
Other Plasma-derived Transfusion Products
39(1)
Transfusion Complications
39(2)
Hemolytic Reactions
39(1)
Nonhemolytic Reactions
40(1)
Allergic Reactions and Anaphylaxis
40(1)
Transfusion-associated Graft-Versus-Host Disease
40(1)
Infectious Complications
40(1)
Therapeutic Apheresis
41(1)
Bleeding Disorders
Overview of Normal Hemostasis
42(1)
Evaluation of Patients with Suspected Bleeding Disorders
42(1)
History and Physical Examination
42(1)
Laboratory Evaluation
43(1)
Congenital Bleeding Disorders
43(3)
Hemophilia A and B
43(2)
von Willebrand Disease
45(1)
Acquired Bleeding Disorders
46(1)
Acquired Hemophilia
46(1)
Coagulopathy of Liver Disease
46(1)
Disseminated Intravascular Coagulation
46(1)
Vitamin K Deficiency
46(1)
Platelets
Normal Platelet Physiology
47(1)
Approach to die Patient with Thrombocytopenia
47(2)
Immune (Idiopathic) Thrombocytopenic Purpura
49(1)
Heparin-induced Thrombocytopenia
50(1)
Thrombotic Thrombocytopenic Purpura-Hemolytic Uremic Syndrome
51(1)
Other Thrombocytopenias Due to Underproduction
52(1)
Qualitative Platelet Disorders
52(1)
Platelet Function Testing
52(1)
Acquired Platelet Dysfunction
52(1)
Thrombotic Disorders
Pathophysiology of Thrombosis and Thrombophilia
53(1)
Inherited Thrombophilic Conditions
53(1)
Factor V Leiden
53(1)
Prothrombin G20210A Gene Mutation
53(1)
Antithrombin Deficiency
53(1)
Protein C Deficiency
53(1)
Protein S Deficiency
53(1)
Dysfibrinogenemia
54(1)
Acquired Thrombophilic Conditions
54(1)
Surgery
54(1)
Trauma
54(1)
Cancer
54(1)
Antiphospholipid Syndrome
54(1)
Catastrophic Antiphospholipid Syndrome
55(1)
Other Acquired Thrombophilic Disorders
55(1)
Management and Prevention
55(7)
Thrombophilia Testing
55(1)
Diagnosis
56(1)
Use of Anticoagulants
56(3)
Prevention
59(2)
Treatment
61(1)
Hematologic Issues in Pregnancy
Gestational Anemia
62(1)
Iron Deficiency
62(1)
Folate Deficiency
62(1)
Sickle Cell Disease
63(1)
Thrombocytopenia in Pregnancy
63(2)
Gestational Thrombocytopenia
63(1)
Immune Thrombocytopenic Purpura
63(1)
Microangiopathy of Pregnancy
64(1)
Thrombophilia and Venous Thromboembolism in Pregnancy
65(1)
Epidemiology, Pathophysiology, and Risk Factors
65(1)
Diagnosis
66(1)
Management
66(1)
Issues in Oncology
Staging
66(1)
Treatment
67(2)
Surgical Resection
67(1)
Adjuvant Therapy
67(1)
Defining Treatment Goals
67(1)
Era of Personalized Cancer Treatment
68(1)
Breast Cancer
Introduction
69(1)
Epidemiology and Risk Factors
69(1)
Chemoprevention and Other Risk Reduction Strategies
70(1)
Primary Breast Cancer Therapy
71(1)
Ductal Carcinoma in Situ
71(1)
Invasive Breast Cancer
71(1)
Adjuvant Systemic Therapy for Early-Stage Breast Cancer
72(1)
Adjuvant Endocrine Therapy
72(1)
Adjuvant Chemotherapy
73(1)
Locally Advanced and Inflammatory Breast Cancer Therapy
73(1)
Breast Cancer Follow-up and Survivorship
74(1)
Metastatic Breast Cancer
74(1)
Ovarian and Cervical Cancer
Ovarian Cancer
75(3)
Epidemiology and Risk Factors
75(1)
Screening and Risk Reduction Strategies
75(1)
Diagnosis
76(1)
Treatment
76(1)
Management of Recurrent Ovarian Cancer
77(1)
Monitoring and Follow-Up
77(1)
Supportive Care
77(1)
Cervical Cancer
78(1)
Epidemiology and Risk Factors
78(1)
Diagnosis and Staging
78(1)
Treatment
78(1)
Prognosis
78(1)
Surveillance
79(1)
Gastrointestinal Malignancies
Colorectal Cancer
79(2)
Staging
79(1)
Treatment
80(1)
Postoperative Colorectal Cancer Surveillance
81(1)
Anal Cancer
81(1)
Pancreatic Cancer
81(1)
Esophageal Cancer
82(1)
Gastric Cancer
83(1)
Gastrointestinal Neuroendocrine Tumors
83(1)
Lung Cancer
Epidemiology
84(1)
Screening
84(1)
Diagnosis
84(1)
Non-Small Cell Lung Cancer
85(2)
Staging
85(1)
Treatment
86(1)
Small Cell Lung Cancer
87(1)
Diagnosis and Staging
87(1)
Treatment
87(1)
Head and Neck Cancer
Risk Factors
88(1)
Diagnosis and Staging
88(1)
Treatment
89(1)
Genitourinary Cancer
Prostate Cancer
89(4)
Epidemiology and Risk Factors
89(1)
Diagnosis and Staging
90(1)
Treatment
90(2)
Prostate Cancer Follow-up and Posttreatment Recurrence
92(1)
Testicular Cancer
93(1)
Diagnosis and Staging
93(1)
Treatment
93(1)
Bladder Cancer
94(1)
Diagnosis and Staging
94(1)
Treatment
95(1)
Renal Cell Cancer
95(2)
Diagnosis and Staging
96(1)
Treatment
96(1)
Lymphadenopathy and Lymphoid Malignancies
Epidemiology and Risk Factors of Malignant Lymphomas
97(1)
Diagnosis of Malignant Lymphomas
98(1)
Classification, Staging, and Prognosis of Malignant Lymphoma
98(2)
Overview and Treatment of Indolent Lymphomas
100(2)
Follicular Lymphoma
100(1)
Mucosa-associated Lymphoid Tissue (MALT) Lymphoma
101(1)
Chronic Lymphocytic Leukemia
101(1)
Hairy Cell Leukemia
102(1)
Overview and Treatment of Aggressive Lymphomas
102(2)
Diffuse Large Cell Lymphoma
102(1)
Mantle Cell Lymphoma
103(1)
Hodgkin Lymphoma
103(1)
Cutaneous T-cell Non-Hodgkin Lymphoma
104(1)
Cancer of Unknown Primary Site
Introduction
104(1)
Diagnosis
104(1)
Favorable Prognostic Subgroups
105(1)
Poorly Differentiated Carcinoma
105(1)
Isolated Regional Lymphadenopathy
105(1)
Peritoneal Carcinomatosis in Women
105(1)
Management of Patients Not in Favorable Prognosis Subgroups
106(1)
Melanoma
Introduction
106(1)
Risk Factors and Prognosis
106(1)
Treatment
106(1)
Primary Central Nervous System Tumors
107(1)
Oncologic Urgencies and Emergencies
Structural Urgencies and Emergencies
107(2)
Superior Vena Cava Syndrome
107(1)
Brain Metastases Causing Increased Intracranial Pressure
108(1)
Spinal Cord Compression
108(1)
Malignant Pleural and Pericardial Effusions
108(1)
Metabolic Urgencies and Emergencies
109(1)
Tumor Lysis Syndrome
109(1)
Hypercalcemia
109(1)
Effects of Cancer and Cancer Therapy
109(2)
Hematopoietic Disorders
109(1)
Disorders of Cardiac Function
110(1)
Disorders of Pulmonary Function
110(1)
Disorders of Genitourinary and Renal Function
110(1)
Sexual Function
110(1)
Secondary Malignancies
110(1)
Other Issues
111(1)
Bibliography 111(6)
Self-Assessment Test 117(104)
Index 221