Atjaunināt sīkdatņu piekrišanu

E-grāmata: Plasmid Biopharmaceuticals - Basics, Applications, and Manufacturing: Basics, Applications, and Manufacturing [Wiley Online]

  • Formāts: 616 pages
  • Izdošanas datums: 26-Aug-2011
  • Izdevniecība: John Wiley & Sons Inc
  • ISBN-10: 470939915
  • ISBN-13: 9780470939918
Citas grāmatas par šo tēmu:
  • Wiley Online
  • Cena: 174,12 €*
  • * this price gives unlimited concurrent access for unlimited time
  • Formāts: 616 pages
  • Izdošanas datums: 26-Aug-2011
  • Izdevniecība: John Wiley & Sons Inc
  • ISBN-10: 470939915
  • ISBN-13: 9780470939918
Citas grāmatas par šo tēmu:
The book addresses the basics, applications, and manufacturing of plasmid biopharmaceuticals. The survey of the most relevant characteristics of plasmids provides the basics for designing plasmid products (applications) and processes (manufacturing). Key features that the authors include in the book are: i) consistency and clear line of direction, ii) an extensive use of cross-referencing between the individual chapters, iii) a rational integration of chapters, iv) appellative figures, tables and schemes, and v) an updated, but selected choice of references, with a focus on key papers.
Preface ix
Acknowledgment xiii
Abbreviations xv
Part I Basics
1 Historical Perspective
3(32)
2 Gene Transfer with Plasmid Biopharmaceuticals
35(34)
3 Product and Process Development
69(16)
4 Structure
85(44)
5 Analytical Characterization
129(38)
6 Delivery
167(46)
Part II Applications
7 Ethical and Safety Issues
213(30)
8 Human and Veterinary Markets
243(30)
9 Human Case Studies: Pandemic Influenza and Critical Limb Ischemia
273(28)
10 Veterinary Case Studies: West Nile, Infectious Hematopoietic Necrosis, and Melanoma
301(28)
Part III Manufacturing
11 Good Manufacturing Practice and Validation
329(28)
12 Product Specifications and Quality Control
357(34)
13 Cell Culture
391(24)
14 An Overview of Downstream Processing
415(12)
15 Primary Isolation
427(28)
16 Intermediate Recovery
455(42)
17 Final Purification
497(46)
18 Process Synthesis
543(22)
Part IV Concluding Remarks and Outlook
19 Concluding Remarks and Outlook
565(14)
Index 579
Duarte Miguel F. Prazeres, PhD, DSc, is Associate Professor at the Instituto Superior Técnico (IST) and Senior Researcher at the Instituto de Biotecnologia e Bioengenharia, both within the Universidade Técnica de Lisboa. Dr. Prazeres has published 140 peer-reviewed articles and fifteen book chapters on such topics as biocatalysis, downstream processing, and nanobiotechnology.