At the frontier of modern medicine lies a revolution in drug delivery systems that operates at the scale of billionths of a meter. Nano Carriers for Nucleic Acids and Proteins presents a comprehensive exploration of these groundbreaking technologies that are reshaping therapeutic approaches across medical science.
From fundamental concepts to cutting-edge applications, this comprehensive volume brings together world-class researchers to provide an in-depth examination of:
- Design principles and characteristics of various nanocarrier systems
- Advanced delivery mechanisms for nucleic acids and proteins
- Breakthrough applications in gene therapy and cancer immunotherapy
- Critical aspects of translating laboratory success to clinical implementation
Featuring detailed coverage of lipid-based, polymer-based, inorganic, and bio-inspired nanocarriers, this essential resource bridges the gap between theoretical understanding and practical application. Whether you're developing new therapeutic approaches, optimizing delivery systems, or exploring the frontiers of nanomedicine, this comprehensive guide provides the insights and frameworks needed to advance your work.
At the frontier of modern medicine lies a revolution in drug delivery systems that operates at the scale of billionths of a meter. "Nano Carriers for Nucleic Acids and Proteins" presents a comprehensive exploration of these groundbreaking technologies that are reshaping therapeutic approaches across medical science.
Chapter 1: Introduction to Nanocarriers for Nucleic Acids and Proteins.
Juan C. Cruz, Yashwant V Pathak and Luis H. Reyes
Chapter 2: Design Principles of Nanocarriers: Size, Shape, and
Surface Properties, Stimuli-Responsive Systems.
Juan C. Cruz, Luis H. Reyes
Chapter 3: Lipid-Based Nano Carriers for Nucleic Acids and Proteins:
Liposomes, solid lipid nanoparticles, nanostructured lipid carriers
Biswajit Basu, Ayon Dutta, Dipanjana Ash, Bhupendra Prajapati*, Swarupananda
Mukherjee
Chapter 4: Polymer-based nanocarriers: dendrimers, polymeric micelles,
hydrogels
Juan C. Cruz and Luis H. Reyes
Chapter 5: Inorganic nano carriers: gold nanoparticles, iron nanoparticles,
silica nanoparticles, quantum dots
Juan C. Cruz,and Luis H. Reyes
Chapter 6: Carbon-based nano carriers: Carbon nanotubes, graphene oxide,
fullerenes, and Carbon dots
Cristian F. Rodrķguez, Paula Guzmįn-Sastoque, Coryna Rodriguez-Bazurto, Juan
C. Rojas-Hernįndez, Luis H. Reyes, Juan C. Cruz
Chapter 7 : Virus Inspired Nano Carriers
Ankita Alice Singh, Seema Kohli
Chapter 8: Nucleic acid nano carriers DNA nanostructures, RNA nanostructures,
hybrid nucleic acid systems
Komal Parmar, and Jayvadan Patel
Chapter 9 : Protein-based nano carriers: protein cages, self-assembling
peptides, fusion proteins,
Nishant B. Chopade, Prashant K. Deshmukh,and Mahesh P. More
Chapter 10 : Nanocarrier Functionalization Strategies: Targeting Ligands,
Imaging Agents, stimuli-responsive Elements
Sampada Satish Shinde, Bhavna Sonule, Lalit Kumar
Chapter 11: Delivery of nucleic acids using nano carriers:
siRNA and miRNA delivery, mRNA and DNA delivery, CRISPR-Cas systems
Paula GuzmįnSastoque,Marķa Camila Monsalve, Cristian F. Rodrķguez, Stiven
Castellanos,Juan C. Cruz, and Luis H. Reyes
Chapter 12: Delivery of proteins using nanocarriers: enzymes, antibodies and
growth factors
Jennifer Suurbaar,
Frederick Sarfo-Antwi Seth Kwabena Amponsah,
Chapter 13 : Nanocarrier in gene therapy
Sinjini Sarkar, Swarupananda Mukherjee, Shilpa Chatterjee, Biswajit Basu,
Dipanjan Karati, Bhupendra Prajapati
Chapter 14: Nanocarriers in Cancer Immunotherapy: Personalized Cancer
Vaccines, Immune Checkpoint Modulation,
Adoptive T-Cell Therapy
Vineet Mahajan and Yashwant Pathak
Chapter 15: Future perspectives and challenges: clinical translation and
regulatory aspects, scale-up and
manufacturing, ethical considerations
Aparoop Das, Kalyani Pathak Riya Saikia, Manash Pratim Pathak,Urvashee Gogoi,
Dibyajyoti Das, Jon Jyoti Sahariah, Saptasikha Gogoi and Sukanya Sonowa
Chapter 16: Regulatory Toxicology of Biologics: Safeguarding Health in
Biotherapeutic Development
Satish Rojekar, Nishant Talati, Shahin Vhora,
Nidhi Kotadiya, Mitul Talala, Ruby Chrisitan, Vikas Jain, Tosha Pandya, Disha
Suthar, and Kinjal Parikh
Luis H. Reyes, PhD, is an associate professor at Universidad de Los Andes (Bogotį, Colombia), where he leads research at the intersection of biological engineering and therapeutic delivery systems. He holds a BS in Chemical Engineering from Universidad Industrial de Santander (Colombia) and a PhD in Chemical Engineering from Texas A&M University.
Juan C. Cruz, PhD, is a distinguished researcher and engineer at the Department of Biomedical Engineering, Universidad de Los Andes (Bogotį, Colombia), where he has been advancing the frontiers of nanobiotechnology since 2016. He holds a BS in Chemical Engineering from the National University of Colombia and earned his PhD in Chemical Engineering from Kansas State University, where his innovative work established a new platform for enzyme immobilization for applicstions in non-aqueous media.
Yashwant V. Pathak received his PhD from Nagpur University, India, Executive MBA and Masters in Conflict Management, Sullivan University, Louisville, KY, USA. He has over 45 years experience in Academia and Industry. Presently, he is Professor and Associate Dean for Faculty Affairs at Taneja College of Pharmacy, University of South Florida, Tampa, FL, USA. Yashwant has published over 400 research papers, reviews and chapters with close to 5000 citations in Google Scholar. He edited over 70 books in nanotechnology, nutraceuticals, drug delivery systems, artificial intelligence, and artificial neural network. He has keen interest in conflict management and edited several books in the areas of organizational conflict management, handbook of organizational conflict management, Eastern and Indigenous perspectives in conflict management, RSS way of resolving conflicts and these two volumes on nonprofit organizations conflict management.
