Section I: Anatomy, physiology, and general principlesAnterior skull base anatomy
Lateral skull base anatomy
CSF physiology
Diagnosis of CSF leak
Imaging for detection of CSF leaks
Conservative and medical therapy for CSF leaks
CSF division
Anesthesia considerations in skull base reconstruction
Allografts in skull base reconstruction
Section II: Anterior skull base pathology
Traumatic and iatrogenic CSF leaks
Congenital encephaloceles
Anterior skull base surgical approaches
Section III: Lateral skull base surgical approaches
Traumatic and iatrogenic CSF leaks
Spontaneous CSF leaks and encephaloceles
Lateral skull base surgical approaches
Section IV: Anterior skull base reconstruction
Free graft techniques
Local vascularized pedicled flaps
Extracranial flaps
Microvascular reconstruction
Reconstruction of the frontal and ethmoid defects
Reconstruction of sphenoid defects: lateral recess, sellar, tuberculum, and planum defects
Reconstruction of the clival and craniocervical junction defects
Section V: Lateral skull base reconstruction
Management of CSF leaks during otologic surgery
General repair principles following posterior cranial base surgery
Reconstruction of the middle cranial fossa floor
Reconstruction of large temporal bone defects
Section VI: Postoperative care
Post operative management following skull base reconstruction
Management of the postoperative leak
Other complications following skull base reconstruction
Outcomes of anterior skull base reconstruction
Outcomes of lateral skull base reconstruction
Medicolegal issues in skull base reconstruction
Section VII: Future applications
Emerging developments in skull base reconstruction.
Edward C. Kuan, MD, MBA, Departments of Otolaryngology-Head and Neck Surgery and Neurological Surgery, University of California, Irvine, Irvine, CA, USA
Bobby A. Tajudeen, MD, Department of Otorhinolaryngology-Head and Neck Surgery, Rush University Medical Center, Chicago, IL, USA
Hamid R. Djalilian, MD, Departments of Otolaryngology-Head and Neck Surgery, Neurological Surgery, and Biomedical Engineering, University of California, Irvine, Irvine, CA, USA
Harrison W. Lin, MD, Department of Otolaryngology-Head and Neck Surgery and Neurological Surgery, University of California, Irvine, Irvine, CA, USA