Contributors |
|
ix | |
Editors Biography |
|
xiii | |
Preface |
|
xv | |
|
Chapter 1 Current state of nanostructured biomaterials for oral and cranio-maxillofacial rehabilitation |
|
|
1 | (12) |
|
|
1 | (2) |
|
1.2 Nanoscale Texturized Surfaces of Implants |
|
|
3 | (1) |
|
1.3 Nanostructured Bioactive Ceramics and Composites |
|
|
4 | (3) |
|
1.4 Functionally Graded Nanostructured Biomaterials |
|
|
7 | (1) |
|
|
8 | (5) |
|
|
9 | (4) |
|
Chapter 2 Nanostructured surfaces of cranio-maxillofacial and dental implants |
|
|
13 | (28) |
|
|
13 | (1) |
|
2.2 Dental and Cranio-Maxillofacial Implants |
|
|
14 | (1) |
|
|
15 | (1) |
|
2.4 Physical and Chemical Methods for Modification of Implant Surfaces |
|
|
16 | (15) |
|
2.4.1 Modification of Surfaces by Grit-Blasting and Etching |
|
|
21 | (2) |
|
2.4.2 Functionalization of Titanium Surfaces by Anodization |
|
|
23 | (5) |
|
2.4.3 Functionalization by Using Bioactive Ceramics |
|
|
28 | (2) |
|
2.4.4 Surfaces Coated by Synthetic and Natural Absorbable Polymers |
|
|
30 | (1) |
|
|
31 | (10) |
|
|
32 | (9) |
|
Chapter 3 Degradation of titanium-based implants |
|
|
41 | (22) |
|
|
41 | (2) |
|
3.2 The Corrosive Oral Environment |
|
|
43 | (2) |
|
3.3 Corrosion of Titanium |
|
|
45 | (2) |
|
3.4 Simultaneous Degradation of Titanium by Corrosion and Wear Interactions |
|
|
47 | (4) |
|
3.5 Interaction Between Wear Debris and Surrounding Tissues |
|
|
51 | (3) |
|
|
54 | (9) |
|
|
55 | (8) |
|
Chapter 4 Adverse local and systemic effect of nanoparticles released from oral and cranio-maxillofacial implants |
|
|
63 | (18) |
|
|
63 | (1) |
|
4.2 Degradation Products Released From Implant and Prosthetic Structures |
|
|
64 | (2) |
|
4.3 Local Toxicity Surrounding Prosthetic and Implant Structures |
|
|
66 | (4) |
|
4.4 Evidence of Systemic Toxicity Caused by Degradation Products |
|
|
70 | (2) |
|
4.5 Current Limitations on the Cytoxicity of Wear Particles |
|
|
72 | (1) |
|
|
73 | (8) |
|
|
73 | (8) |
|
Chapter 5 Nanostructured polymer matrix composites for oral and cranio-maxillofacial rehabilitation |
|
|
81 | (16) |
|
|
81 | (1) |
|
5.2 History of Polymeric Materials in Dentistry |
|
|
82 | (2) |
|
5.3 Inorganic Fillers for Resin Composites |
|
|
84 | (4) |
|
5.4 Thermoset Polymer Matrix Composites |
|
|
88 | (1) |
|
5.5 Thermoplastic Matrix Composites |
|
|
89 | (5) |
|
5.6 Currents Status and Future Challenges |
|
|
94 | (3) |
|
|
95 | (1) |
|
|
96 | (1) |
|
Chapter 6 Nanostructured biocompatible ceramics and glass-ceramics |
|
|
97 | (22) |
|
|
97 | (1) |
|
6.2 Bioacompatible Ceramics and Glass-Ceramics |
|
|
97 | (11) |
|
6.2.1 First Generation: Bioinert Ceramics |
|
|
98 | (1) |
|
6.2.2 Second Generation: Bioactive Ceramics |
|
|
99 | (8) |
|
6.2.3 Third Generation: Tissue Self-Regeneration Inducers |
|
|
107 | (1) |
|
6.3 Nano-Pores and Hierarchical Porosity |
|
|
108 | (4) |
|
6.3.1 Macro, Meso, and Microporosity |
|
|
110 | (2) |
|
6.3.2 Ceramic/Polymer Composites for Bone Reconstruction |
|
|
112 | (1) |
|
|
112 | (7) |
|
|
113 | (4) |
|
|
117 | (2) |
|
Chapter 7 Platelet-rich fibrin to incorporate bioactive graft materials |
|
|
119 | (24) |
|
|
119 | (1) |
|
7.2 Morphological and Biological Aspects of PRF |
|
|
120 | (2) |
|
7.3 Protocols for PRF Preparation |
|
|
122 | (1) |
|
7.4 PRF Embedding Nano-Porous Bioactive Ceramics |
|
|
122 | (6) |
|
7.5 Evidence of Tissue Healing |
|
|
128 | (4) |
|
|
132 | (11) |
|
|
133 | (9) |
|
|
142 | (1) |
|
Chapter 8 Nanostructured biomaterials embedding bioactive molecules |
|
|
143 | (16) |
|
|
143 | (1) |
|
8.2 Mesoporous Biomaterials as a Bioactive Delivery System |
|
|
144 | (3) |
|
8.2.1 Mesoporous Biomaterials Incorporation and Release of Bioactive Molecules |
|
|
145 | (2) |
|
8.3 Bioactive Molecules Enhancing Tissue Healing |
|
|
147 | (2) |
|
8.3.1 Bioactive Molecules for Osteogenesis |
|
|
147 | (1) |
|
8.3.2 Bioactive Molecules for Angiogenesis |
|
|
148 | (1) |
|
8.4 Bioactive Molecules to Inhibit Bacteria and Biofilms |
|
|
149 | (3) |
|
8.5 Bioactive Molecules for Analgesic and Antiinflammatory Effects |
|
|
152 | (1) |
|
8.6 Bioactive Molecules for Cancer Treatment |
|
|
153 | (1) |
|
|
154 | (5) |
|
|
154 | (4) |
|
|
158 | (1) |
|
Chapter 9 Functionally graded nanostructured biomaterials (FGNB) |
|
|
159 | (22) |
|
|
159 | (2) |
|
9.2 Bio-Inspired Functionally Graded Nanostructured Biomaterials (FGNB) |
|
|
161 | (2) |
|
9.3 FGNB Applied to Prosthodontics |
|
|
163 | (3) |
|
9.3.1 Metal-Ceramic Graded Restorations |
|
|
163 | (1) |
|
9.3.2 All Ceramic Graded Restorations |
|
|
164 | (2) |
|
9.4 FGNB Applied to Implants |
|
|
166 | (9) |
|
9.5 Concluding Remarks and Perspectives |
|
|
175 | (6) |
|
|
175 | (5) |
|
|
180 | (1) |
|
Chapter 10 Additive manufacturing of nanostructured bone scaffolds |
|
|
181 | (30) |
|
|
181 | (1) |
|
10.2 Bone Tissue Engineering and Regeneration |
|
|
182 | (2) |
|
10.3 Structure and Features of a Bone Scaffold |
|
|
184 | (2) |
|
10.4 Additive Manufacturing of Scaffolds |
|
|
186 | (4) |
|
10.5 Materials for Manufacturing Bone Scaffolds |
|
|
190 | (6) |
|
10.5.1 Bioceramic Materials |
|
|
190 | (2) |
|
10.5.2 Biocompatible Polymers |
|
|
192 | (1) |
|
10.5.3 Biocomposites for Bone Regeneration |
|
|
192 | (1) |
|
10.5.4 Biomaterials as Carriers of Growth Factors |
|
|
193 | (3) |
|
10.6 Nanostructured Bone Scaffolds Fabricated by AM |
|
|
196 | (4) |
|
10.7 Concluding Remarks and Perspectives |
|
|
200 | (11) |
|
|
201 | (9) |
|
|
210 | (1) |
Index |
|
211 | |