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E-grāmata: Positron Emission Tomography: Methods and Protocols

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  • Formāts: PDF+DRM
  • Sērija : Methods in Molecular Biology 2729
  • Izdošanas datums: 25-Nov-2023
  • Izdevniecība: Springer-Verlag New York Inc.
  • Valoda: eng
  • ISBN-13: 9781071634998
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Positron Emission Tomography: Methods and ProtocolsPalielināt
  • Formāts: PDF+DRM
  • Sērija : Methods in Molecular Biology 2729
  • Izdošanas datums: 25-Nov-2023
  • Izdevniecība: Springer-Verlag New York Inc.
  • Valoda: eng
  • ISBN-13: 9781071634998
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This detailed volume explores key concepts and experimental design related to Positron Emission Tomography (PET) imaging that have revolutionized our understanding of human biology. The first part focuses on recent advances in radiotracer probe development to enable the detection of materials, from large macromolecules to complicated drug-like structures. The next section describes how key physiological and pathophysiological processes can be interrogated and quantifiably measured with this imaging technique. Finally, chapters examine important technological developments in the field that are revolutionizing the way these innovative PET probes are utilized in the clinic. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. 

Authoritative and practical, Positron Emission Tomography: Methods and Protocols serves as an ideal guide for researchers looking to use imaging to revolutionize the way we diagnose and treat disease.

Recenzijas

This book is a must-have in all PET research settings, where professionals from a multitude of areas will benefit from the detail of the description of the protocols, as well as the insight provided by the contextual materials included. (André Nunes, RAD Magazine, May, 2024)

11C-Fixation Techniques.- Enantioselective Synthesis of Carbon-11
Labeled Amino Acids and Peptides.- Silicon Fluoride Acceptors (SiFA) for
18F-Radiolabeling: From Bench to Bedside.- Tandem Iridium-Catalyzed C-H
Borylation/Copper-Mediated Radiofluorination of Aromatic C-H Bonds with
[ 18F]TBAF.- Preparation of [ 68Ga]GaCl3 Using a Cyclotron.- Transition and
Post-Transition Radiometals for PET Imaging and Radiotherapy.- Rapid
Radiolabeling for Peptide Radiotracers.- Methods for the Production of
Radiolabeled Bioagents for ImmunoPET.- Radiolabeled Antibodies for Immune
Checkpoint PET in Preclinical Research.- Radiolabeled Affibody Molecules for
PET Imaging.- Small Animal Multisubject PET/CT Workflow.- The Basics of
Visualizing, Analyzing, and Reporting Preclinical PET/CT Imaging Data.-
Radiosynthesis of [ 18F]FPenM-C2Am: A PET Imaging Agent for Detecting Cell
Death.- Imaging the Tumor Antioxidant Response with [ 18F]FSPG PET.-
Characterization and Validation of Radiotracer Kinetics Using the Langendorff
Isolated Perfused Heart.- Brain PET Imaging in Small Animals: Tracer
Formulation, Data Acquisition, Image Reconstruction, and Data Analysis.-
CRISPR/Cas for PET Reporter Gene Engineering.- Genetic Engineering of
Therapeutic Cells with the Sodium Iodide Symporter (NIS) to Enable
Non-Invasive In Vivo Therapy Tracking.- Single-Cell PET Imaging and
Tracking.- PET System Technology: Theoretical Aspects and Experimental
Methodology.- Practical Considerations for Total-Body PET Acquisition and
Imaging.- Combined PET/MR: Where Anatomical Imaging Meets Cellular Function.-
Quantitation of Oncologic Image Features for Radiomic Analyses in PET.-
Multiplexing Autoradiography.- Kinetic Modeling Methods in Preclinical
Positron Emission Tomography Imaging.
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