Now in paperback, this text covers the dramatic developments that have occurred in basic neuroscience and clinical research in cognitive neurology and dementia. The text is based on the clinical approach to the patient, and provides essential knowledge that is fundamental to clinical practice.
Now in paperback, the Oxford Textbook of Cognitive Neurology and Dementia covers the dramatic developments that have occurred in the basic neuroscience and clinical research in both cognitive neurology and dementia in an integrated fashion. The text is firmly based on the clinical approach to the patient with cognitive impairment and dementia, while also providing the essential background scientific knowledge that is fundamental to clinical practice.
Divided into three main sections, this book combines the basic science (Section 1) with different types of cognitive deficit or neuropsychological presentation (Section 2), and disease specific chapters (Section 3).
With contributions from a range of international experts, this is essential reading for clinicians with an interest in cognition and dementia including neurologists, geriatricians and psychiatrists. It provides a powerful means of bringing together different aspects of conceptual understanding and factual knowledge, in a way that usually can only come after many years in the field.
| Abbreviations |
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ix | |
| Contributors |
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xv | |
| Section 1 Normal cognitive function |
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1 Historical aspects of neurology |
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3 | (14) |
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2 Functional specialization and network connectivity in brain function |
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17 | (10) |
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27 | (12) |
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39 | (12) |
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51 | (8) |
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59 | (10) |
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7 The basal ganglia in cognitive disorders |
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69 | (12) |
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8 Principles of white matter organization |
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81 | (10) |
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9 Neurochemistry of cognition |
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91 | (14) |
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| Section 2 Cognitive dysfunction |
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10 Bedside assessment of cognition |
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105 | (8) |
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11 Neuropsychological assessment |
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113 | (10) |
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12 Acquired disorders of language and speech |
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123 | (12) |
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135 | (12) |
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14 Vision and visual processing deficits |
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147 | (14) |
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15 Disorders of attentional processes |
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161 | (12) |
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173 | (10) |
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17 Acquired calculation disorders |
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183 | (6) |
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18 Disorders of reading and writing |
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189 | (8) |
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19 Neuropsychiatric aspects of cognitive impairment |
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197 | (14) |
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| Section 3 Cognitive impairment and dementia |
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20 Epidemiology of dementia |
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211 | (10) |
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21 Assessment and investigation of the cognitively impaired adult |
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221 | (10) |
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22 Delirium, drugs, toxins |
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231 | (8) |
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239 | (14) |
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253 | (22) |
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25 Vascular cognitive impairment |
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275 | (10) |
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26 Cerebral amyloid angiopathy and CNS vasculitis |
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285 | (10) |
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27 Cognition in multiple sclerosis |
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295 | (4) |
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28 Autoimmune encephalitis |
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299 | (16) |
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29 Pathology of degenerative dementias |
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315 | (14) |
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30 Genetics of degenerative dementias |
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329 | (10) |
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31 Other genetic causes of cognitive impairment |
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339 | (14) |
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32 Changing concepts and new definitions for Alzheimer's disease |
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353 | (8) |
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33 Presentation and management of Alzheimer's disease |
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361 | (20) |
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34 Primary progressive aphasia |
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381 | (10) |
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35 Frontotemporal dementia |
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391 | (8) |
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36 Dementia with Lewy bodies and Parkinson's disease dementia |
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399 | (14) |
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37 Corticobasal degeneration, progressive supranuclear palsy, multiple system atrophy, argyrophilic grain disease, and rarer neurodegenerative diseases |
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413 | (12) |
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425 | (10) |
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39 Traumatic brain injury |
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435 | (18) |
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40 Neurosurgery for cognitive disorders |
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453 | (10) |
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41 Cognition in severe mental illness: Schizophrenia, bipolar disorder, and depression |
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463 | (8) |
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| Index |
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471 | |
Masud Husain is Professor of Neurology & Cognitive Neuroscience at the Nuffield Department of Clinical Neurosciences, University of Oxford, UK. He read Physiological Sciences/Medicine (1981-84) at Oxford before completing his PhD in 1987. He held a Harkness Fellowship and was a postdoctoral fellow at MIT, prior to returning to Oxford to finish his clinical degree. After Neurology training in London, he held a joint appointment as Consultant Neurologist and Wellcome Trust Senior Fellow (2000-12). In 2013, he was awarded a Principal Fellowship by The Wellcome Trust and moved to Oxford where he is a Professorial Fellow at New College. Previously he was Professor of Clinical Neurology at UCL & The National Hospital for Neurology & Neurosurgery, London and Deputy Director of the UCL Institute of Cognitive Neuroscience.
Jonathan M. Schott is Professor of Neurology, at the Dementia Research Centre, Department of Neurodegenerative Diseases, UCL Institute of Neurology, UK. He was awarded a First Class BSc in Basic Medical Sciences with Physiology (Imperial College, 1993), gained Honours (in surgery) at medical finals, and was awarded the Malcolm Morris Memorial Prize (1996). Jonathan joined the Dementia Research Centre (DRC), Institute of Neurology (2001-5), where he was awarded his MD (UCL, 2004), for investigation of the role of serial magnetic resonance imaging as a tool for tracking the progressions of Alzheimer's disease (AD) and in aiding diagnosis. After completing his clinical training, he rejoined the DRC as HEFCE/NHS Senior Lecturer/Honorary Consultant at the Institute of Neurology, UCL (2009 - ).
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