| Contributors |
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xiii | |
| Preface |
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xxvii | |
| Acknowledgments |
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xxxi | |
| About the Editor |
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xxxiii | |
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I INTRODUCTION AND HISTORY |
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1 Paul Ehrlich and the Early History of Granulocytes |
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3 | (14) |
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2 The Phagocyte, Metchnikoff, and the Foundation of Immunology |
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17 | (14) |
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3 Growth and Differentiation Factors |
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31 | (14) |
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4 Evolution of Myeloid Cells |
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45 | (14) |
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5 Advances in Myeloid-Like Cell Origins and Functions in the Model Organism Drosophila melanogaster |
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59 | (20) |
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6 Monocyte, Macrophage, and Dendritic Cell Development: the Human Perspective |
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79 | (20) |
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7 Myeloid Cell Turnover and Clearance |
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99 | (20) |
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8 Transcriptional Regulation and Macrophage Differentiation |
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119 | (22) |
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9 Murine Monocytes: Origins, Subsets, Fates, and Functions |
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141 | (14) |
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10 Dendritic Cells in the Immune System: History, Lineages, Tissues, Tolerance, and Immunity |
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155 | (54) |
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11 Antigen Processing and Presentation Mechanisms in Myeloid Cells |
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209 | (16) |
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225 | (10) |
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13 Osteoclasts---Key Players in Skeletal Health and Disease |
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235 | (22) |
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14 The Regulatory Function of Eosinophils |
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257 | (16) |
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IV RECRUITMENT, INFLAMMATION, AND REPAIR |
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15 Intravital Imaging of Myeloid Cells: Inflammatory Migration and Resident Patrolling |
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273 | (22) |
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16 Multifaceted Functions of NOD-Like Receptor Proteins in Myeloid Cells at the Intersection of Innate and Adaptive Immunity |
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295 | (10) |
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17 Inflammasomes in Myeloid Cells: Warriors Within |
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305 | (20) |
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18 Inflammation---a Critical Appreciation of the Role of Myeloid Cells |
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325 | (18) |
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19 Lipid Mediators in Inflammation |
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343 | (24) |
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20 Macrophage Proresolving Mediators---the When and Where |
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367 | (18) |
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21 Myeloid Cells in Cutaneous Wound Repair |
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385 | (22) |
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V RECOGNITION, SIGNALING, AND GENE EXPRESSION |
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22 The Role and Function of Fey Receptors on Myeloid Cells |
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407 | (22) |
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23 Complement Receptors in Myeloid Cell Adhesion and Phagocytosis |
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429 | (18) |
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24 Toll-Like Receptor Signaling and Its Inducible Proteins |
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447 | (8) |
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25 Lectin Receptors Expressed on Myeloid Cells |
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455 | (30) |
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26 G Protein-Coupled Receptors in Macrophages |
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485 | (22) |
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27 Molecular Mechanisms of Phagosome Formation |
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507 | (20) |
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28 Role of the Cytoskeleton in Myeloid Cell Function |
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527 | (16) |
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29 Coordinated Regulation of Signaling Pathways during Macrophage Activation |
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543 | (10) |
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30 Genome-Wide Approaches to Defining Macrophage Identity and Function |
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553 | (18) |
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31 Epigenetic Regulation of Myeloid Cells |
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571 | (22) |
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32 Secretion from Myeloid Cells: Secretory Lysosomes |
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593 | (6) |
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33 The NADPH Oxidase and Microbial Killing by Neutrophils, With a Particular Emphasis on the Proposed Antimicrobial Role of Myeloperoxidase within the Phagocytic Vacuole |
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599 | (16) |
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34 Evolution of Cell-Autonomous Effector Mechanisms in Macrophages versus Non-Immune Cells |
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615 | (22) |
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637 | (12) |
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36 Metalloproteinases: a Functional Pathway for Myeloid Cells |
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649 | (12) |
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VII IMMUNOREGULATION AND INFECTION |
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37 Interplay between Myeloid Cells and Humoral Innate Immunity |
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661 | (18) |
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38 Adaptive Characteristics of Innate Immune Responses in Macrophages |
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679 | (8) |
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39 Intestinal Mononuclear Phagocytes in Health and Disease |
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687 | (14) |
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40 Strategies Used by Bacteria to Grow in Macrophages |
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701 | (26) |
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41 Mechanisms of Defense against Intracellular Pathogens Mediated by Human Macrophages |
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727 | (12) |
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42 Myeloid Cells in Asthma |
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739 | (20) |
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43 Myeloid Cell Phenotypes in Susceptibility and Resistance to Helminth Parasite Infections |
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759 | (12) |
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44 Induction of Immunological Tolerance as a Therapeutic Procedure |
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771 | (18) |
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VIII METABOLIC AND MALIGNANT DISEASE |
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45 Glutathione and Glutathione Transferase Omega 1 as Key Posttranslational Regulators in Macrophages |
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789 | (14) |
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46 Macrophages and Iron Metabolism |
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803 | (10) |
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47 Mechanisms of Myeloid Cell Modulation of Atherosclerosis |
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813 | (12) |
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48 Macrophages in Endocrine Glands, with Emphasis on Pancreatic Islets |
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825 | (8) |
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49 Tumor-Induced Myeloid-Derived Suppressor Cells |
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833 | (24) |
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50 Myeloid Cell Origins, Differentiation, and Clinical Implications |
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857 | (20) |
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| Index |
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877 | |
Biežāk uzdotie jautājumi par e-grāmatām