E-grāmata: Neurosurgical Aspects of Craniosynostosis

I Introduction.- 1 Historical perspective on the evolution of the
techniques and role of the neurosurgeon.- 2 Embryology:  Skull growth,
posterior fossa growth: what is important for the neurosurgeon.- 3 Genetics
of craniosynostoses : what is important for the neurosurgeon.- 4 Animal
models : what is important for the neurosurgeon.- 5 Analysis of postnatal
skull shape and brain growth: what is important for the neurosurgeon.- II
Clinical aspects.- 6 Clinical diagnosis: what is important for the
neurosurgeon.- 7 Sagittal sutures synostosis: key points for the
neurosurgeons, management principles (diagnosis, surgical principles and
their rationale, timing).- 8 Metopic sutures synostosis: key points for the
neurosurgeons, management principles (diagnosis, surgical principles and
their rationale, timing).- 9 Coronal sutures synostosis: key points for the
neurosurgeons, management principles (diagnosis, surgical principles and
their rationale, timing).- 10 Sphenopalatine synostosis: key points for the
neurosurgeons, management principles (diagnosis, surgical principles and
their rationale, timing).- 11 Lambdoid sutures synostosis: key points for the
neurosurgeons, management principles (diagnosis, surgical principles and
their rationale, timing).- 12 Multiple sutures synostosis: key points for the
neurosurgeons management principles (diagnosis, surgical principles and their
rationale, timing).- III CSF and hemodynamics alterations in
craniosynostoses.- 13 Hydrocephalus.- 14 Pericerebral effusions.- 15 Cerebral
perfusion in craniosynostoses           .- 16 What perfusion explorations ?
US, NIRS, TCD, ASL etc.- 17 Venous anomalies and craniosynostosis.- 18
Craniocerebral disproportion and raised ICP in craniosynostoses.- 19
Cerebellar tonsils herniation in craniosynostoses. 20 Syringomyelia in
craniosynostoses.- 21 Surgical indications: when is surgery necessary.- 22
Controversies in the indications for surgery (surgery vs no surgery, esthetic
indication vs functional indication ).- III The multidisciplinary team and
the neurosurgeon.- 23 The role of the neurosurgeon in the multidisciplinary
team.- 24 Antenatal diagnosis.- 25 What to ask to the radiologist in
craniosynostoses?.- 26 What to ask to the ENT in craniosynostoses?.- 27 What
to ask to the ophthalmologist in craniosynostoses?.- 28 What to ask to the
maxillofacial surgeon in craniosynostoses?.- 29 What to ask to the
orthodontist in craniosynostoses?.- 30 What to ask to the genetist in
craniosynostoses?.- 31 What to ask to the pediatrician in craniosynostoses.-
32 What to ask to the psychologist, Psychological aspects.- IV Technical
aspects.- 33 Role of 3D volummetry and 3D planning.- 34 Anesthesiological
issues: what the neurosurgeon should.- 35 Hemostasis and transfusion in
craniosynostoses surgery.- 36 Osteotomy principles, tools and hardware
presentation.- 37 Resorbable and non resorbable materials in in
craniosynostoses surgery.- V Surgical procedures.- 38 Fixed Posterior vault
remodeling.- 39 Posterior vault distraction.- 40 Anterior vault remodeling.-
41 Spring assisted vault remodeling.- 42 Endoscopic approaches.- 43 Role of
the post-operative helmet.- 44 technical tips for surgery  in older
children.- 45 Controversies in the type of surgery (What technique in which
case ? the heterogeneity of the management of craniosynostoses  minimally
invasive vs total vault etc ).- VI Surgical  Steps(How I do it).- 46 surgery
for sagittal suture synostosis: key points for the neurosurgeons.- 47
Endoscopic.- open vault.- 48 old children.- 49 distraction.- 50 Spring.- VII
surgery for metopic suture synostosis: key points for the neurosurgeons.- 51
open vault.- 52 Endoscopic-surgery for coronal suture synostosis: key points
for the neurosurgeons.- 53 open vault.- 54 Endoscopic.- 55 distraction.- 56
surgery for lambdoid suture synostosis: key points for the neurosurgeons.- 57
surgery for multiple sutures synostosis: key points for the neurosurgeons
(strategy and timing of the procedures).- 58 Foramen magnum decompression in
craniosynostosis.- 59 role of ETV in craniosynostoses.- 60 VP shunt in
craniosynostoses.- 61 Post-operative management.- VIII RESULTS.- 62 What
evaluation tools in craniosynostoses ?.- 63 Mortality, morbidity and
complications avoidance.- 64 Cognitive aspects and outcome.- 65 Functional
results.- 66 Impact of genetics on the outcome.- 67 Quality of life.- 68
Impact of post-surgical helmet therapy on cognitive outcomes.- 60 Long
Follow-up results.

Federico Di Rocco is full Professor of Neurosurgery and Chairman of the neurosurgical residency program at the University of Lyon 1 (France). He is  Chairman of the Pediatric Neurosurgical Department at the Hōpital Femme Mčre Enfant of Lyon and Co-Chairman of the  of the Pediatric Neurosurgical Department at the China International Neuroscience Institute, Beijing . He is member of the Executive Board of International Society for Pediatric Neurosurgery (ISPN),  European Society for Pediatric Neurosurgery (ESPN), the Société de Neurochirurgie de Langue Franēaise (SNCLF) and the Pediatric Committee of the Wolrd Federaion of Neurosurgical Societies (WFNS) and of the European Association of  Neurosurgical Societies  (EANS). He is currently the Director of the French National Referral Center for Craniosynostosis of Lyon, member of the European Rare Disease Network ERN-CRANIO and past Secretary of the European Society of Craniofacial Surgery (ESCFS). Prof Di Rocco is author of more than 250 articles published in peer reviewed international journals and chapters in neurosurgical textbooks. 





John R. W. Kestle is a pediatric neurosurgeon and clinical researcher in craniosynostosis and pediatric hydrocephalus. He trained in Neurosurgery in Toronto and in Clinical Epidemiology at McMaster University. He began his career at the University of British Columbia in 1992. In 1998, he joined the faculty at the University of Utah and Primary Childrens Hospital in Salt Lake City, where he became Professor of Neurosurgery, Chief of the Division of Pediatric Neurosurgery and Neurosurgery Residency Program Director. He has served as Treasurer and as Scientific Chair of the International Society for Pediatric Neurosurgery, Chair of the Editorial Board for the Journal of Neurosurgery:Pediatrics, and as Chair American Board of Pediatric Neurosurgery. His clinical practice focuses on hydrocephalus and craniosynostosis. His research is in craniosynostosis and hydrocephalus and he founded and Chaired the Hydrocephalus Clinical Research Network (hcrn.org) and the Synostosis Research Group (SynRG). He is currently Professor of Neurosurgery and Vice Chair, Clinical Research in the Department of Neurosurgery at the University of Utah, USA.