List of Contributors |
|
ix | |
Preface |
|
xv | |
|
1 Introduction: Two Centuries of Progress in Transfusion Medicine |
|
|
1 | (10) |
|
|
Part I Basic Principles of Immunohaematology |
|
11 | (58) |
|
2 Essential Immunology for Transfusion Medicine |
|
|
11 | (9) |
|
|
|
3 Human Blood Group Systems |
|
|
20 | (9) |
|
|
4 Human Leucocyte Antigens |
|
|
29 | (14) |
|
|
|
5 Platelet and Neutrophil Antigens |
|
|
43 | (15) |
|
|
6 Pretransfusion Testing and the Selection of Red Cell Products for Transfusion |
|
|
58 | (11) |
|
|
Part II Complications of Transfusions |
|
69 | (115) |
|
7 Investigation of Acute Transfusion Reactions |
|
|
69 | (12) |
|
|
|
8 Haemolytic Transfusion Reactions |
|
|
81 | (16) |
|
|
|
|
9 Febrile and Allergic Transfusion Reactions |
|
|
97 | (11) |
|
|
|
10 Lung Injury and Pulmonary Oedema After Transfusion |
|
|
108 | (10) |
|
|
|
11 Purported Adverse Effects of 'Old Blood' |
|
|
118 | (7) |
|
|
|
12 Transfusion-Induced Immunomodulation |
|
|
125 | (11) |
|
|
|
|
|
13 Transfusion-Associated Graft-Versus-Host Disease and Microchimerism |
|
|
136 | (11) |
|
|
|
|
14 Posttransfusion Purpura |
|
|
147 | (6) |
|
|
15 Transfusion-Transmitted Infections |
|
|
153 | (15) |
|
|
|
16 Bacterial Contamination |
|
|
168 | (8) |
|
|
|
17 Emerging Infections and Transfusion Safety |
|
|
176 | (8) |
|
Part III Practice in Blood Centres and Hospitals |
|
184 | (80) |
|
18 Regulatory Aspects of Blood Transfusion |
|
|
184 | (9) |
|
|
|
|
19 The Role of Haemovigilance in Transfusion Safety |
|
|
193 | (10) |
|
|
|
20 Donors and Blood Collection |
|
|
203 | (12) |
|
|
|
|
21 Blood Donation Testing and the Safety of the Blood Supply |
|
|
215 | (7) |
|
|
22 Production and Storage of Blood Components |
|
|
222 | (11) |
|
|
|
|
|
23 Blood Transfusion in Hospitals |
|
|
233 | (21) |
|
|
|
|
24 Blood Transfusion in a Global Context |
|
|
254 | (10) |
|
|
|
|
|
|
Part IV Clinical Transfusion Practice |
|
264 | (119) |
|
25 Inherited and Acquired Coagulation Disorders |
|
|
264 | (15) |
|
|
|
|
279 | (8) |
|
|
27 Blood Management in Acute Haemorrhage and Critical Care |
|
|
287 | (15) |
|
|
|
|
|
28 Point-of-Care Testing in Transfusion Medicine |
|
|
302 | (10) |
|
|
|
29 Haematological Disease |
|
|
312 | (18) |
|
|
|
|
30 Blood Transfusion in the Management of Patients with Haemoglobinopathies |
|
|
330 | (11) |
|
|
31 Heparin-Induced Thrombocytopenia |
|
|
341 | (16) |
|
|
|
32 Immunodeficiency and Immunoglobulin Therapy |
|
|
357 | (14) |
|
|
33 Transfusing Neonates and Infants |
|
|
371 | (12) |
|
Part V Patient Blood Management |
|
383 | (46) |
|
34 Development of a Patient Blood Management Programme |
|
|
383 | (10) |
|
|
35 Perioperative Patient Blood Management |
|
|
393 | (12) |
|
|
|
|
36 Restrictive Transfusion Practice and How to Implement It |
|
|
405 | (11) |
|
|
|
37 Using Data to Support Patient Blood Management |
|
|
416 | (13) |
|
|
Part VI Cellular and Tissue Therapy and Organ Transplantation |
|
429 | (79) |
|
38 Regulation and Accreditation in Cellular Therapy |
|
|
429 | (13) |
|
Zbigniew M. Szczepiorkowski |
|
|
|
39 Stem Cell Collection and Therapeutic Apheresis |
|
|
442 | (13) |
|
|
Zbigniew M. Szczepiorkowski |
|
|
40 Haemopoietic Stem Cell Processing and Storage |
|
|
455 | (11) |
|
|
|
|
41 Haematopoietic Stem Cell Transplantation |
|
|
466 | (11) |
|
|
|
|
42 Cord Blood Transplantation |
|
|
477 | (13) |
|
|
|
43 Recent Advances in Clinical Cellular Immunotherapy |
|
|
490 | (10) |
|
|
|
|
500 | (8) |
|
|
|
Part VII Development of the Evidence Base for Transfusion |
|
508 | (64) |
|
45 Observational and Interventional Trials in Transfusion Medicine |
|
|
508 | (12) |
|
|
|
|
46 Getting the Most Out of the Evidence for Transfusion Medicine |
|
|
520 | (13) |
|
|
|
|
|
47 A Primer on Biostatistics |
|
|
533 | (16) |
|
|
|
48 A Primer on Health Economics |
|
|
549 | (11) |
|
|
|
49 Scanning the Future of Transfusion Medicine |
|
|
560 | (12) |
|
|
|
Index |
|
572 | |