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E-grāmata: Oxford Textbook of Neuromuscular Disorders

Edited by (Consultant Neurologist, Department of Clinical Neurology, Department of Neurosciences, John Radcliffe Hospital, Oxford, UK), Edited by (Consultant Neurologist, Department of Clinical Neurology, Department of Neurosciences, John Radcliffe Hospita)
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Part of the Oxford Textbooks in Clinical Neurology series, the Oxford Textbook of Neuromuscular Disorders covers the scientific basis, clinical diagnosis, and treatment of neuromuscular disorders with a particular focus on the most clinically relevant disorders. The book is organized into seven sections, starting with the general approach to the patient with neuromuscular disorders and then focusing on specific neuromuscular conditions affecting the peripheral nervous system from its origins at the spinal cord anterior horn on its outward course to their effector muscles and the inbound sensory pathways. Chapters on specific neuromuscular conditions are illustrated with typical case histories and their presenting features, allowing readers to put rarer conditions into their clinical context more easily. The concurrent online version allows access to the full content of the textbook, contains links from the references to primary research journal articles, allows full text searches, and provides access to figures and tables that can be downloaded to PowerPointRG.
This textbook will serve as a useful reference for neurologists and specialist trainees in neurology, neuroscientists, neurophysiologists, and other healthcare professionals.

Papildus informācija

Includes 12 months access to the online version
Abbreviations to Contributors xv
SECTION 1 Approach to the Patient
1 Eliciting the history
3(6)
David Hilton-Jones
Martin R. Turner
2 Genetic considerations
9(6)
David Hilton-Jones
Martin R. Turner
3 Examination
15(10)
David Hilton-Jones
Martin R. Turner
SECTION 2 Anterior Horn
4 Amyotrophic lateral sclerosis
25(13)
Kevin Talbot
Martin R. Turner
5 Spinal muscular atrophy and hereditary motor neuropathy
38(10)
Dirk Baumer
Kevin Talbot
6 Kennedy disease
48(3)
Christopher Grunseich
Kenneth Fischbeck
7 Poliomyelitis
51(10)
Robin S. Howard
SECTION 3 Peripheral Nerve: Inherited
8 Charcot--Marie--Tooth disease
61(14)
Mary M. Reilly
Alexander M. Rossor
9 Hereditary sensory and autonomic neuropathies
75(7)
Michaela Auer-Grumbach
10 Familial amyloid polyneuropathy
82(3)
Violaine Plante-Bordeneuve
11 Inherited metabolic neuropathies
85(8)
Lionel Ginsberg
SECTION 4 Peripheral Nerve: Acquired
12 Mononeuropathy
93(27)
Neil G. Simon
Matthew C. Kiernan
13 Multiple mononeuropathies
Eleanor A. Marsh
J. Gareth Llewelyn
14 Plexopathy
120(12)
David L. H. Bennett
Mohamed Mahdi-Rogers
15 Polyneuropathies: axonal
132(11)
Camiel Verhamme
Ivo N. van Schaik
16 Polyneuropathies: demyelinating
143(15)
Pieter A. van Doom
Judith Drenthen
17 Diabetic neuropathy
158(9)
Stephen A. Goutman
Andrea L. Smith
Stacey A. Sakowski
Eva L. Feldman
18 Peripheral nerve hyperexcitability disorders
167(8)
David Hilton-Jones
SECTION 5 Neuromuscular Junction: Inherited and Acquired
19 Inherited myasthenic syndromes
175(9)
Jacqueline Palace
Sarah Finlayson
20 Myasthenia gravis
184(11)
Saiju Jacob
Stuart Viegas
David Hilton-Jones
21 The Lambert-Eaton myasthenic syndrome
195(10)
Maarten J. Titulaer
Jan J. G. M. Verschuuren
SECTION 6 Muscle
22 The dystrophinopathies
205(14)
Kevin M. Flanigan
23 Limb-girdle muscular dystrophies
219(10)
Fiona L.M. Norwood
Kate Bushby
24 The congenital muscular dystrophies
229(14)
Emma Clement
Heinz Jungbluth
25 The myotonic dystrophies
243(11)
Chris Turner
David Hilton-Jones
26 Facioscapulohumeral muscular dystrophy
254(10)
Elly L. van der Kooi
Silvere van der Maarel
Baziel G.M. van Engelen
27 Distal and myofibrillar myopathies
264(13)
Bjarne Udd
28 Congenital/ultrastructural myopathies
277(11)
Gianina Ravenscroft
Nigel F. Clarke
Nigel G. Laing
29 Metabolic myopathies
288(14)
Mette C. Ørngreen
John Vissing
30 Mitochondrial cytopathies
302(14)
Gerald Pfeffer
Patrick F. Chinnery
31 Skeletal muscle channelopathies
316(10)
Emma Matthews
Michael G. Hanna
32 Idiopathic inflammatory myopathies
326(12)
Marianne de Visser
Anneke J. van der Kooi
33 Drug-induced neuromuscular disorders
338(9)
Zohar Argov
34 Endocrine myopathies
347(10)
Merrilee Needham
Frank Mastaglia
SECTION 7 Acute Neuromuscular Consults
35 The neuromuscular emergency consult
357(3)
Peter Connick
Maxwell S. Damian
36 Critical care of neuromuscular disorders
360(7)
Maxwell S. Damian
Index 367
Dr David Hilton-Jones is Consultant Neurologist at the University of Oxford and John Radcliffe Hospital, Oxford UK and Clinical Director, Muscular Dystrophy Campaign Muscle and Nerve Centre. Dr Hilton-Jones developed an interest in muscle diseases when working for Dr John Morgan-Hughes at Queen Square, London before spending a year training with the late Professor George Karpati in Montreal. He was appointed as a consultant neurologist in Oxford, UK with the intention of developing services for patients with neuromuscular disorders and is now Clinical Director of the Oxford Muscle & Nerve Centre, supported by the Muscular Dystrophy Campaign. He is also Clinical Director of the Oxford Myasthenia Centre, supported by the Myasthenia Gravis Association. His major interest is in combining clinical practice and research.





Dr Martin R. Turner is a Consultant Neurologist and Senior Clinician Scientist within the Oxford University Nuffield Department of Clinical Neurosciences. His research focuses on understanding the variation in the clinical presentations of amyotrophic lateral sclerosis/motor neuron disease (ALS/MND) and finding biomarkers for them. In particular Dr Turner is interested in the role of the brain in ALS/MND, and using advanced neuroimaging to explore structure and function through his affiliation with the Oxford Centre for the Functional Magnetic Resonance Imaging of the Brain: FMRIB.