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E-grāmata: Peptides: Biology and Chemistry

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  • Formāts: PDF+DRM
  • Sērija : Chinese Peptide Symposia
  • Izdošanas datums: 11-Apr-2006
  • Izdevniecība: Springer
  • Valoda: eng
  • ISBN-13: 9780306468803
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  • Formāts: PDF+DRM
  • Sērija : Chinese Peptide Symposia
  • Izdošanas datums: 11-Apr-2006
  • Izdevniecība: Springer
  • Valoda: eng
  • ISBN-13: 9780306468803
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The Fifth Chinese Peptide Symposium, hosted by Lanzhou University, was held at Lanzhou, China July 14-17, 1998, with 156 participants, including 30 scientists from abroad, representing nine countries. The four-day conference was both intense and spiritually rewarding. Our goal for CPS-98 was to provide a forum for the exchange of knowledge, cooperation and friendship between the international and Chinese scientific communities, and we believe this goal was met. The symposium consisted of 8 sessions with 42 oral and 90 poster presentations, including synthetic methods, molecular diversity and peptide libraries, structure and conformation of peptides and proteins, bioactive peptides, peptide immunology, De Novo design and synthesis of proteins and peptides, ligand-receptor interactions, the chemistry-biology-interface and challenging problems in peptides. The enthusiastic cooperation and excellent contributions were gratifying and the active response of the invited speakers contributed to the success of the symposium. The presentations were of excellent caliber and represented the most current and significant aspects of peptide science. Dr. Kit Lam of the University of Arizona and Dr. Yun-Hua Ye of Peking University were the recipients of The Cathay Award sponsored by the H. H. Liu Education Foundation, offered for their seminal contribution in peptide science and the Chinese Peptide Symposium. Four outstanding young scientists were selected by the organizing committee to receive awards sponsored by Haikou Nanhai Pharmaceutical Industry Co. Ltd. (Zhong He Group).
Preface v Chinese Peptide Symposium -- 1998 vii Session A: Novel approach on synthetic method Orthogonal ligation of free peptides 3(5) J.P. Tam Y.--A. Lu Q. Yu Solid phase synthesis of peptide aldehydes 8(6) J.-A. Fehrentz M. Paris A. Heitz M. Rolland J. Martinez Investigation of enzyme activity and inhibition in the interior of novel solid supports 14(7) M. Meldal P.M. St. Hilaire M. Willert J. Rademann M. Grotli J. Buchardt C.h. Gotfredsen M.A. Juliano L. Juliano K. Bock Immobilization of α-chymotrypsin on zeolite for peptide synthesis in organic solvent 21(5) Y.-H. Ye G.-W. Xing G. -L. Tian C. -X. Li Preparation of a peptide thioester using a fluoren-9-ylmethoxycarbonyl solid-phase method 26(4) X.-Q. Li T. Kawakami S. Aimoto Application of DEPBT for the synthesis of N-protected peptide alcohols 30(3) G. -L. Tian B. -Y. Sun W. Wang Y. -H. Ye Decomposition of amino acid cupric complex by using tetrahydrothiazole-2-thione for preparation of Nα-Boc-Nε-Fmoc-L-Lysine 33(3) X. -M. Gao Y. -H. Ye G. -L. Tian D. Wang Two-step selective formation of three disulfide bridges in the synthesis of δ-Conotoxin P VIA 36(7) H. Jiang C. -X. Fan Z. -W. Miao K. -H. Wei D. -Y. Li M. -N. Zhong J. -S. Chen Session B: Structure, folding and conformation analysis/ De novo design of peptide & protein Design, synthesis and NMR structure of a rigid cyclic peptide template 43(5) S.A. Muhle J.P. Tam Automated docking of Sch68631 with HCV NS3 protease 48(3) X. -J. Xu T. -J. Hou L. -R. Chen Z. Li J. -Q. Wang Molecular modeling of the three-dimensional structure of the human interleukin-11 51(4) L. -R. Chen T. -J Hou X. -J. Xu Z. Li J. -Q. Wang Designing β-hairpin forming short peptide 55(4) Y. -L. Sha Y. -L. Huang Q. Wang L. -H. Lai Anti-tumor activities of papavor somniferum pollen peptides 59(3) J. -X. Xu S. Jin Structural investigation of two pollen peptides by 2 D homonuclear NMR spectroscopy 62(3) Y. -L. Song J. -F. Wang E. -C. Li Z. -C. Qu A comparison of three heuristic algorithms for molecular docking 65(4) T. -J. Hou X. -J. Xu L. -R. Chen Aggregation of a calmodulin-binding peptide 69(6) H. -S. Yan X. -H. Cheng A. -G. Ni B. -L. He Session C: Neuro/Endocrino/Bioactive peptide Neuropeptide AVP(4-8) playing an indirect neurotrophic role 75(2) Q. -W. Yan X. -G. Zhen T. -X. Wang Y. -C. Du Potent bradykinin antagonists having medical potential 77(4) J. M. Stewart L. Gera E. J. York D. C. Chan Understanding the chemistry and biology of rodent relaxin: Role of the C-peptide 81(5) J. D. Wade N. F. Dawson M. Macris M. Mathieu Y. -Y. Tan R. J. Summers G. W. Tregear Purification and characterization of a new conotoxin from the venom of Conus betulinu 86(3) C. -X. Fan M. -N. Zhong H. Jiang S. -Y. Liu D. -Y. Li M. Liu S. -L. Zhang F. -S. Lin J. -S. Chen Synthesis and biological activity of human calcitonin analogs 89(3) C. Yu D. -F. Cui G. -M. Zhou B. -L. Li X. -F. Wu Enhanced expression of CNDF mRNA in rat brain by administration of AVP(4-8) 92(3) W. -X Li B. -X Gu Y. -C Du The synthesis and opioid activities of nociceptin and its fragments 95(3) S. -L. Dong R. Wang T. Wang X. -Y. Hu The effect of Glu position change on the opioid activity of deltorphin II 98(4) R. Wang D. -J. Yang Y. -P. Ma X. -F. Huo J. -M. Shen X. -Y. Hu Isolation and purification of a series of peptides from Panax notoginseng 102(2) J. -G. Ji Y. -H. Ye Y. -W. Zhou Q. -Y. Xing Study of the relationship between structure and function of HIV-1 gp 41 N terminus fusion peptide 104(4) M. Wu S. -Q. Nie Y. Qiu K. -C. Lin S. -X. Wang S. -F. Sui Hypotensive activities of nociceptin and its fragments 108(4) R. Wang T. Wang S. -L. Dong Q. Chen X. -Y. Hu The design and synthesis of endomorphins and their analogues 112(4) X. -F. Huo W. -H. Ren N. Wu R. Wang Neuronal apoptosis induced by β-amyloid peptides in vitro 116(3) W. -X. Li B. -X. Gu Y. -C. Du Studies on the spin-labeling technique on deltrophin II and its analogues 119(5) D. -J. Yang R. Wang Y. -P. Ma Y. -J. Di J. -M. Shen X. -Y. Hu Design and synthesis of salmon calcitonin and its analogues 124(2) H. -P. Pan L. -Y. Wang Z. -Y. Chen F. Wang H. -X. Wang Studies on the synthesis and antithrombosis activity of two peptides derived from the molecular-binding site of fibrinogen 126(3) X. -Y. Hu K. -Q. Li G. -L. Yang C. -H. Li Synthesis and expression of ω-conotoxin MVIIA 129(8) M. -Y. Cai X. -M. Qu Session D: Peptide vaccines/Immunology/Virus Studies on the synthetic peptide vaccines against schistosomiasis 137(3) S. -L. Cao Z. -H. Qin M -S. Cai Y. -E. Shi Studies on the anti-schistosomal synthetic peptide vaccine: Prediction and synthesis of antigenic peptides of Schistosoma paramyosin 140(2) J. -X. Xu J. -H. Yang Construction and expression of a recombinant antibody targeted plasminogen activator 142(3) J. -S. Yang P. -C. Jiang B. -G. Ru Chemical conjugation between haemophilus influenzae type b (hib) polysaccharide and proteins 145(2) P. -S. Lei G. -S. Lu Synthesis of human inhibin fragments, preparation and generation of monoclonal antibodies against human inhibin 147(6) G. -S. Lu Y. Sun P. -S. Lei X. Huang H. -M. Xia X. -D. Gao Session E: Peptide diversity; Chemical libraries; Ligand-receptor interaction; Peptides in therapeutics & diagnosis Design of a δ opioid peptide mimetic based on a topographically constained cyclic enkpehalin 153(5) V. J. Hruby S. Liao M. Shenderovich J. Alfaro-Lopez P. Davis K. Hosohata F. Porreca H.I. Yamamura Tetrazole cis-amide bond mimetics identify the B-turn conformation of insect kinin neuropeptides 158(5) R. J. Nachman J. Zabrocki V. A. Roberts G. M. Coast Synthetic studies of farnesyl protein transferase inhibitor pepticinnamin E 163(3) J. -G. Deng D. -Q. Sun X. -Q. Lin A. -Q. Mi Y. -Z. Jiang Novel coupling reagents 166(3) P. Li J. -C. Xu Pharmacophore model of growth hormone secretagogues 169(3) L. Liu R. -X. Wang L. -H. Lai C. -X. Li Discovery that deltorphin II derivatives are potent melanotropins, putatively active at the Xenopus melanocortin-1 receptor 172(5) V. J. Hruby G. Han M.J. Quillan W. Sadee S. Sharma Session F: Glyco/Lipo/Phospho peptide; peptide diversity/Chemical libraries; Receptor-ligand interaction Enzymatic synthesis of phosphopeptides 177(3) Y. -M. Li Y. -F. Zhao H. Waldmann Synthesis of phosphorylated polypeptide by a thioester method 180(6) S. Aimoto K. Hasegawa X. -Q. Li T. Kawakami Difference between N-phospho-L- and D-Methionine in ester exchange reaction with uridine 186(2) Y. Ma G. -F. Shi Y. -P. Feng Y. -F. Zhao Synthesis of analogs of phosphoamino acids and their biomimic reactions 188(4) Y. Ju D. -Y. Qin Y. -F. Zhao Solid phase synthesis of heterocyclic combinatorial libraries derived from peptides 192(6) J. M. Ostresh C. C. Schoner V. T. Hamashin M. Giulianotti A. Nefzi M. J. Kurth R. A. Houghten Parallel synthesis of muramyl peptides derivatives 198(4) S. -D. Zhang G. Liu S. -Q. Xia Z. -K. Ding β-Cyclodextrin for presentation of bioactive peptides to molecular recognition 202(8) N. Schaschke S. Fiori H. -J. Musiol I. Assfalg-Machleidt W. Machleidt C. Escrieut D. Fourmy G. Muller L. Moroder The C-terminus of δ-opioid receptor does not control DPDPE-induced desensitization 210(5) D. -H. Zhou C. -H. Wang Q. Wei G. Pei Z. -Q. Chi Session G: Peptides in therapeutics and diagnosis Detection of gene expression product of transgenic tobacco by antigenic peptide 215(2) J. -X. Xu Y. Ma M. Ma X. -P. Lin Advantages of Calcitonin complexed with SA liposome 217(4) D. Wang C. Yu H. -X. Xuan D. -F. Cui Q. -S. Lin Hypoglycemic effects of insulin sublingual drops containing azone on rats and rabbits 221(6) H. Peng Q. -H. Gao Q. Chen Y. -S. Zhu K. -X. Huang Session H: Other research related to peptides and proteins Secretory expression of porcine insulin precursor in methylotrophic yeast Pichia pastoris 227(3) Y. Wang Z. -H. Liang Y. -M. Fent Y. -S. Zhang Chemo-enzymatic syntheses of eel calcitonin analogs having natural N-linked oligosaccharides 230(4) T. Inazu M. Mizuno I. Muramoto K. Haneda T. Kawakami S. Aimoto K. Yamamoto Design of specific inhibitors at the ATP binding site of DNA topoisomerases II 234(4) L. Assairi Applications of optical biosensors to structure-function studies in the EGF/EGF receptor system 238(6) E.C. Nice T. Domagala F. Smyth N. Konstantopoulos M. Nerrie D. Geleick B. Catimel A. W. Burgess Experimental study of osteogenic growth peptide promoting bone mass in rat osteoporosis 244(3) D. -Y. Shi C. Yu T.-Y. Chen M.-Y. Li D.-F. Cui Z.-W. Chen Determination of inhibitory constants for CPA by competitive spectrophotometry 247(2) N. -J. Hong J. -W. Lee S. -H. Chang D. H. Jin Sublingual administration of monomeric insulin --destetrapeptide insulin 249(3) M. -Y. Li H. Peng M. -R. Ai H. -B. Xu Y. -X. Zhang How to get patent rights to protect your invention in biotechnology 252(3) L. Zhou Study of peptide maps from milk protein hydrolysates by SE-HPLC 255(3) L. Zhao Y. Q. Li Z. -L. Chen S. -W. She Y. -F. Wang Synthesis and solution structures of new chiral enantiomeric peptide nucleic acid (PNA) dimers 258(4) L. -G. Zhang J. -M. Min L. -H. Zhang Study of one type of metallothionein and SZ51 recombinant protein directing and imaging reagent 262(2) Y. Sun B. -G. Ru LHRH antagonists: new preclinical and clinical results 264(5) B. Kutscher M. Bernd W. Deger T. Reissmann R. Deghengi J. Engel DNA-binding characteristic of the antitumor drug actinomycin D and its analogs 269(5) J. -H. Shen X. -W. Yang Z. -P Jia R. Wang Design and synthesis of the peptide analogs of antitumor agent actinomycin D 274(5) X. -W. Yang J. -H. Shen Z. -P. Jia R. Wang Author index 279(4) Subject index 283