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E-grāmata: Urothelial Carcinoma: Methods and Protocols

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  • Formāts: PDF+DRM
  • Sērija : Methods in Molecular Biology 2684
  • Izdošanas datums: 06-Jul-2023
  • Izdevniecība: Springer-Verlag New York Inc.
  • Valoda: eng
  • ISBN-13: 9781071632918
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Urothelial Carcinoma: Methods and ProtocolsPalielināt
  • Formāts: PDF+DRM
  • Sērija : Methods in Molecular Biology 2684
  • Izdošanas datums: 06-Jul-2023
  • Izdevniecība: Springer-Verlag New York Inc.
  • Valoda: eng
  • ISBN-13: 9781071632918
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This fully updated volume explores recently improved avenues to study urothelial carcinomas. Beginning with several novel chapters on molecular characterization and urothelial carcinogenesis, the book continues with sections on cellular and animal models, biomarkers, and approaches for targeted therapy. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. 

Authoritative and practical, Urothelial Carcinoma: Methods and Protocols, Second Edition serves as a valuable resource to further increase our knowledge on urothelial carcinoma and also to aid research on numerous other cancers.
Scoring Systems for Immunohistochemistry in Urothelial Carcinoma.- A
Panel-Based Method for the Reproduction of Distinct Molecular Subtype
Classifications of Muscle-Invasive Urothelial Bladder Cancer.- Analysis of
Mutational Signatures Using the mutSignatures R Library.- A Drug Repurposing
Pipeline Based on Bladder Cancer Integrated Proteotranscriptomics
Signatures.- Characterization of Native COMPASS Complex in Urothelial
Carcinoma Cells by Size Exclusion Chromatography.- Reconstructing
Phylogenetic Relationship in Bladder Cancer: A Methodological
Overview.- Using Sister Chromatid Exchange Assay to Detect Homologous
Recombination Deficiency in Epigenetically Deregulated Urothelial Carcinoma
Cells.- Identification of STAG2 Mutant Bladder Cancers by
Immunohistochemistry.- Genome-Wide CRISPR Screening for the Identification of
Therapy-Resistance-Associated Genes in Urothelial Carcinoma.- Tissue Slice
Culture and Analysis of Tumor-Associated Hyaluronan in Urothelial
Carcinoma.- NGS-Based Tumor-Informed Analysis of Circulating Tumor
DNA.- Considering the Effects of Modern Point-of-Care Urine Biomarker Assays
in Follow-Up of Patients with High-Risk Non-Muscle Invasive Bladder
Cancer.- Simplex Droplet Digital PCR Assays for the Detection of TERT
Promoter Mutations in Urine Samples for the Non-Invasive Diagnosis of
Urothelial Cancer.- Predictive Biomarkers of Response to Neoadjuvant Therapy
in Muscle Invasive Bladder Cancer.- Assessment of PD-L1 Status in Urothelial
Cancer.- Epigenetic Priming and Development of New Combination Therapy
Approaches.- Evaluation of FGFR Alteration Status in Urothelial
Tumors.- Antibody-Drug-Conjugates (ADC): A Novel Treatment Option in
Urothelial Carcinoma.- Intravesical Infusion of Oncolytic Virus CG0070 in the
Treatment of Bladder Cancer.- Analysis of ICAM-1 Expression on Bladder
Carcinoma Cell Lines and Infectivity and Oncolysisby Coxsackie Virus A21.
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