This volume of fascinating mathematical brainteasers demonstrates how a combination of new discoveries in developmental biology and their associated modelling and computational techniques has and will stimulate relevant advances in modern biology.
Pattern Formation in Morphogenesis is a rich source of interesting and challenging mathematical problems. The volume aims at showing how a combination of new discoveries in developmental biology and associated modelling and computational techniques has stimulated or may stimulate relevant advances in the field. Finally it aims at facilitating the process of unfolding a mutual recognition between Biologists and Mathematicians of their complementary skills, to the point where the resulting synergy generates new and novel discoveries. It offers an interdisciplinary interaction space between biologists from embryology, genetics and molecular biology who present their own work in the perspective of the advancement of their specific fields, and mathematicians who propose solutions based on the knowledge grasped from biologists.
Recenzijas
From the reviews:
The current book may be a good start to explore the subject. There are some 20 relatively short papers presenting different possible angles, approaches, and models for many different aspects of morphogenetic phenomena. The seeds for these papers were planted during a workshop on the subject at the IHES in Bures-sur-Yvette (France) in 2010. The idea of this workshop was precisely to create an environment in which biologists and mathematicians could communicate on this particular subject. (A. Bultheel, The European Mathematical Society, December, 2012)
Preface.- Why Would a Mathematician Care About Embryology? M.Gromov.-
PART I.BIOLOGICAL BACKGROUND.- Preface to the Biological Part.- Pattern
Formation in Regenerating Tissues. A.Hoffmann and P.A. Tsonis.- Gradients and
Regulatory Networks of Wnt Signalling in Hydra Pattern Formation. T.W.
Holstein.- Modeling of Planar Cell Polarity Signaling. J.D. Axelrod.-
Integrated Molecular Circuits for Stem Cell Activity in Arabidopsis Roots. B.
Scheres.- The Mechanics of Tissue Morphogenesis. T. Lecuit.- Small Regulatory
RNAs and Skeletal Muscle Cell Differentiation. A. Harel-Bellan, A.Polesskaya,
I.Naguibneva, M.Ameyar-Zazoua, C.Degerny, J.Kropp, N.Nonne, M.Souidi,
G.Kratassiouk, G.Pinna, L.L.Pritchard.- Pattern Formation in Sea Urchin
Endomesoderm as Instructed by Gene Regulatory Network Topologies. I.S. Peter
and E.H. Davidson.- PART II. MATHEMATICAL MODELS.- Modelling Oscillator
Synchronisation During Vertebrate Axis Segmentation. P.J. Murray, P.K. Maini,
and R.E. Baker.- Pattern Formation in Hybrid Models of Cell Populations. N.
Bessonov, P. Kurbatova, V. Volpert.-An Integrative Approach to the Analysis
of Pattern Formation in Butterfly Wings Experiments and Models. T.
Sekimura.- Modeling Morphogenesis in Multicellular Structures with Cell
Complexes and L-systems. P. Prusinkiewicz and B. Lane.- Multistability and
Hysteresis-based Mechanism of Pattern Formation in Biology. A.
Marciniak-Czochra and A. Köthe.- How to knock out feedback Circuits in Gene
Networks? H. Gruber, A. Richard, C. Soulé.- Formation of Evolutionary
Patterns in Cancer Dynamics. M. Delitala and T. Lorenzi.- How Cell Decides
Between Life and Death: Mathematical Modeling of Epigenetic Landscapes of
Cellular Fates. A. Zinovyev, L. Calzone, S.Fourquet and E. Barillot.- PART
III. IDEAS, HYPOTHESIS, SUGGESTIONS.- From Hydra to Vertebrates: Models for
the Transition from Radial- to Bilateral-symmetric Body Plans, H. Meinhardt.-
Cell Division and Hyperbolic Geometry. M. Gromov.- Formalistic Representation
of the Cellular Architecture in the Course of Plant Tissue Development. I.V.
Rudskiy.- The Geometry of Morphogenesis and the Morphogenetic Field Concept.
N.Morozova and M.Shubin.- Randomness and Geometric Structures in Biology. V.
Capasso.
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