a comprehensive review on the advantages and application of nanotechnologies for biodetection including unique properties, methods, techniques for manufacturing, functionalization, and characterization.
1 Introduction
2 Nanomaterials for biodetection
3 Nanostructures for biodetection
4 Nanoprobes
5 Nanomaterials and nanostructures-based biosensor
6 Microfluidics and Nanofluidics
7 Theranostic nanotechnology
8 Application of nanotechnology in biodetection
9 Detection and analysis of single molecule, single cell, and single
nanoparticle
10 In vivo imaging and intracellular analysis
11 Nanotechnology-based molecular diagnostics: technology, industry and
clinical application
12 Nanotechnology-based immunodiagnostics: technology, industry and clinical
application
13 Liquid biopsy nanotechnology: technology, industry and clinical
application
14 Nanotechnology-based molecular imaging: technology, industry and clinical
application
15 Nanotechnology-based point-of-care-testing: technology, industry and
clinical application
16 Outlook on the clinical application of nanotechnology-based biodetection
Yanlian Yang is a Professor of the National Center for Nanoscience and Technology (NCNST). She received B.S. and M.S. degrees in chemistry from Shandong University and obtained her Ph.D. degree in physical chemistry from Peking University in 2002. Then, she worked as a postdoctoral researcher at Peking University for two years before she joined NCNST in 2004. She was a visiting scholar at Massachusetts Institute of Technology from 2007 to 2008. Her research interests include liquid biopsy based on peptide nanostructures, molecular mechanism, and modulation of peptide assembly structures associated with diseases, and the development of new nanocharacterization methods based on scanning probe microscopy.
Ling Zhu is currently an associate professor of the National Center of Nanoscience and Technology (NCNST). She received her B.S. degree in medicine at Chongqing Medical University in China in 2005 and her Ph.D. degree in molecular biology and biomedicine at University of the Basque Country in Spain in 2013. She joined NCNST in 2013. Her research interests focus on the design and synthesis of peptides and peptoids for molecular recognition, and biological detection based on nanomaterials and nanostructures.
Prof. Chunli Bai, a well-known chemist and leading scientist in nanoscience, is the president of the Chinese Academy of Sciences from 2013 to 2020. He graduated from the Department of Chemistry, Perking University in 1978 and received his M.Sc. and Ph.D. degrees from the CAS Institute of Chemistry in 1981 and 1985 respectively. From1985-1987, he worked with the California Institute of Technology, U.S.A., in the field of physical chemistry as a post-doctorate associate and visiting scholar. After he returned to China in 1987, he continued his research at the CAS Institute of Chemistry. From 1991 to 1992, he worked as a visiting professor at Tohoku University in Japan. His research areas include the structure and properties of polymer catalysts, X-ray crystallography of organic compounds, molecular mechanics and EXAFS research on electro-conducting polymers. He has a long list of scientific publications and has won more than twenty prestigious awards and prizes for his academic achievements.
Prof. Minghua Liu, working in Chemistry and nanoscience, He graduated from the Department of Chemistry, Nanjing University in 1986. Minghua Liu received his PhD degree in 1994 from Saitama University, Japan. He then joined the Institute of Physical and Chemical Research (RIKEN) as a Special Postdoctoral Researcher from 1994 to 1997. He joined the Institute of Photographic Chemistry, CAS, in 1998 and then the Institute of Chemistry, CAS, in 1999. In June 2013, he moved to National Center for Nanoscience and Technology, China. His research interests cover supramolecular chemistry, in particular, the chirality issues in self-assembled systems, soft organic nanomaterials, hybrid inorganic/organic nanomaterials. He is now on the advisory board of Advanced Science, Nanoscale Horizons. Chirality. He has published more than 300 papers in international peer-reviewed journals.
