Meet the author |
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vii | |
Acknowledgements |
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viii | |
Foreword |
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ix | |
Praise for the first edition |
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xi | |
Introduction |
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1 | (3) |
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The structure of this book |
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2 | (1) |
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2 | (2) |
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4 | (24) |
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4 | (2) |
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1.2 Aetiology of mental illness |
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6 | (2) |
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1.3 Neurodevelopmental theories |
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8 | (5) |
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Neurons and neurotransmitters |
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8 | (5) |
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1.4 Clinical decision making in practice, and medicine management and optimisation |
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13 | (15) |
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Psychosocial interventions in mental health settings |
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20 | (8) |
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2 Drugs Used In Psychoses |
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28 | (69) |
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28 | (3) |
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28 | (1) |
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29 | (2) |
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31 | (12) |
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32 | (3) |
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35 | (2) |
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37 | (6) |
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2.3 Dose and administration |
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43 | (21) |
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43 | (8) |
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Non-restrictive interventions |
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51 | (3) |
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An tipsychotic drugs in depot preparation |
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54 | (5) |
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Cytochrome P450 drug-metabolising enzymes interaction with psychotropics |
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59 | (5) |
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2.4 Adverse effects and management |
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64 | (28) |
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Extrapyramidal side effects |
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64 | (2) |
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66 | (1) |
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Drug-induced parkinsonism |
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67 | (2) |
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69 | (2) |
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71 | (1) |
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Non-extrapyramidal adverse effects of antipsychotic drugs |
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72 | (10) |
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Allergic and dermatological effects |
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82 | (1) |
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Haematological adverse effects |
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83 | (1) |
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Obligatory monitoring for clozapine therapy |
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84 | (2) |
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Neuroleptic malignant syndrome |
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86 | (2) |
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Improving physical health needs in SMI: best practice monitoring |
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88 | (2) |
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Behavioural change initiatives alongside routine physical health monitoring |
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90 | (1) |
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Lester Cardiometabolic Tool |
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90 | (1) |
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National Early Warning Score 2 (NEWS 2) |
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91 | (1) |
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91 | (1) |
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2.5 Medication adherence in mental health settings |
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92 | (5) |
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3 Drugs Used In Depression |
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97 | (35) |
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97 | (10) |
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ICD-11: key changes in relation to depression diagnostic criteria |
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99 | (1) |
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Screening for depression and anxiety in primary care settings |
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100 | (1) |
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Co-morbid psychiatric presentations |
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101 | (2) |
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Key points about assessment and management of symptoms of depression and anxiety in primary care |
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103 | (4) |
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107 | (3) |
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Monoamine theory of depression |
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107 | (3) |
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3.3 Dose and administration |
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110 | (6) |
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3.4 Adverse effects and management |
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116 | (11) |
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Tricyclic antidepressants |
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116 | (2) |
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Selective serotonin reuptake inhibitors |
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118 | (3) |
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Serotonin-noradrenaline reuptake inhibitors |
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121 | (1) |
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Tetracyclic (noradrenergic and specific serotonergic antidepressants) |
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122 | (1) |
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123 | (1) |
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Monoamine oxidase inhibitors |
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124 | (2) |
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126 | (1) |
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3.5 Differences in therapeutic effects of antidepressants |
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127 | (5) |
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132 | (15) |
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132 | (2) |
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Dementia assessment and diagnosis: best practice |
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133 | (1) |
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134 | (2) |
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Acetylcholinesterase inhibitors |
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134 | (2) |
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4.3 Dose and administration |
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136 | (1) |
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4.4 Adverse effects and management |
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137 | (3) |
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Acetylcholinesterase inhibitors |
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137 | (1) |
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138 | (1) |
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Polypharmacy in the older person |
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139 | (1) |
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Antipsychotic therapy in the care of the older person |
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140 | (1) |
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4.5 Memantine (NMDA receptor antagonist) |
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140 | (7) |
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140 | (1) |
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Concomitant use of cholinesterase inhibitors and memantine |
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141 | (1) |
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Adverse effects and management of memantine |
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141 | (6) |
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5 Drugs Used In Bipolar Disorder |
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147 | (24) |
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147 | (4) |
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The aetiology of bipolar disorder |
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148 | (1) |
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Bipolar disorder clinical presentation and management |
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149 | (2) |
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151 | (1) |
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5.3 Dose and administration |
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152 | (6) |
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153 | (2) |
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155 | (1) |
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156 | (1) |
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157 | (1) |
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5.4 Adverse effects, monitoring and management |
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158 | (13) |
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158 | (4) |
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162 | (2) |
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164 | (2) |
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166 | (5) |
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6 Drugs Used In Anxiety Disorders |
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171 | (21) |
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171 | (3) |
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172 | (2) |
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174 | (4) |
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Benzodiazepine hypnotics and anxiolytics |
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174 | (1) |
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Non-benzodiazepine hypnotics |
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175 | (1) |
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176 | (1) |
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Non-benzodiazepine anxiolytics |
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176 | (2) |
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6.3 Dose and administration |
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178 | (2) |
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6.4 Adverse effects and management |
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180 | (12) |
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Adverse effects of benzodiazepines |
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180 | (1) |
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Withdrawal from benzodiazepines |
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181 | (1) |
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Risk of overdose with benzodiazepines |
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182 | (1) |
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Adverse effects of non-benzodiazepine hypnotics (Z-drugs) |
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183 | (4) |
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Adverse effects of non-benzodiazepine anxiolytics |
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187 | (5) |
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7 Drugs Used In Alcohol And Substance Misuse |
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192 | (56) |
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192 | (3) |
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7.2 Most vulnerable groups to substance use disorders |
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195 | (1) |
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7.3 The mesolimbic dopamine circuit as the key reward pathway component |
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196 | (3) |
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How does cocaine and methamphetamine use affect the functioning of the reward circuit? |
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198 | (1) |
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7.4 Drug tolerance, dependence, addiction |
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199 | (3) |
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199 | (1) |
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200 | (1) |
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201 | (1) |
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7.5 The psychopharmacology of commonly used drug substances and their effects |
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202 | (17) |
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202 | (17) |
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7.6 Care planning and management of substance misuse disorders |
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219 | (4) |
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7.7 Medications used to treat alcohol dependence, smoking cessation and other drug dependencies |
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223 | (25) |
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235 | (2) |
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Severe mental illness and smoking cessation |
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237 | (11) |
Appendix: Answers to chapter review questions and MCQs |
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248 | (29) |
Glossary |
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277 | (10) |
References |
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287 | (22) |
Index |
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309 | |