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E-grāmata: Personalized Anaesthesia: Targeting Physiological Systems for Optimal Effect

  • Formāts: EPUB+DRM
  • Izdošanas datums: 06-Feb-2020
  • Izdevniecība: Cambridge University Press
  • Valoda: eng
  • ISBN-13: 9781108775816
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  • Formāts: EPUB+DRM
  • Izdošanas datums: 06-Feb-2020
  • Izdevniecība: Cambridge University Press
  • Valoda: eng
  • ISBN-13: 9781108775816
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Personalized Anaesthesia presents a modern vision of anaesthesia. Integrating technology and knowledge from leading experts in the field, this book will change the way anaesthesia is both taught and practiced. Modern practice requires the anaesthetist to provide patient-specific management. This is the first resource to be organised by the desired physiological effect, rather than by drug groupings, explaining how physiological changes can be produced and controlled according to the characteristics of each patient and the particular surgical context. The book integrates physiology, pharmacology and technology, and applies these concepts in a systematic manner to each homeostatic system. This will optimise drug titration, effect quantification and decision making in anaesthesia practice to match the needs of the individual patient. Complex mathematical and scientific concepts are explained using accessible text, colour illustrations throughout and graphs. This is an essential text for any consultant or trainee working in anaesthesia.

Modern anaesthetic practice requires patient-specific management. This book explains how physiological changes can be produced and controlled according to the characteristics of each patient and the surgical context. Complex mathematical and scientific concepts are explained using accessible didactic text, colour illustrations, and graphs.

Papildus informācija

Presents a modern vision of anaesthesia, integrating technology and knowledge, to change how anaesthesia is taught and practised.
List of Contributors
vi
Foreword ix
Introduction xii
Section 1 Basic Principles
1 Principles of Quantitative Clinical Pharmacology
1(13)
Pedro L. Gambiis
Sebastian Jaramillo
2 Pharmacokinetic and Pharmacodynamic Modelling in Anaesthesia
14(15)
Maria J. Garrido
Inaki F. Troconiz
3 Drug Interactions: Additivity and Synergy among Anaesthetic Drugs
29(11)
Jacqueline A. Hannam
Timothy G. Short
4 Covariate Analysis in Clinical Anaesthesia
40(23)
Luis I. Cortinez
Brian J. Anderson
5 Signal Analysis and Response Measurement
63(19)
Umberto Melia
Erik W. Jensen
Jose F. Valencia
6 Application of Pharmacokinetics and Pharmacodynamics and Signal Analysis to Drug Administration in Anaesthesia
82(21)
R. Ross Kennedy
Section 2 Targeting Effects
7 Hypnotic Effect: Inducing Unconsciousness and Emergence from Anaesthesia
103(14)
Sergio Vide
Catarina Nunes
Pedro Amorim
8 Analgesia: Effects on Response to Nociceptive Stimulation
117(11)
Emmanuel Boselli
Mathieu Jeanne
9 Personalized Sedation and Analgesia
128(18)
Michael M. Beck
Jeffrey B. Horn
Ken B. Johnson
10 Respiratory Depression
146(11)
Malin Jonsson Fagerlund
11 Immobility
157(18)
Klaus T. Olkkola
Douglas J. Eleveld
12 Effects on Brain Function
175(22)
Neus Fabregas
Adrian W. Gelb
13 Targeted and Individualized Perioperative Medicine for Cognitive Dysfunction
197(9)
Pauline Glasman
Alice Jacquens
Vincent Degos
14 Cardiac and Haemodynamic Function
206(16)
Kai Kuck
Natalie Silverton
Michael K. Cahalan
15 Effects of Anaesthesia on Thermoregulation
222(16)
Oliver Kimberger
16 Effects of Perioperative Management on Kidney Function
238(7)
Xavier Borrat
Jordi Mercadal
17 Effects on Liver Function
245(12)
Andre M. De Wolf
Jan F. A. Hendrickx
18 Effects on Fluid Balance
257(14)
Robert G. Hahn
19 Ventilation during General Anaesthesia
271(14)
Lluis Gallart
20 Epilogue: Artificial Intelligence Methods
285
Sebastian Jaramillo
Jose F. Valencia
Pedro L. Gambiis
Pedro Gambus is a consultant anaesthetist at the Hospital CLINIC de Barcelona and Associate Professor of Biomedical Engineering at the Universitat de Barcelona, former postdoctoral fellow at the Department of Anesthesia at Stanford University, California, and Visiting Professor at the Department of Anesthesia and Perioperative Care University of California in San Francisco (UCSF). Jan Hendrickx is a consultant anaesthetist at Aalst General Hospital and Adjunct Professor at the Department of Anesthesia at Stanford University, California.