Stem Cells and Signaling Pathways provides mechanistic insights into the role of stem cells to combat the COVID-19 outbreak and other pathologies where a cytokine storm is the cause of concern for e.g., radiation exposure, multiple organ failure and sepsis. The advent of SARS-CoV-2 resulted in a global pandemic, putting individuals with other comorbidities at a higher risk of infection. The whole world witnessed a massive shortage of medical and other essential supplies needed to combat the virus. That said, stem cell therapy has emerged as a potential treatment for viral diseases, including but not limited to COVID-19.
Interestingly, the clinical trials in the patients having COVID-19 complications depicted faster recovery in patients post mesenchymal stem cells therapy owing to the decreased cytokines levels, anti-viral effects and regeneration of the infected tissue.
- Evaluates the role of MSCs to combat cytokine storm, the challenges regarding COVID-19 therapy, and how they can be countered with the use of stem cells and the risk of opportunistic infections post COVID-19
- Presents how stem cell therapy has emerged as a potential treatment for viral diseases, including but not limited to COVID-19
- Provides a detailed understanding of the novel coronavirus, with an emphasis on the therapeutic aspects
1. Regulation of mesenchymal stem cell differentiation by key cell
signaling pathways
2. Stem signaling molecules and pathways: Implications in the regulation of
fate and proliferation
3. The role of Yamanaka factors in induced pluripotent stem cells and
embryonic stem cells signaling
4. Purinergic signaling in stem cell growth
5. Cutaneous Homeostasis: A Balancing Cross-Talk Between Epidermal Stem Cell
Pool and Regulatory Pathways
6. Role of Stem Cells in Cardiac Bioengineering
7. Stem Cell Signaling Molecules and Pathways in Liver Regeneration
8. Role of stem cells in osteoblastic miRNA and bone tissue regeneration
9. Stem cells and Signaling Pathways in Human Reproductive System
10. Hormonal Impacts on Stem Cell Lineages and Related Signaling Pathways
11. Unravelling the crosstalk of Hedgehog with Wnt, Notch, and TGF-
signaling pathways
12. Stem cell aging: Role of signaling pathways and microRNAs
13. Slowdown of ageing and neurodegenerative diseases by extremolytes
14. Stem cells and therapy; cancer stem cells and targeted therapy with DNA
repair inhibitors
15. The potential role of stem cells in multiple sclerosis therapies
16. Stem cells signaling pathways and surface receptors: implications for
Multiple Sclerosis treatment
17. Mechanistic role of stem cells in the pathogenesis and treatment of oral
diseases: current insights and future directions
18. Stem cell-based approach in treatment of periodontitis
19. Role of probiotics in modulation of stem cell progeny in human
gastrointestinal disorders
20. Implications of stem cell-associated signals in pathogenesis of lipid
disorders
21. Stem cell's potential role in the treatment of diabetes mellitus
22. Mesenchymal Stem Cells in Chronic Kidney Disease and Therapeutic
Signaling Pathways
23. Current Advances and Challenges in Stem Cell-Based Therapy for Chronic
Kidney Disease
24. Stem cell therapeutic approaches and signaling pathways in rheumatoid
arthritis and osteoarthritis
25. Potential role of stem cells in pathogenesis of endometriosis.
26. Potential role of traditional medicine in stem cell research
Prof. Surajit Pathak, PhD, is currently working as a professor at Chettinad Academy of Research and Education (CARE), Chennai, India (from 2015 to date). He is currently serving as a principal research scientist (2022 JuneDec 2022) at Linkoping University, Linkoping, Sweden. He received his PhD degree from India in 2007 and completed his postdoctoral training (200715) from the University of Alabama, United States, the University of Padova, Italy, and the University of Linkoping, Sweden. His current research focuses on Biomarker discoveries for early detection of colorectal cancer. He has published more than 100 research articles in peer-reviewed international journals of repute with 2233 citations and 27 H-index. Dr. Pathak has edited Elsevier book Stem Cells and Aging in 2021. He is the member of various professional research bodies of India, including the Indian Association of Cancer Research and the Indian Science Congress. Dr. Antara Banerjee, PhD, is presently working as an associate professor at CARE, Chennai from 2016 to date. After completing her PhD in 2008 from India, Dr. Banerjee pursued her postdoctoral work at the University of Padova, Italy and Linkoping University, Sweden (200915). She has published over 95 peer-reviewed research articles in international and national journals with citation index-1408 and H-index 19. The Banerjees lab at Chettinad Hospital and Research Institute is now focused on understanding the role of mesenchymal stem cells niche in tissue regeneration and exploring signaling pathways in governing stem cell fate. She is the editor of Elsevier book Stem Cells and Aging in 2021. She is the member of various professional research bodies, including the Indian Association of Cancer Research and the Indian Science Congress.
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