This Monograph brings together within one cover the current knowledge about tumors of the nasal passages in man, in domestic and nondomestic animals. and in the rodents which are commonly employed in carcinogenesis studies in the laboratory.
1. Nasal Airway Anatomy and Inhalation Deposition in Experimental
Animals and People
2. The Pathogenesis of Nasal Neoplasia Induced by
Alkylating and Aldehyde Compounds
3. Nitrosamine-Induced Nasal Cavity
Carcinogenesis
4. Experimental Nasal Cavity Tumors Induced by
Tobacco-Specific Nitrosamines
5. Histopathology of the Nasal Cavity in
Laboratory Animals Exposed to Cigarette Smoke and Other Irritants
6.
Radiation-Induced Nasal Cavity Tumors in Animals
7. Nasal Cavity Cancer in
Laboratory Animal Bioassays of Environmental Compounds
8. Epstein-Barr virus
and Nasopharyngeal Carcinoma
9. Studies on the Relationship between
Epstein-Barr (Virus (EBV) and Nasopharyngeal Carcinoma (NPC) in China
10.
Nasal Cavity Carcinogens: Possible Routes of Metabolic Activation
11.
Metabolism of N-Nitrosames by the Nasal Mucosa
12. Summary and Conclusions
Index
Gerd Reznik, D. V. M., Ph.D., is Directory of the Institute for Pathology and Toxicology, Byk-Gulden Pharmaceuticals in Hamburg, Germany.
Sherman F. Stinson, Ph.D., is an experimental pathologist currently affiliated with the Labotatory of Experimental Pathology of the National Cancer Institute, Frederick Cancer Research Facility, Frederick, Md.
