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E-grāmata: Neuroscience of Addiction

4.36/5 (66 ratings by Goodreads)
(University of Texas, Dallas)
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Neuroscience of AddictionPalielināt
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"This book answers a growing need for accessible information on the neuroscience of addiction. In the past decade neuroscientific research has greatly advanced our understanding of the brain mechanisms of addiction, however this information still remainslargely confined to scientific outlets. As legislation continues to evolve and the stigma surrounding addiction persists, new findings on the impact of substances on the brain are an important public health issue. Francesca Filbey gives readers an overview of research on addiction including classic theories as well as current neuroscientific studies. A variety of textual supports - including keywords, a glossary, learning objectives and review questions - help students better reinforce their reading and make the text a ready-made complement to undergraduate and graduate courses on addiction"--Provided by publisher.

Recenzijas

'Francesca Filbey's book, intended for an interdisciplinary audience, bridges concepts in neuroscience with the clinical presentation of addiction. It is logically organized into chapters that describe each progressive stage of the addiction cycle in terms of theoretical perspectives, preclinical models, and human behavior. The text combines classic knowledge with current findings from novel methodologies, particularly in human neuroimaging, that facilitates the understanding of addiction as a brain disorder.' Eric J. Nestler, Icahn School of Medicine at Mount Sinai 'The Neuroscience of Addiction provides an outstanding synthesis of the current state of knowledge about the stages of addiction along with a review and explanation of the research that led to current concepts in the field. It is an excellent text for neuroscience students entering the field.' Edythe D. London, Brain Research Institute, University of California, Los Angeles

Papildus informācija

Combines classic theories with current neuroscientific studies to explain the addiction cycle, focusing on neuroimaging studies and applications.
List of Plates
xi
List of Figures
xii
List of Tables
xvi
Preface xvii
1 What is Addiction?
1(20)
Learning Objectives
1(1)
Introduction
1(3)
The Phenomenology of Substance Use Disorders
4(1)
The Demography of Addiction
5(1)
The Stigma of Addiction
5(1)
The Diagnosis of Addiction
6(3)
A Brain Disease Model of Addiction
9(3)
Non-Drug Addictions
12(2)
Summary Points
14(1)
Review Questions
14(1)
Further Reading
14(1)
Spotlight
15(1)
References
16(5)
2 Human Neuroscience Approaches Toward the Understanding of Addiction
21(13)
Learning Objectives
21(1)
Introduction
21(1)
Measuring the Brain's Electrical Activity
22(2)
Visualizing the Brain's Structure and Function
24(3)
Biochemical Imaging
27(1)
Limitations of Neuroimaging Research
28(1)
Summary Points
29(1)
Review Questions
29(1)
Further Reading
29(1)
Spotlight 1
30(2)
Spotlight 2
32(1)
References
32(2)
3 Brain-Behavior Theories of Addiction
34(13)
Learning Objectives
34(1)
Introduction
34(1)
The Incentive-Sensitization Theory
35(1)
The Allostatic Model: Dysregulation in Homeostasis
36(2)
The Impaired Response Inhibition and Salience Attribution (iRISA) Syndrome Model
38(2)
The Future of Brain-Behavior Theories of Addiction
40(2)
Summary Points
42(1)
Review Questions
42(1)
Further Reading
42(1)
Spotlight
43(2)
References
45(2)
4 From the Motivation to Initiate Drug Use to Recreational Drug Use: Reward and Motivational Systems
47(17)
Learning Objectives
47(1)
Introduction
47(1)
Reward and Motivational Systems Guide the Direction of Behavior
48(3)
Predicting Rewards: Evidence for the Primary Role of Dopamine
51(2)
Final Common Pathway: All Drugs Lead to One
53(2)
Is Addiction a Reward Deficiency Syndrome?
55(1)
Corticostriatal Circuitry and Effort-Reward Imbalance
56(1)
Role of Memory Systems
56(2)
Summary Points
58(1)
Review Questions
58(1)
Further Reading
59(1)
Spotlight
60(1)
References
61(3)
5 Intoxication
64(17)
Learning Objectives
64(1)
Introduction
64(2)
Drug Pharmacodynamics
66(1)
Actions of Addictive Drugs
66(2)
Brain Mechanisms of Intoxication: Evidence From Neuroimaging Pharmacological Studies
68(5)
Modulators of Intoxication: Challenges in Human Research
73(2)
Summary Points
75(1)
Review Questions
76(1)
Further Reading
76(1)
Spotlight
76(2)
References
78(3)
6 Withdrawal
81(17)
Learning Objectives
81(1)
Introduction
81(1)
What Does Withdrawal Look Like?
82(3)
Acute Withdrawal Symptoms and Associated Neural Mechanisms
85(2)
Protracted Withdrawal Symptoms and Associated Neural Mechanisms
87(1)
Electrophysiological Mechanisms of Withdrawal
88(2)
A Model of Opposing Mechanisms: Between-System Response to Drugs
90(1)
Summary Points
91(1)
Review Questions
92(1)
Further Reading
92(1)
Spotlight 1
93(1)
Spotlight 2
94(1)
References
94(4)
7 Craving
98(16)
Learning Objectives
98(1)
Introduction
98(1)
Cue-Elicited Craving Paradigms and Associated Neural Mechanisms
99(2)
Neurophysiological Underpinnings of Craving
101(1)
Contextual Cues
102(1)
Do Drugs Hijack the Reward Circuitry of the Brain?
103(2)
Greater Craving or Greater Attention?
105(1)
Neuromolecular Mechanisms
106(1)
Summary Points
107(1)
Review Questions
107(1)
Further Reading
108(1)
Spotlight
108(2)
References
110(4)
8 Impulsivity
114(16)
Learning Objectives
114(1)
Introduction
114(2)
Neuropharmacology of Impulsivity
116(1)
Is Impulsivity Pre-existing or Drug Induced?
117(3)
Risky Decision Making
120(1)
Inhibitory Control
121(2)
Delay Discounting of Reward
123(2)
Summary Points
125(1)
Review Questions
125(1)
Further Reading
126(1)
Spotlight
127(1)
References
128(2)
9 Impacts of Brain-Based Discoveries on Prevention and Intervention Approaches
130(18)
Learning Objectives
130(1)
Introduction
130(2)
Pharmacological Approaches
132(3)
Behavioral Approaches
135(2)
Combined Approaches
137(1)
Treatment Outcomes
138(3)
Summary Points
141(1)
Review Questions
141(1)
Further Reading
141(1)
Spotlight 1
142(1)
Spotlight 2
143(1)
References
144(4)
1 Conclusions
148(14)
Learning Objectives
148(1)
Introduction
148(1)
Risk Factors Inform Better Prevention and Intervention
149(1)
Addiction Endophenotypes
150(5)
Sex Differences in Addiction
155(1)
The Question of Causality
156(1)
General Conclusions
157(2)
Summary Points
159(1)
Review Questions
159(1)
Further Reading
160(1)
Spotlight 1
161(1)
Spotlight 2
162(1)
References 162(3)
Glossary 165(8)
Index 173
Francesca Mapua Filbey is a Professor of Cognition and Neuroscience, and Bert Moore Endowed Chair of BrainHealth, for the School of Behavioral and Brain Sciences at the University of Texas, Dallas. She conducts research aimed to understand the biobehavioral mechanisms of addictive disorders towards the improvement of early detection and intervention.
Biežāk uzdotie jautājumi par e-grāmatām Biežāk uzdotie jautājumi par e-grāmatām
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