This book presents the best practice, indications and drugs most used in the practice of noninvasive ventilation (NIV). In the last two decades NIV has made a lot of progress in different scenarios and etiologies of respiratory failure. The treatment of these patients frequently involves the use of drugs to control patient's symptoms such as dyspnea, discomfort and some of them can have direct or indirect effects on lung function. The volume is organized into various sections - dedicated both to adults as well as pediatrics - where the most frequent clinical conditions requiring for the use of a pharmacological support are described. Furthermore, this book is conceived as a quick reference guide including an analysis of the indications of drugs dosage and the pharmacological interactions that can be observed in lung function in patients undergoing NIV.
Thanks to its contents, readers can quickly consult indications, contraindications, doses, the most suitable treatments to achieve the maximum NIV as well as the most important side effects reported by clinicians.
In this book specialists in critical care and pharmacology, managing both adult and pediatric population, shed a light to the proper medication management and best drugs choice in patients with indications for NIV
Noninvasive mechanical ventilation - Pharmacology-basic relationship.-
Part I. Pharmacological Clinical Indications in Adults.- Airway diseases.-
Sedation.- Analgesics.- Antinflammatory drugs.- Cardiovascular drugs.-
Antibiotics drugs.- Sleep Medicine drugs.- Psychiatric drugs.- Procedures.-
Part II. Monitoring and Complications Pharmacology in Noninvasive Mechanical
Ventilation.- Monitoring practical options.- Complications.- Part III.
Pharmacological Clinical Indications in Pediatric Patients.- Aerosol Therapy
(bronchodilators, corticoids), Surfactant Therapy,
Humidification. Heliox/Nitric Oxygen.- Sedo analgesia.- Aerosol Therapy.
Benzodiazepines, Dexmedetomidine, Ketamine, Opiates.- Aerosol Therapy.
Anti-inflammatory drugs.- Antihypertensive drugs for pulmonary hypertension,
Cardiovascular drugs for right and left Ventricular failure.- Neurologic
drugs (anti-epileptic, anti-dystonic).- Dyspnoea, Patient-Ventilator
Asynchrony, Sleep Disorder, Specific Infection-Highrisk viral, Cardiac
pulmonary Edema, Chronic Heart failure.- Adaptation-Intolerance, Delirium in
Agitated patients, Neuromuscular disorders Breathing and swallowing,
Convulsive therapy.- Procedures.- Part IV. Special Section-ePocket Guide For
Drugs Dose Clinical Practical Approach in Special NIV Indications.-
Persistent-Dyspnoea.- Discomfort-Adaptation-Intolerance Patient-ventilator
asynchrony.- Cardiac pulmonary edema.- Politraumatized patients.-
Preoxygenation Adjunct to extubation-noninvasive mechanical ventilation.-
Chronic obstructive pulmonary disease.- Neuromuscular disorders.
Prof. Antonio M. Esquinas, MD, PhD, FCCP, FNIV, International fellow of the American Association for Respiratory Care (AARC), is a critical care specialist and staff physician at the Intensive Care Unit at the Hospital Morales Meseguer, Murcia, Spain. He is the Director of the International School of Non-Invasive Mechanical Ventilation, International College of Experts in Non Invasive Ventilation, Director, Academy of Non Invasive Ventilation and Director International Non-invasive Ventilation Fellowship Program and President of International Association of Non Invasive Ventilation. His main research activities are related to noninvasive mechanical ventilation in pulmonary and critical care. Prof. Esquinas is the author of more than 670 scientific publications (402 on peer-reviewed journals), editor of 60 books (published in English, Portuguese, Spanish and Chinese) and author of 325 chapters of book/position paper. He was invited speaker at 356 presentations and presented 450 oral communications or posters at national and international congresses. He acts in international networking groups promoting education programs and research in noninvasive ventilation.
Bushra Mina is the Director of the Pulmonary Critical Care Fellowship Program, Chief Pulmonary Medicine and Associate Professor at the Zucker School of Medicine at Hofstra/Northwell Lenox Hill Hospital, USA. Dr. Mina, member of the Lenox Hill GME committee and Northwell GME committee, is also an Advanced Simulation Instructor, contributing to medical residents education and training in diagnosing and treating acute illness through rapid response simulation program. Dr. Mina has a leadership position in the Pulmonary Emboli Response Team (PERT) and COPD Response Team at his institution where a multidisciplinary approach toward treating patients with pulmonary emboli, and COPD is utilized.
His main research interests include noninvasive ventilation, palliative care, thromboembolic disease, and COPD. He also evaluated the use of ultrasound as an educational tool in developing housestaff skills using bedside ultrasonograpy and echocardiography.
Involved in several educational committees in national societies involving activities involving patient and residents mentoring and education in pulmonary emboli, COPD, and disaster managements, Dr. Mina is author of papers published by international peer review journals as well as authors of 16 book chapters.
Savino Spadaro is Associate Professor in Anesthesia and Intensive Care University of Ferrara, Department of Translational medicine and staff member in Anesthesia and Intensive care department at SantAnna Hospital of Ferrara. In 2015 he was visiting fellow at Imperial College Saint Marys Hospital in London. He is an Associate editor of BMC pulmonary medicine and senior editor of BMC anesthesiology and member of several international Societies such as the European Society of Intensive Medicine, European Respiratory Society, European Society of Anesthesiology, Societa Italiana di Anestesia Analgesia Rianimazione terapia del dolore, Member of the PLUG working group.
Prof. Spadaros fields of interest are the respiratory monitoring in mechanically ventilated patients, diaphragmatic dysfunction in critically ill patients, markers of respiratory muscles damage during mechanical ventilation, the role of assisted mechanical ventilation on respiratory muscle activity and weaning from mechanical ventilation. He is author of original peer reviewed papers published on international scientific journals and also book chapters author. His activity is also completed by a teaching activity at the
School of Medicine of University of Ferrara of courses in: Emergency and Critical Care, Emergency and Anesthesia, Nutrition in critically ill patients.
Daniela Perrotta is responsible for the UOC Palidoro at Ospedale BambinGesł of Rome. She obtained a specialization in Anesthesia and Resuscitation (Universitą Cattolica del Sacro Cuore, Rome), in Aeronautic and Space Medicine (Universitą degli Studi La Sapienza, Rome) and a Master in Pediatric Pneumology (Universitą degli Studi La Sapienza, Rome). Dr. Perrotta is also an academic teacher of: physiopathology and general pathology at the nursing course (Tor Vergata University, Rome), course on resuscitation of the newborn in the delivery room (European School of Obstetric Anesthesiology, Rome), lecturer at two-year master's degree in fetus and newborn module (European School of Obstetric Anesthesiology, Rome). She is also instructor of Pediatric Advanced Life Support, CRM simulator instructor (InPass Institut GmbH, Germany) and AHA full instructor.
Dr. Perrotta published on international scientific journals and she is a member of international scientific Societies such as ESPNIC, AAROI, SIMEUP, SARNEPI.
Francesco De Sanctis obtained his Medical Degree at University La Sapienza, SantAndrea Hospital, Rome. He is a pediatric anesthesiologist and pediatric intensivist at Bambino Gesł Children Hospital, Palidoro, Rome. He is author of scientific publications and attended several training and professional developmental courses.
Dr. De Sanctis is passionate about ultrasound and ventilation in the pediatric field. In recent years he studied ultrasound analysis of respiratory system, he has deepened methods of invasive and non-invasive ventilatory support and of weaning from mechanical ventilator. Dr. De Sanctis participated in several editions of ESPNIC and SARNePI congresses, as speaker, presenting clinical cases.
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