Details latest strategies for the pursuit of effective Alzheimers management. Explores nutraceuticals and their pivotal role in managing Alzheimers disease. Discusses various potential therapies for the effective treatment of Alzheimers. Recent developments and advancements in the delivery of nutraceuticals are also explored.
The number of people living with dementia is expected to rise from 55 million in 2019 to 139 million in 2050, according to a report by WHO. Conventional drugs, while providing symptomatic relief, have often fallen short of halting the relentless progression of this neurodegenerative disorder. This new two-volume set represents a collective effort to delve into the potential of natures pharmacopeia in our battle against Alzheimers disease.
Volume 2: Strategies to Unlock the Brains Fortress offers a comprehensive exploration into the cutting-edge strategies for the pursuit of effective Alzheimers management. It first offers a holistic exploration of nutraceuticals and their pivotal role in managing Alzheimers disease, serving as a guide to the diverse array of neuro-nutraceuticals and providing insights into their mechanisms, efficacy, and potential integration into holistic Alzheimers management strategies. The book looks at natural antioxidant therapeutics, natural steroidal phytopharmaceuticals and Terpenes (aromatic compounds found in many plants), anti-apoptotic natural products, polysaccharides, neuro-protective role of vitamin D, and non-flavonoidal agents for the effective treatment of Alzheimers. Recent developments and advancements in the delivery of nutraceuticals are explored as well, looking at nanotechnology and advanced drug delivery systems for therapeutic interventions.
Volume 1: Targeting Key Pathological Pathways covers the pathophysiology and diagnosis of Alzheimers disease, its connection to gut microbiome, drug-induced Alzheimers disease, and more, also discussing the vast potential of nutraceuticals in managing Alzheimers disease. It explores a plethora of medicinal plants and their secondary metabolites that show promise in treating this devastating condition.
Together, these volumes not only reflect the current state of knowledge but also pave the way for future exploration in the field.
PART I: NUTRACEUTICALS: HOLISTIC APPROACHES TO ALZHEIMERS MANAGEMENT
1.
Emergent Natural Antioxidant Therapeutics to Cope with Oxidative Stress in
Alzheimers Disease
2. Exploring Beta Secretase Inhibitors as the Evergreen
Drug Target for Alzheimers Disease: Calling Herbal Therapies to the Rescue
3. Role of Natural Steroidal Phytopharmaceuticals in the Management of
Alzheimers Disease
4. Potential Role of Terpenes in the Management of
Alzheimers Disease
5. Anti-Apoptotic Natural Products for the Management of
Alzheimers Disease
6. Potential Natural Polysaccharides for the Management
of Alzheimers Disease
7. Neuro-Protective Role of Vitamin D in Alzheimers
Disease
8. Role of Non-Flavonoidal Agents in Alzheimers Disease PART II:
RECENT DEVELOPMENTS AND ADVANCEMENTS IN THE DELIVERY OF NUTRACEUTICALS ACROSS
BLOOD-BRAIN-BARRIER
9. Drug Delivery Strategies for Drug Targeting for
Alzheimers Disease
10. Nanocargos for Efficient Delivery of Nutraceuticals
Across Blood-Brain Barrier
11. Recent Advancement in Strategies for Delivery
of Neuronutraceuticals to the Brain
Varinder Singh, PhD, is an Assistant Professor of Pharmaceutical Sciences and Technology at Maharaja Ranjit Singh Punjab Technical University, Bathinda, Punjab, India. He is well versed in the fields of natural product chemistry (isolation and characterization of bioactive natural compounds), drug discovery, and pharmacology. He has a strong record of publications in high-impact peer-reviewed journals, with many of his papers cited extensively in the field of natural products.
Amit Kumar, PhD, is an Associate Professor at Chitkara College of Pharmacy, Chitkara University, Punjab, India. He has 12 years of teaching and research experience and has published more than 20 research articles in international journals. He has also filed three patents. His area of research includes neuroprotective drug development and elucidating pathological features of diseases.
Parul Sood, PhD, is an Associate Professor at Chitkara School of Pharmacy, Chitkara University, Himachal Pradesh, India. She has more than 14 years of professional experience in teaching and research. Her area of specialization and research is exploring herbal plants for the treatment of various neurological disorders including, Alzheimers disease, as well as pharmacognostical and phytochemical evaluation, and standardization of herbal drugs and herbal drug formulation development.
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