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Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Methods and Protocols [Hardback]

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  • Formāts: Hardback, 296 pages, height x width: 254x178 mm, 33 Illustrations, color; 5 Illustrations, black and white; XI, 296 p. 38 illus., 33 illus. in color. With online files/update., 1 Hardback
  • Sērija : Methods in Molecular Biology 2920
  • Izdošanas datums: 16-May-2025
  • Izdevniecība: Springer-Verlag New York Inc.
  • ISBN-10: 1071644971
  • ISBN-13: 9781071644973
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  • Formāts: Hardback, 296 pages, height x width: 254x178 mm, 33 Illustrations, color; 5 Illustrations, black and white; XI, 296 p. 38 illus., 33 illus. in color. With online files/update., 1 Hardback
  • Sērija : Methods in Molecular Biology 2920
  • Izdošanas datums: 16-May-2025
  • Izdevniecība: Springer-Verlag New York Inc.
  • ISBN-10: 1071644971
  • ISBN-13: 9781071644973
Citas grāmatas par šo tēmu:

This detailed volume explores the condition of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and the recent techniques used to investigate the dysfunctional pathophysiology in patients. Beginning with a section on diagnosis, the book continues by covering the chronic cellular and  molecular changes in the peripheral immune system that affect their molecular homeostasis, metabolic changes, as well as imaging technologies to understand the brain’s dysfunction in aberrantly regulating body physiology in ME/CFS. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

 

Authoritative and practical, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Methods and Protocols serves as an ideal guide for clinicians and researchers working to better understand post-viral/stressor conditions in order to improve the lives of those affected with ME/CFS and, most recently, long COVID.

How a Clinician Makes a Diagnosis for Myalgic Encephalomyelitis/Chronic
Fatigue Syndrome (ME/CFS).- Using the Ratio of Phosphorylated to
Non-Phosphorylated Forms of Stress Kinase PKR as a Potential Diagnostic Test
for ME/CFS.- Using Single-Cell Raman Microspectroscopy to Profile Human
Peripheral Blood Mononuclear Cells.- MicroRNA Profiling of Blood
Extracellular Vesicles in ME/CFS.- Deep Immunophenotyping in ME/CFS Using
Spectral Cytometry.- Analysis of Transient Receptor Potential Ion Channels in
ME/CFS.- Stress-Induced Changes in Immune Signatures in ME/CFS Patients
Determined by Transcriptome Analysis.- Quantitative Proteomics on Immune
Cells of ME/CFS Patients Using SWATH-MS.- Application of DNA Methylome
Analysis to Patients with ME/CFS.- Repeated Cardiopulmonary Exercise Testing
of ME/CFS Patients.- Real-Time Measurement of Mitochondrial Function and
Glycolysis in Lymphoblastoid Cell Lines.- Mitochondrial Measures in Primary
Cells Isolated from Patients with ME/CFS.- Measuring Biomarkers of Oxidative
Stress in ME/CFS Patients.- Measurement of Genetic Variations in ME/CFS
Patients in the IDO2 Gene Encoding an Enzyme Metabolizing Tryptophan.- Review
of Neuroimaging Methods in ME/CFS.- Profiling Antibody Reactivity to Gut
Microbes in ME/CFS Patients.