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Phytochemistry of Plants of Genus Ocimum [Hardback]

, , (Central Drug Research, India),
  • Formāts: Hardback, 82 pages, height x width: 216x138 mm, weight: 235 g, 8 Tables, black and white; 14 Illustrations, black and white
  • Sērija : Phytochemical Investigations of Medicinal Plants
  • Izdošanas datums: 29-Jun-2020
  • Izdevniecība: CRC Press
  • ISBN-10: 0367857537
  • ISBN-13: 9780367857530
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Phytochemistry of Plants of Genus OcimumPalielināt
  • Formāts: Hardback, 82 pages, height x width: 216x138 mm, weight: 235 g, 8 Tables, black and white; 14 Illustrations, black and white
  • Sērija : Phytochemical Investigations of Medicinal Plants
  • Izdošanas datums: 29-Jun-2020
  • Izdevniecība: CRC Press
  • ISBN-10: 0367857537
  • ISBN-13: 9780367857530
Citas grāmatas par šo tēmu:
Permanent link: https://www.kriso.lv/db/9780367857530.html
Keywords:
Ocimum species has been used as a traditional remedy for various ailments such as arthritis, bronchitis, cold, conjunctivitis, diarrhea, dysentery, and flatulence, as well as for healing wounds and lowering blood glucose level. These are characterized by variations in their morphology such as the shape, size and pigmentation of leaves, which cause differences in chemical composition and affect the commercial value of this genus. This book describes phytochemical investigations of Ocimum species using LC-MS/MS instruments to study qualitative and quantitative variations of phytochemicals in different Ocimum species.

Features:











Collection of Ayurvedic features and scientific analytical and pharmacological evidence of most important medicinal plants of genus Ocimum.







Chemical signatures for the identification of Ocimum species.





Easy-to-use analytical procedure for quality control of plants of Ocimum species and its herbal products.
Preface vii
Acknowledgments ix
Authors xi
List of Abbreviations and Units
xiii
1 Introduction
1(18)
1.1 Worldwide Distribution of Genus Ocimum
1(3)
1.2 Introduction: Selected Ocimum Species
4(1)
1.3 Botanical Description of Selected Ocimum Species
4(4)
1.3.1 O. americanum L.
4(1)
1.3.2 O. basilicum L.
5(1)
1.3.3 O. gratissimum L.
6(1)
1.3.4 O. kilimandscharicum Gurke
7(1)
1.3.5 O. tenuiflorum L.
7(1)
1.4 Phytochemistry of Selected Ocimum Species
8(3)
1.5 Pharmacological Activity of Selected Ocimum Species
11(8)
2 Rapid Screening of Phytochemicals in Ocimum Species
19(24)
2.1 Plant Material
19(1)
2.2 Instrumentation and Analytical Conditions
19(1)
2.2.1 HPLC-QTOF-MS/MS Conditions
19(1)
2.3 HPLC-QTOF-MS/MS Analysis
20(15)
2.4 Identification of Flavonoids
35(1)
2.5 Flavonoid C-Glycosides
35(3)
2.6 Flavones and Their O-Glycosides
38(1)
2.7 Flavonols and Their O-Glycosides
39(1)
2.8 Identification of Propenyl Phenol Derivatives
40(1)
2.9 Identification of Triterpenic Acids
40(1)
2.10 Identification of Phenolic Acids and Their Esters
41(2)
3 Quantitation of Bioactive Phytochemicals in Ocimum Species and Its Marketed Herbal Formulations Using UHPLC-MS
43(20)
3.1 Plant Extracts and Marketed Formulations
44(1)
3.2 Instrumentation and Analytical Conditions for Quantitation of 15 Analyte in Six Ocimum Species
45(1)
3.2.1 UHPLC-QqQLIT-MS/MS Conditions
45(1)
3.3 Optimization of UHPLC-QqQUT-MS/MS Conditions for Quantitative Analysis of 15 Analytes in Six Ocimum Species
46(1)
3.4 Analytical Method Validation for Quantitative Analysis of 15 Analytes in Six Ocimum Species
47(1)
3.4.1 Linearity, LOD and LOQ
47(1)
3.4.2 Precision, Stability and Recovery
48(1)
3.5 Quantitative Analysis of 15 Analytes in Six Ocimum Species Samples
48(3)
3.6 Instrumentation and Analytical Conditions for Quantitation of 23 Analyte in Geographical Samples of O. sanctum and Their Herbal Formulations
51(2)
3.6.1 UHPLC Conditions
51(1)
3.6.2 MS Conditions
52(1)
3.7 Optimization of UHPLC-QqQLIT-MS/MS Conditions for Quantitative Analysis of 23 Analytes in O. sanctum Sample and Their Herbal Formulations
53(2)
3.8 Analytical Method Validation for Quantitative Analysis of 23 Analytes in O. sanctum Sample and Their Herbal Formulations
55(1)
3.8.1 Linearity, LOD and LOQ
55(1)
3.8.2 Precision, Stability and Recovery
56(1)
3.9 Quantitative Analysis of 23 Analytes in O. sanctum Sample and Their Herbal Formulations
56(4)
3.10 Discrimination of O. sanctum from Different Geographical Regions by PCA
60(3)
4 Conclusion
63(2)
References 65(12)
Index 77
Dr. Brijesh Kumar is a Professor (AcSIR) and Chief Scientist of sophisticated analytical instrument facility division, CSIR-Central Drug Research Institute Lucknow. India. He has completed his PhD from CSIR-CDRI Lucknow (Dr. RML Avadh University Faizabad UP, India). Currently he is facility in charge at Sophisticated Analytical Instrument Facility (SAIF) division of CSIR-CDRI. He has to his credit more than 7 book chapters, three book and 145 papers in International journal of repute. His current area of research is applications of Mass Spectrometry tools (DART MS/Q-TOF LC-MS/4000 Q Trap LC-MS/ Orbitrap MSn) for qualitative and quantitative analysis molecules for quality control and authentication/standardization of Indian medicinal plants/parts and their herbal formulations. He is also involved in identification of marker compounds using statistical software to check adulteration/substitution.

Vikas Bajpai completed his PhD from the Academy of Scientific and Innovative Research (AcSIR), New Delhi, India and carried his research work under supervision of Dr. Brijesh Kumar at CSIR-Central Drug research Institute Lucknow. His research includes development and validation of LC-MS/MS methods for qualitative and quantitative analysis of small molecules, Indian medicinal plants and phytochemicals.

Ms. Surabhi Tiwari completed her masters from the University of Allahabad India in Chemistry. She has worked in Pharmacognosy Division, NBRI, Lucknow, for analysis of herbals using instruments like- HPTLC and HPLC. Currently she is working as Senior Research Fellow in SAIF Division under supervision of Dr. Brijesh Kumar at CSIR-Central Drug research Institute Lucknow India. Her current research interest includes phytochemical analysis of medicinal plants.