Acknowledgements |
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v | |
Foreword |
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vii | |
Preface |
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ix | |
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1 The Cardiovascular Examination |
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1 | (6) |
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Case 1 Scenario: Tara With Dyspnoea |
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1 | (1) |
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An Outline of the Cardiovascular Examination |
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1 | (4) |
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Left Ventricular Failure (LVF) |
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5 | (1) |
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Right Ventricular Failure (RVF) |
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6 | (1) |
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2 Common Valvular Heart Disease |
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7 | (14) |
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7 | (1) |
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Case 2 Scenario: Bill With Heart Murmur |
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7 | (3) |
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7 | (1) |
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8 | (1) |
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Indications for Intervention in Aortic Stenosis |
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9 | (1) |
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Long-term Management and Follow-up |
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10 | (1) |
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10 | (1) |
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Case 3 Scenario: Mrs AB With Exertional Dyspnoea |
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11 | (4) |
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11 | (2) |
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13 | (1) |
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Indications for Intervention in Mitral Regurgitation |
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14 | (1) |
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Long-term Management and Follow-up |
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15 | (1) |
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15 | (1) |
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Case 4 Scenario: Mr AL With Mild Exertional Dyspnoea |
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16 | (5) |
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16 | (1) |
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17 | (1) |
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Surgery in Severe Aortic Regurgitation |
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18 | (1) |
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Long-term Management and Follow-Up |
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18 | (3) |
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3 ST Elevation Myocardial Infarction |
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21 | (10) |
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Case 5 Scenario: John With Chest Pain |
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21 | (1) |
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Common Symptoms of Ischaemia |
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21 | (1) |
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Role of Initial ECG and Serial Troponin in Acute Myocardial Infarction |
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21 | (1) |
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21 | (1) |
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22 | (1) |
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Additional Investigations Including CXR and Echocardiography |
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22 | (1) |
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Management Strategies of Acute Myocardial Infarction |
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23 | (3) |
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23 | (1) |
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Common Antiplatelet Drugs |
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23 | (1) |
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Reperfusion: Primary Angioplasty (PTCA) vs Thrombolysis |
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24 | (2) |
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Myocardial Infarction in Australia |
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26 | (1) |
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Definitions of Myocardial Infarction |
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26 | (1) |
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Pathogenesis of Myocardial Infarction |
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26 | (1) |
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Clinical Classification of Myocardial Infarction |
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26 | (5) |
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ECG Diagnostic Criteria of ST Elevation Myocardial Infarction |
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27 | (2) |
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29 | (2) |
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4 Secondary Prevention of Coronary Artery Disease |
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31 | (10) |
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Case 6 Scenario: John in Cardiac Rehab |
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31 | (1) |
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Lifestyle Changes in the Long-term Management of Cardiovascular Disease |
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31 | (1) |
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Effect of Exercise, Smoking and Diet on Cholesterol |
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31 | (1) |
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Pharmacotherapy With Statins in the Treatment of High LDL-C |
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32 | (3) |
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34 | (1) |
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Goals of Lipid Lowering in Patients With Vascular Disease |
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34 | (1) |
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Safety of Statin Treatment |
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34 | (1) |
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Role of Statin in Reducing the Atheroma Volume |
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34 | (1) |
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Efficacy of Different Statins in Prevention of Vascular Disease |
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34 | (1) |
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What are the Roles of Different Antiplatelet Medications? |
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35 | (1) |
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35 | (1) |
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35 | (1) |
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35 | (1) |
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35 | (1) |
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Summary of Dual Antiplatelet Agents |
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36 | (1) |
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Role of Beta-blockers and ACE Inhibitors in Secondary Prevention of Cardiovascular Disease |
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36 | (1) |
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36 | (1) |
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Angiotensin Converting Enzyme (ACE) Inhibitors/Angiotensin Receptor Blockers (ARBs) |
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36 | (1) |
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Management of Coronary Artery Disease in the Presence of Atrial Fibrillation |
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37 | (4) |
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Role of Double Therapy vs Triple Therapy |
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37 | (4) |
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5 Management of Acute Chest Pain |
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41 | (8) |
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Case 7 Scenario: Dawn With Chest Pain |
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41 | (1) |
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Differential Diagnosis of Chest Pain |
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41 | (1) |
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Life-threatening Causes of Chest Pain in the Emergency Department |
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41 | (2) |
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41 | (1) |
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41 | (1) |
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42 | (1) |
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43 | (1) |
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43 | (1) |
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Epidemiology of Chest Pain in Primary Care and Emergency Department Settings |
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43 | (1) |
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Typical/Atypical Symptoms |
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43 | (1) |
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Patients Frequently Presenting With Atypical Symptoms |
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43 | (1) |
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43 | (1) |
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Features Not Characteristic of Myocardial Ischaemia |
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43 | (1) |
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Cardiac Enzymes in the Management of Acute Chest Pain |
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44 | (1) |
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Risk Stratification in Patients With Chest Pain |
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44 | (1) |
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45 | (1) |
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Parenteral Anticoagulant Therapy in Patients With ACS |
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46 | (3) |
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46 | (1) |
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46 | (1) |
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47 | (1) |
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48 | (1) |
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6 Common Causes of ST Elevation in ECG |
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49 | (10) |
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Case 8 Scenario: Julia With Chest Pain and ST Elevation |
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49 | (1) |
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49 | (3) |
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ECG in Acute Myocardial Infarction |
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52 | (1) |
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Other Causes of ST Elevation |
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52 | (4) |
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ECG Criteria for Diagnosing Left Ventricular Hypertrophy |
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52 | (1) |
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ST Elevation in Takotsubo Cardiomyopathy |
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52 | (2) |
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ST Elevation in Pericarditis |
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54 | (1) |
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ST Elevation in Early Repolarisation |
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54 | (1) |
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Normal Variant ST Elevation |
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54 | (1) |
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ST Elevation in Left Bundle Branch Block (LBBB) |
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54 | (2) |
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ECG Features of Hyperkalaemia |
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56 | (1) |
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ECG Features of Left Ventricular Aneurysm |
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56 | (1) |
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ECG Features of Brugada Syndrome |
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56 | (1) |
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ECG Features of Pulmonary Embolism |
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56 | (1) |
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ST Elevation in Coronary Artery Spasm |
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56 | (1) |
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56 | (3) |
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7 Coronary Artery Disease |
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59 | (10) |
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Case 9 Scenario: Dawn With Non-ST Elevation Myocardial Infarction |
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59 | (1) |
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Pathogenesis of Angina Pectoris in Stable Coronary Artery Disease |
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59 | (2) |
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Stent Failure: Stent Thrombosis vs Restenosis |
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59 | (1) |
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59 | (2) |
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61 | (1) |
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Predictors of Stent Thrombosis |
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61 | (1) |
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Investigating Coronary Artery Disease |
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61 | (4) |
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61 | (1) |
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62 | (1) |
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62 | (3) |
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Invasive Coronary Angiography |
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65 | (1) |
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Pharmacological Management of Stable Coronary Disease |
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65 | (1) |
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Revascularisation vs Medical Therapy |
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65 | (4) |
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69 | (8) |
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Case 10 Scenario: Paul With Systolic Murmur |
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69 | (1) |
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Definition of Sudden Cardiac Death |
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70 | (1) |
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Aetiology of Sudden Cardiac Death |
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70 | (1) |
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Structural Cardiac Abnormalities |
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70 | (4) |
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Hypertrophic Cardiomyopathy |
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70 | (3) |
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Arrhythmogenic Right Ventricular Cardiomyopathy |
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73 | (1) |
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Congenital Coronary Artery Anomaly |
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74 | (1) |
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Other Structural Heart Abnormalities |
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74 | (3) |
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Primary Electrophysiological Disease |
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74 | (1) |
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Acquired Cardiac Abnormalities |
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75 | (2) |
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77 | (8) |
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Case 11 Scenario: David With Chest Pain |
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77 | (1) |
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Clinical Assessment of Chest Pain |
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77 | (1) |
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Common Conditions That Cause Chest Pain |
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77 | (1) |
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Clinical Features of Pericarditis |
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77 | (1) |
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78 | (1) |
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Stages of Development of ECG Changes in Pericarditis |
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78 | (1) |
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78 | (1) |
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79 | (1) |
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Management of Pericarditis |
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79 | (6) |
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Clinical Signs of Pericardial Effusion |
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80 | (1) |
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Assessment of Cardiac Tamponade |
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80 | (1) |
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Mechanism and Measurement of Pulsus Paradoxus |
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80 | (2) |
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Complications of Acute Pericarditis |
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82 | (1) |
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82 | (1) |
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Causes of Pericardial Effusion |
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82 | (3) |
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10 Cardiac Biomarker Troponin in Clinical Medicine |
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85 | (10) |
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Case 12 Scenario: Laura With Troponin Elevation |
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85 | (1) |
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85 | (1) |
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Histology of Cardiac Myocytes and Troponin Complex |
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86 | (1) |
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Mechanism of Troponin Release |
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86 | (1) |
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Type I vs Type II Myocardial Infarction |
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86 | (5) |
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Troponin in Sepsis and Septic Shock |
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86 | (3) |
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Troponin Elevation in Pulmonary Embolism |
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89 | (1) |
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Troponin Elevation in Renal Failure |
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89 | (1) |
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Troponin Elevation in Heart Failure |
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89 | (1) |
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90 | (1) |
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Troponin Elevation in Stroke |
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90 | (1) |
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Takotsubo Cardiomyopathy and Troponin |
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91 | (1) |
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91 | (1) |
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Other Causes of Troponin Elevation |
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91 | (1) |
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Impact of New Highly Sensitive Troponin Assays in Clinical Decision Making |
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92 | (3) |
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11 Takotsubo Cardiomyopathy |
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95 | (8) |
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Case 13 Scenario: Edith With Chest Pain and Dyspnoea |
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95 | (1) |
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95 | (1) |
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The History of Takotsubo Cardiomyopathy and Its Nomenclature |
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95 | (1) |
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Pathogenesis of Takotsubo Cardiomyopathy |
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96 | (1) |
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Presentation of Takotsubo Cardiomyopathy |
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97 | (1) |
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98 | (1) |
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ECG Changes in Takotsubo Cardiomyopathy |
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98 | (1) |
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Investigations Including Cardiac Enzymes in Takotsubo Cardiomyopathy |
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98 | (1) |
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98 | (1) |
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Classification of Takotsubo Cardiomyopathy |
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98 | (1) |
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Prognosis and Complications of Takotsubo Cardiomyopathy |
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99 | (1) |
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Proposed Diagnostic Criteria |
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100 | (1) |
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Differential Diagnosis of Takotsubo Cardiomyopathy |
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100 | (1) |
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Management of Takotsubo Cardiomyopathy |
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100 | (3) |
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103 | (72) |
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Case 14 Scenario: June Has an Irregular Pulse |
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103 | (1) |
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Differential Diagnosis of an Irregularly Irregular Pulse |
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103 | (2) |
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Classification of Atrial Fibrillation |
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105 | (1) |
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The Treatment Strategy of Atrial Fibrillation |
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105 | (70) |
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Control of the Ventricular Rate (Rate Control) |
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106 | (1) |
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Achievement and Maintenance of Sinus Rhythm (Rhythm Control) |
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106 | (2) |
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Minimising the Risk of Thromboembolism |
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108 | (4) |
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Treatment of Underlying Conditions |
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112 | (3) |
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13 Perioperative Management of Anticoagulants/Antiplatelet Agents |
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115 | (1) |
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Case 15 Scenario: Mr Johnson With Hypertension and AF |
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115 | (1) |
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Case 16 Scenario: Mr Smith With Angina |
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115 | (1) |
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Oral Anticoagulant Therapy in the Periprocedural Period |
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116 | (1) |
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Predicting the Risk of Thrombosis |
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116 | (4) |
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Non-vitamin K antagonist oral anticoagulants During Surgery |
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120 | (1) |
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Restarting Non-vitamin K antagonist oral anticoagulants After Surgery |
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121 | (1) |
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Non-vitamin-K Antagonist Oral Anticoagulants vs Warfarin |
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121 | (1) |
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Factors to Consider Before Switching From Warfarin to NOAC After Surgery |
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121 | (1) |
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Perioperative Management of Antiplatelet Therapy |
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121 | (1) |
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122 | (3) |
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125 | (10) |
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Case 17 Scenario: David With Left Ventricular Hypertrophy |
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125 | (1) |
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Definition of Hypertension |
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125 | (1) |
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126 | (1) |
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Confirming the Diagnosis of Hypertension |
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126 | (1) |
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Primary and Secondary Hypertension |
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126 | (1) |
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Primary (Idiopathic or Essential) Hypertension |
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126 | (1) |
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126 | (1) |
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127 | (1) |
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127 | (1) |
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128 | (7) |
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128 | (1) |
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Pharmacological Treatment |
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129 | (1) |
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Mono Therapy vs Combination Treatment |
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130 | (1) |
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130 | (1) |
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131 | (1) |
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Device-Based Therapy for Hypertension |
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132 | (1) |
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Whom to Refer to a Specialist |
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132 | (3) |
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135 | (18) |
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Case 18 Scenario: Robert With Dyspnoea |
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135 | (1) |
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Definition of Heart Failure |
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136 | (1) |
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Symptoms of Heart Failure |
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136 | (1) |
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Incidence and Prevalence of Heart Failure |
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136 | (1) |
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137 | (1) |
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137 | (1) |
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Classification of Heart Failure |
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138 | (1) |
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Heart Failure With Reduced Systolic Function |
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138 | (1) |
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Heart Failure With Preserved Systolic Function |
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138 | (1) |
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Diagnostic Criteria for Heart Failure With Preserved Systolic Function |
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138 | (1) |
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Heart Failure With Preserved Systolic Function- Differential Diagnosis |
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138 | (1) |
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Investigating Heart Failure |
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138 | (2) |
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139 | (1) |
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139 | (1) |
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B-type Natriuretic Peptides |
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139 | (1) |
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Management of Heart Failure With Reduced Systolic Function |
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140 | (7) |
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Non-Pharmacological Management |
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140 | (1) |
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Pharmacological Management |
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140 | (3) |
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Role of Other Drugs in the Treatment of Heart Failure With Reduced Systolic Function |
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143 | (4) |
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147 | (1) |
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Device Therapy for Heart Failure With Reduced Systolic Function |
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147 | (6) |
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Implantable Cardioverter Defibrillators |
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148 | (1) |
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Cardiac Resynchronisation Therapy |
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148 | (5) |
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153 | (14) |
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Case 19 Scenario: Jessie With Loss of Consciousness |
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153 | (1) |
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Case 20 Scenario: Rhiannon With Transient Loss of Consciousness |
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153 | (1) |
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153 | (1) |
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Classification of Syncope By Cause |
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154 | (1) |
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Differential Diagnosis of Syncope |
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154 | (1) |
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Pathophysiology of Syncope |
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154 | (1) |
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Assessing a Patient With Syncope |
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155 | (1) |
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Clinical Features That Can Suggest a Diagnosis After Initial Assessment |
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155 | (1) |
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155 | (1) |
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Syncope due to Orthostatic Hypotension |
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155 | (1) |
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155 | (1) |
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Investigating a Patient With Syncope |
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156 | (2) |
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156 | (1) |
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156 | (1) |
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Electrocardiographic Monitoring |
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156 | (1) |
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Exercise Stress Test (EST) |
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157 | (1) |
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Head-up Tilt Table Test (HUTT) |
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157 | (1) |
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Echocardiography and Other Cardiac Imaging Modality |
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157 | (1) |
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Electrophysiological (EP) Study |
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157 | (1) |
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Management of Vasovagal Syncope |
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158 | (1) |
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Non-pharmacological Treatment |
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158 | (1) |
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Pharmacological Treatment |
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158 | (1) |
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Pacemakers in Vasovagal Syncope |
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158 | (1) |
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Treatment of Cardiac Syncope |
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159 | (2) |
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17 Coronavirus Disease 2019 |
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161 | (1) |
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Case 21 Scenario: Peter With Dyspnoea, Dry Cough and Fever |
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161 | (1) |
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161 | (1) |
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162 | (1) |
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162 | (1) |
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Cardiovascular Conditions and COVID-19 Infection |
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162 | (2) |
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Elevated Biomarkers: Troponin and Natriuretic Peptides |
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162 | (1) |
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163 | (1) |
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Cardiomyopathy and Heart Failure |
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163 | (1) |
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Renin-active Agents in COVID-19 Infection |
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163 | (1) |
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164 | (1) |
Index |
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165 | |