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Modeling of Microscale Transport in Biological Processes [Hardback]

Edited by (Associate Professor, Department of Mechanical Engineering, University of Canterbury, Christchurch, New Zealand)
  • Formāts: Hardback, 394 pages, height x width: 235x191 mm, weight: 1000 g
  • Izdošanas datums: 16-Jan-2017
  • Izdevniecība: Academic Press Inc
  • ISBN-10: 0128045957
  • ISBN-13: 9780128045954
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Modeling of Microscale Transport in Biological ProcessesPalielināt
  • Formāts: Hardback, 394 pages, height x width: 235x191 mm, weight: 1000 g
  • Izdošanas datums: 16-Jan-2017
  • Izdevniecība: Academic Press Inc
  • ISBN-10: 0128045957
  • ISBN-13: 9780128045954
Citas grāmatas par šo tēmu:
Permanent link: https://www.kriso.lv/db/9780128045954.html
Keywords:

Modelling of Microscale Transport in Biological Processes provides a compendium of recent advances in theoretical and computational modeling of biotransport phenomena at the microscale. The simulation strategies presented range from molecular to continuum models and consider both numerical and exact solution method approaches to coupled systems of equations.

The biological processes covered in this book include digestion, molecular transport, microbial swimming, cilia mediated flow, microscale heat transfer, micro-vascular flow, vesicle dynamics, transport through bio-films and bio-membranes, and microscale growth dynamics.

The book is written for an advanced academic research audience in the fields of engineering (encompassing biomedical, chemical, biological, mechanical, and electrical), biology and mathematics. Although written for, and by, expert researchers, each chapter provides a strong introductory section to ensure accessibility to readers at all levels.

  • Features recent developments in theoretical and computational modeling for clinical researchers and engineers
  • Furthers researcher understanding of fluid flow in biological media and focuses on biofluidics at the microscale
  • Includes chapters expertly authored by internationally recognized authorities in the fundamental and applied fields that are associated with microscale transport in living media

Papildus informācija

Featuring recent developments in theoretical and computational, this innovative work furthers researcher understanding of fluid flow in biological media and focuses on biofluidics at the microscale
Contributors ix
Preface xi
1 Molecular Simulations of Complex Membrane Models
D. Jefferies
S. Khalid
1.1 Introduction
1(2)
1.2 Unsaturated Carbon Chains
3(1)
1.3 Membrane Proteins
4(2)
1.4 Sterols
6(1)
1.5 Eukaryotic Membranes
6(2)
1.6 Prokaryotic Membranes
8(2)
1.7 Viral Membranes
10(1)
1.8 Membrane Fusion
11(1)
1.9 Graphitic Nanomaterials
12(1)
1.10 Nanoparticles
13(1)
1.11 On-Going Work
13(1)
1.12 Outlook and Conclusion
14(5)
2 Microbial Strategies for Oil Biodegradation
G.E. Kapellos
2.1 Introduction
19(2)
2.2 Overview of the Biodegradation Process
21(4)
2.3 Microbial Growth Modes on Oily Substrates
25(8)
2.4 Microscale Modeling Considerations
33(1)
2.5 Summary and Outlook
34(7)
3 Modeling and Measurement of Biomolecular Transport and Sensing in Microfluidic Cell Culture and Analysis Systems
J.F. Wong
C.A. Simmons
E.W.K. Young
3.1 Introduction
41(1)
3.2 Basic Principles of Microscale Cell Culture
42(2)
3.3 Theory and Equations: Fluid Flow, Mass Transport, and Biochemical Reactions
44(8)
3.4 Review of Microfluidic Transport Models
52(16)
3.5 Review of Theoretical Model Experimental Validation
68(3)
3.6 Summary and Conclusions
71(6)
4 Coupling Microscale Transport and Tissue Mechanics: Modeling Strategies for Arterial Multiphysics
M. Marino
G. Pontrelli
G. Vairo
P. Wriggers
4.1 Introduction
77(2)
4.2 Brief on Arterial Tissues
79(5)
4.3 Arterial Multiphysics Modeling
84(10)
4.4 An Axisymmetric Case Study
94(11)
4.5 Conclusions
105(8)
Appendix A Along-the-Chord Collagen Fiber Tangent Modulus
106(2)
Appendix B Microstructure of Aortic Media Layer
108(5)
5 Modeling Cystic Fibrosis and Mucociliary Clearance
R. Chatelin
D. Anne-Archard
M. Murris-Espin
D. Sanchez
M. Thiriet
A. Didier
P. Poncet
5.1 Mucociliary Clearance and Cystic Fibrosis
113(7)
5.2 Newtonian Models
120(17)
5.3 Rheology of Mucus and Non-Newtonian Models
137(12)
5.4 Concluding Remarks
149(6)
6 Intracellular Microfluid Transportation in Fast Growing Pollen Tubes
S. Liu
H. Liu
M. Lin
F. Xu
T.J. Lu
6.1 Introduction
155(2)
6.2 Modeling Fluid Flow of Fountain Streaming in Pollen Tubes
157(3)
6.3 Modeling Intracellular Microfluid Transportation in Pollen Tubes
160(1)
6.4 Results and Discussion
161(7)
6.5 Conclusions
168(3)
7 Microorganisms and Their Response to Stimuli
R.J. Clarke
7.1 Introduction
171(2)
7.2 Swimming Dynamics
173(2)
7.3 Response to Stimuli
175(6)
7.4 Non-Flowing Suspensions
181(9)
7.5 Flowing Suspensions
190(12)
7.6 Conclusions
202(5)
8 Nano-Swimmers in Lipid-Bilayer Membranes
M.-J. Huang
A. Mikhailov
8.1 Introduction
207(1)
8.2 Methods
208(6)
8.3 Results
214(3)
8.4 Conclusions
217(4)
9 Phase Field Modeling of Inhomogeneous Biomembranes in Flow
S. Aland
9.1 Motivation
221(1)
9.2 Energy of the System
222(2)
9.3 Hydrodynamic Models
224(3)
9.4 Inhomogeneous Membranes
227(4)
9.5 Numerical Methods
231(1)
9.6 The Phase Field Method
232(3)
9.7 Phase Field Models for Inhomogeneous Membranes
235(8)
10 Modeling and Experimental Analysis of Thermal Therapy during Short Pulse Laser Irradiation
S. Miller
C. Gross Jones
K. Mitra
10.1 Introduction
243(5)
10.2 Methods
248(5)
10.3 Results and Discussion
253(4)
10.4 Conclusions
257(4)
11 Micro-Scale Bio-Heat Diffusion Using Green's Functions
F. De Monte
A. Haji-Sheikh
11.1 Introduction
261(1)
11.2 Balance Equations
262(8)
11.3 Dual-Phase Lag Bio-Heat Diffusion Equation
270(7)
11.4 Boundary and Initial Conditions
277(6)
11.5 Temperature Solution with Homogeneous Boundary Conditions
283(4)
11.6 Temperature Solution with Non-Homogeneous Boundary Conditions
287(2)
11.7 Green's Functions for Finite Regular Tissues
289(4)
11.8 Temperature Distribution in a Laser-Irradiated Biological Tissue
293(9)
11.9 Conclusions
302(9)
Appendix A
305(1)
Appendix B
306(5)
12 Microstructural Influences on Growth and Transport in Biological Tissue--- A Multiscale Description
L. Irons
J. Collis
R.D. O'Dea
12.1 Introduction
311(2)
12.2 Formulation: Nutrient-Limited Microscale Growth of a Porous Medium
313(5)
12.3 Multiple Scales Analysis
318(4)
12.4 Results
322(10)
12.5 Discussion
332(3)
13 How Dense Core Vesicles Are Delivered to Axon Terminals -- A Review of Modeling Approaches
I.A. Kuznetsov
A.V. Kuznetsov
13.1 Introduction
335(1)
13.2 Review of Relevant Literature
336(3)
13.3 Mathematical Models of DCV Transport and Accumulation in Axon Terminals
339(5)
13.4 Results and Discussion
344(5)
13.5 Future Work
349(1)
13.6 Conclusions
349(4)
14 Modeling of Food Digestion
S. Marze
14.1 Introduction
353(1)
14.2 The Complexity of Food Digestion and Absorption
353(3)
14.3 Development of Digestion and Absorption Modeling
356(3)
14.4 Microscale Modeling of Food Digestion and Absorption
359(10)
14.5 Conclusion
369(6)
Index 375
Sid Becker is an Associate Professor in the Department of Mechanical Engineering at the University of Canterbury. He is an Alexander von Humboldt Fellow and is a recipient of the Royal Society of New Zealand Marsden Grant. He has held academic positions in Germany, the United States, and New Zealand. His research is primarily in computational and analytical modelling of heat and mass transfer processes in biological media. Dr. Becker is also the editor of the book Modeling of Microscale Transport in Biological Processes (2017) and co-editor of the books Heat Transfer and Fluid Flow in Biological Processes (2015), and Transport in Biological Media (2013).