This volume explores the recent advances in the study of translational paths in central inflammation and focuses on ongoing pathophysiological processes and the transition between inflammatory stages and progressive states with neurodegeneration. Chapters cover topics such as pathophysiological hallmarks of neuroinflammation from tissue damage to reorganization; connecting studies of mouse models; and investigations of humans with multiple sclerosis. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.
Cutting-edge and practical, Translational Methods for Multiple Sclerosis Research is a valuable resource for researchers who want to learn more about this chronic ad progressive disease, and pave the way for new advancements.
Pathophysiological Bases of Autoimmune Initiated/Mediated
Neurodegeneration.- Translational Animal Models for MS and Related
Neuroimmunological Disorders.- White Matter Pathology.- Pathophysiology of
Grey Matter Affection in MS.- Translational Characterization of Glia Role in
Multiple Sclerosis.- Translational Value of CSF and Blood Markers of
Autoimmunity and Neurodegeneration.- Spontaneous Mouse Models of
Neuroinflammation.- Chronic Progressive Models.- Electrophysiological
Measurements of Brain Network Characterization in Rodents.- Translation of
Functional Domain Abnormalities from Human to Mouse Motor
System.- Characterization of the Somatosensory System.- Translational
Research in Neuroimmunology: Cognition.- Models for Assessing Anxiety and
Depression in Multiple Sclerosis: From Mouse to Man.- Human Structural
MRI.- Human Functional MRI.- Functional Studies in Rodents.- Non-Invasive
Electrophysiology.- Targeting Acute Inflammation.- Translational Aspects of
Immunotherapeutic Targets in MS.- Therapeutic Strategies to Potentially Cure
Multiple Sclerosis: Insights into the Mechanisms of Autologous Hematopoietic
Stem Cell Transplantation.- Symptomatic MS Therapy.