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E-grāmata: Stem Cell, Regenerative Medicine and Cancer

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  • Formāts: 777 pages
  • Izdošanas datums: 01-Feb-2016
  • Izdevniecība: Nova Science Publishers Inc
  • ISBN-13: 9781617613425
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  • Formāts: 777 pages
  • Izdošanas datums: 01-Feb-2016
  • Izdevniecība: Nova Science Publishers Inc
  • ISBN-13: 9781617613425
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Of the estimated trillion cells that build up our bodies, only a little number can self-renew and give rise to many different cell types. These unspecialized cells are called stem cells. Stem cell division and differentiation is fundamental to the development of the mature organism. Stem cells have recently attracted significant attention largely due to their potential medical benefits in the fields of therapeutic cloning and regenerative medicine. Because stem cells can become many specialized types of cells of the organs, they have the potential to treat many diseases, including Alzheimer's disease, Parkinson's disease, type-1 diabetes, spinal cord injury, stroke, burns, heart disease, osteoarthritis, and rheumatoid arthritis. This book focuses on the application of stem cells in regeneration and repair of the organs in disease and aging.
Preface ix
Contributors xiii
Part I Stem Cells in Tissue Regeneration and Repair
Chapter 1 Epigenetic Modifications in Reprogramming and Lineage Specifications from Embryonic Stem Cells: Current Trends and Relevance in Developing Regenerative Medicine
3(28)
Jinnuo Han
Henry Chung
Perminder S. Sachdev
Kuldip S. Sidhu
Chapter 2 Regenerative Medicine: Lessons from Planarians
31(40)
Francesc Cebria
Teresa Adell
Emili Salo
Chapter 3 Mesenchymal Stem Cells in Tissue Regeneration and Organogenesis Using a Porcine Model
71(48)
B. Mohana Kumar
Gyu Jin Rho
Chapter 4 Retinal Stem Cells, Signaling and Regeneration
119(22)
Fumi Kubo
Chapter 5 A Pathophysiological View of the Neural Stem Cell Niche
141(16)
Ricardo Pardal
Aida Platero-Luengo
Chapter 6 Adult Stem and Transit-Amplifying Cells in Repair through Granulation Tissue: Role of the Pericytic Vasculature Niche
157(30)
Lucio Diaz-Flores
Ricardo Gutierrez
Juan F. Madrid
Hugo Alvarez-Arguelles
Francisco Valladares
Lucio Diaz-Flores
Chapter 7 Stem Cells in Tooth Development and Regeneration
187(22)
Masaki J. Honda
Hayato Ohshima
Chapter 8 Role of Stem Cells in Lung Injury
209(22)
Ana L. Mora
Mauricio Rojas
Chapter 9 Gene Modification and Stem Cell Transplantation for Regenerating the Mammalian Inner Ear: A New Approach in the Treatment of Sensorineural Hearing Loss
231(50)
Petros V. Vlastarakos
Thomas P. Nikolopoulos
Chapter 10 Putative Stem Cells in Mucosas of the Esophago-Gastrointestinal Tract
281(30)
Carlos A. Rubio
Chapter 11 Stem and Progenitor Cells in Muscle Regeneration and Potential Treatment
311(38)
Anna Burdzinska
Chapter 12 Stem Cells in Kidney Regeneration and Cancer
349(20)
Shree Ram Singh
Chapter 13 Stem Cell Treatment for Complicated Diabetes
369(30)
Jong Yoon Bahk
Jae Hun Jung
Seung Ki Min
Hoon Han
Chapter 14 Deterioration of Hematopoietic Stem Cells with Aging
399(28)
MiJung Kim
Seung Ah Kim
Chan Jeoung Park
Jong Jin Seo
Gerald J. Spangrude
Chapter 15 MicroRNAs in Skin Morphogenesis and Diseases
427(14)
Damjan Glavac
Chapter 16 Effect of Cellular Microenvironment and Paracrine Signals on Chondrogenic Differentiation of Mesenchymal Progenitor Cells
441(26)
Susanne Grassel
Rita Dreier
Chapter 17 Hypoxia-Inducible Factor, Osteogenesis and Chondrogenesis
467(10)
Yiyong Wei
Xiaotang Sun
Chapter 18 Nanotechnology in the Stem Cells Research and Development: Imaging and Therapies for Injuries and Degenerative Diseases
477(38)
Jiajia Ji
Daxiang Cui
Part II Stem Cell in Cancer and Drug Discovery
Chapter 19 Cancer Stem Cells: Light and Shadows
515(14)
Caterina AM La Porta
Chapter 20 Stem Cells in Head and Neck Cancer: A Key to the Future?
529(8)
Chiara Bianchini
Andrea Ciorba
Roberta Piva
Stefano Pelucchi
Antonio Pastore
Chapter 21 Stem Cell and Oral Squamous Cell Carcinoma Tumorigenesis
537(40)
Wan-tao Chen
Zhi-yuan Zhang
Ping Zhang
Qin Xu
Lai-ping Zhong
Hong-ya Pan
Ming Yan
Dong-xia Ye
P. Sdek
Wei-liu Qiu
Chapter 22 Mammary Epithelial and Breast Cancer Stem Cells
577(28)
Brian J. Morrison
Brent A. Reynolds
Chris W. Schmidt
J. Alejandro Lopez
Chapter 23 Stem Cells and Breast Cancer
605(18)
Benedetta Bussolati
Cristina Grange
Anna Sapino
Giovanni Camussi
Chapter 24 Notch Signaling in Cancer, Stem Cells and Cancer Stem Cells
623(20)
Jeevisha Bajaj
Deepa Subramanyam
Sudhir Krishna
Chapter 25 Epithelial-to-Mesenchymal Transition, Stem Cells, and Cancer Progression
643(24)
Joseph H. Taube
Sendurai A. Mani
Chapter 26 Cancer Stem Cells in Prostate Adenocarcinoma
667(28)
Daniela Fioriti
Anna Bellizzi
Franco Di Silverio
Fernanda Chiarini
Valeria Pietropaolo
Chapter 27 Heat Shock Proteins in Normal and Cancer Stem Cell Biology: Implications for Regenerative and Chemotherapeutic Medicine
695(22)
Earl Prinsloo
Leanne C. Cooper
Buhle Moyo
Jo-Anne de la Mare
Jessica C. Lawson
Adrienne Edkins
Gregory L Blatch
Chapter 28 Human Embryonic Stem Cell Platforms in Drug Screening and Predictive Toxicology
717(20)
Kaushik Dilip Deb
Index 737