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Occupational Health and Safety in the Care and Use of Nonhuman Primates [Mīkstie vāki]

  • Formāts: Paperback / softback, 180 pages, height x width: 229x152 mm
  • Izdošanas datums: 13-Jul-2003
  • Izdevniecība: National Academies Press
  • ISBN-10: 030908914X
  • ISBN-13: 9780309089142
  • Mīkstie vāki
  • Cena: 54,72 €
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  • Formāts: Paperback / softback, 180 pages, height x width: 229x152 mm
  • Izdošanas datums: 13-Jul-2003
  • Izdevniecība: National Academies Press
  • ISBN-10: 030908914X
  • ISBN-13: 9780309089142
The field of occupational health and safety constantly changes, especially as it pertains to biomedical research. New infectious hazards are of particular importance at nonhuman-primate facilities. For example, the discovery that B virus can be transmitted via a splash on a mucous membrane raises new concerns that must be addressed, as does the discovery of the Reston strain of Ebola virus in import quarantine facilities in the U.S. The risk of such infectious hazards is best managed through a flexible and comprehensive Occupational Health and Safety Program (OHSP) that can identify and mitigate potential hazards.

Occupational Health and Safety in the Care and Use of Nonhuman Primates is intended as a reference for vivarium managers, veterinarians, researchers, safety professionals, and others who are involved in developing or implementing an OHSP that deals with nonhuman primates. The book lists the important features of an OHSP and provides the tools necessary for informed decision-making in developing an optimal program that meets all particular institutional needs.



Table of Contents



Front Matter Executive Summary 1. Introduction and Overview 2. Background and Context for Occupational Health and Safety in the Care and Use of Nonhuman Primates 3. Identifying Infectious Hazards Associated with the Use of Nonhuman Primates in Research 4. Identifying Noninfectious Hazards 5. Risk Assessment: Evaluating Risks to Human Health and Safety 6. Occupational Health and Safety Regulations and Recommendations Applicable to Nonhuman-Primate Research Facilities 7. Risk Management: The Principles Underlying the Design and Implementation of an Occupational Health and Safety Plan 8. Personnel Qualifications, Training, and Continuing Education 9. Postexposure Medical Treatment in Nonhuman-Primate Facilities References Appendix A: Workshop Speakers Appendix B: Committee Member Biographies
Executive Summary 1(4)
Introduction and Overview
4(5)
Occupational Health and Safety Program
5(1)
Overview
6(3)
Background and Context for Occupational Health and Safety in the Care and Use of Nonhuman Primates
9(12)
Introduction
9(1)
Intent of this Report
10(1)
Implementing the Occuptional Health and Safety Program
11(3)
Hazards Associated with Nonhuman-Primate Behavior
14(5)
Risks and Risk Reduction Associated with Environmental Enrichment
19(2)
Identifying Infectious Hazards Associated with the Use of Nonhuman Primates in Research
21(38)
Viral Diseases
23(17)
Bacterial Diseases
40(7)
Protozoan Parasites
47(4)
Metazoan Parasites
51(4)
Other Agents
55(2)
Summary
57(2)
Identifying Noninfectious Hazards
59(9)
Physical Hazards
60(5)
Chemical Hazards
65(3)
Risk Assessment: Evaluating Risks to Human Health and Safety
68(15)
Background
68(1)
The Process of Risk Assessment
69(11)
Risk of Occupational Injuries and Exposures at National Primate Research Centers
80(3)
Occupational Health and Safety Regulations and Recommendations Applicable to Nonhuman-Primate Research Facilities
83(11)
Federal Occupational Health and Safety Requirements
83(6)
State Occupational Health and Safety Requirements
89(1)
Useful References
90(4)
Risk Management: the Principles Underlying the Design and Implementation of an Occupational Health and Safety Plan
94(26)
Administrative Procedures
96(1)
Facility Design and Operation
97(1)
Exposure-Control Methods
98(4)
Education and Training
102(1)
Occupational Health
102(3)
Tuberculosis Testing
105(1)
Equipment Performance
105(2)
Information Management
107(1)
Emergency Procedures
107(1)
Program Evaluation
108(12)
Personnel Qualifications, Training, and Continuing Education
120(15)
Introduction
120(1)
Personnel Qualifications
121(2)
Training
123(10)
Continuing Education
133(1)
Recordkeeping
134(1)
Postexposure Medical Treatment in Nonhuman-Primate Facilities
135(12)
Defining Exposure Risk
136(1)
Scope of Potential Infectious Agents in Nonhuman Primates
136(1)
Defining Routes of Exposure
137(2)
Determining Appropriate Postexposure Medical Management
139(1)
First Aid after Exposures to Nonhuman Primates
140(1)
Medical Evaluation and Followup
141(3)
B Virus Exposure
144(1)
Exposure to Simian Immunodeficiency Viruses
145(1)
Other Retroviruses
146(1)
Recombinant-Vaccinia Research
146(1)
REFERENCES
147(14)
APPENDICES
A Workshop Speakers
159(2)
B Committee Member Biographies
161


Committee on Occupational Health and Safety in the Care and Use of Nonhuman Primates, National Research Council