Strategies to Modify the Drug Release from Pharmaceutical Systems, Second Edition serves as a vital reference on contemporary models aimed at achieving the precise therapeutic dosage and timing of drug release. The book provides updated strategies, mathematical models, routes of administration, and technologies, all presented succinctly and objectively. This six-chapter guide covers general concepts of drug release modification and classification of therapeutic systems, including passive versus active targeting. It delves into mechanisms to control drug release, discussing materials and technologies, and introduces mathematical and physicochemical models of drug release.
Furthermore, it reviews drug delivery systems like 3D printing, nose-to-brain delivery, environmentally responsive systems, and new lipid systems, making it indispensable for pharmaceutical scientists, graduate students, materials scientists, and chemists.
1. General concepts
2. Modification of drug release
3. Classification of therapeutic systems for drug delivery
4. Main mechanisms to control the drug release
5. Mathematical and physicochemical models of drug release
6. Drug delivery systems
Marcos Luciano Bruschi, Ph.D., is Professor of Pharmaceutics andPharmaceutical Technology in the Department of Pharmacy at the State
University of Maringį (UEM), Paranį, Brazil. He gained a BSc in Pharmacy
(1996 - UEM, Brazil), a MD in Pharmaceutical Sciences (2002 - State University
of Sćo Paulo - UNESP - Brazil) and a PhD in Pharmaceutical Sciences (2006 -
University of Sćo Paulo - USP - Brazil and School of Pharmacy, Queens
University of Belfast, Northern Ireland, UK). In 2013-2014, he is accomplishing
a Post-Doctoral Degree in Pharmaceutics in the School of Pharmacy, Queens
University of Belfast (QUB - Northern Ireland, UK). He is registered with the
Brazilian Pharmaceutical Society and, in 1998, took up a lectureship in
Pharmaceutics in the School of Pharmacy, UEM, Brazil. In 1999, he was
appointed as a senior lectureship and to a personal Chair in Pharmaceutics and
Pharmaceutical Technology in 2006. His research concerns the development
and characterization of pharmaceutical dosage forms and drug delivery
systems, using natural or synthetic sources. Dr. Bruschis work has involved the
development of novel drug delivery systems, with particular emphasis on
micro/nanoparticles, semisolids, bio/mucoadhesives, thermoresponsive systems,
liquid crystaline phases, and natural products. He is the author of three Brazilian
patent requests and over 150 research papers/communications.
