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E-grāmata: Vigor

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  • Formāts: EPUB+DRM
  • Izdošanas datums: 21-Jul-2020
  • Izdevniecība: MIT Press
  • Valoda: eng
  • ISBN-13: 9780262358705
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  • Formāts: EPUB+DRM
  • Izdošanas datums: 21-Jul-2020
  • Izdevniecība: MIT Press
  • Valoda: eng
  • ISBN-13: 9780262358705

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An examination of the link between the vigor with which we move and the value that the brain assigns to the goal of the movement.

Why do we reflexively run toward people we love, but only walk toward others? In Vigor, Reza Shadmehr and Alaa Ahmed examine the link between how the brain assigns value to things and how it controls our movements. They find that brain regions thought to be principally involved in decision making also affect movement vigor&;and that brain regions thought to be principally responsible for movement also bias patterns of decision making.

Shadmehr and Ahmed first consider the relationship of value and vigor from a behavioral and mathematical perspective, considering a series of fascinating observations&;including, for example, data showing that people in certain cities tend to walk faster than those living elsewhere&;through the lens of optimal foraging theory. They then go on to explore the neural basis of vigor and valuation, synthesizing results from experiments that have measured activity in various brain structures and neuromodulators, including dopamine and serotonin. They speculate that in the future, technologies may be able to predict our personal preferences by measuring our movements; through the vigor with which we move, we unwittingly reveal one of our well-guarded secrets: how much we value the object of our attention.

Preface vii
Acknowledgments xv
1 The Effort of Movement
1(32)
1.1 Choosing, Moving, Then Harvesting
1(2)
1.2 A Measure of Effort
3(10)
1.3 Utility of a Movement
13(7)
1.4 Additive versus Multiplicative Interaction of Reward and Effort
20(1)
1.5 Temporal Discounting of Effort
21(3)
1.6 Alternative Representations of Effort
24(3)
1.7 Cognitive Effort versus Movement Effort
27(6)
2 Movements and Decisions in a Normative Framework
33(44)
2.1 Optimal Foraging Theory
35(8)
2.2 Marginal Value Theorem
43(8)
2.3 Optimizing Movement Vigor
51(5)
2.4 Example: Walking Speed
56(4)
2.5 Walking Speed at Various Cities
60(2)
2.6 Foraging with Our Eyes
62(7)
2.7 Salience versus Utility
69(8)
3 Reaction Time and Deliberation
77(52)
3.1 Latency to Start a Movement: The LATER Model
80(3)
3.2 The Variable Threshold Model
83(1)
3.3 Linking Latency and Utility
84(4)
3.4 Reward Modulates Vigor
88(7)
3.5 Effort Modulates Vigor
95(3)
3.6 Rate of Reward Modulates Vigor
98(3)
3.7 Deliberation and Decision-Making
101(6)
3.8 Modulation of Saccade Vigor during Decision-Making
107(5)
3.9 Decision Uncertainty and Vigor of Movements
112(2)
3.10 Between-Subject Differences in Vigor
114(5)
3.11 Decision-Making and Movement Traits of Individuals
119(10)
4 Neural Prelude to a Movement
129(46)
4.1 Superior Colliculus
130(4)
4.2 Bursting to Move
134(4)
4.3 Bursting to Hold Still
138(6)
4.4 Movement Latency and the Activity in the Fovea-Related Cells
144(4)
4.5 Movement Latency and the Rate of Rise in the Buildup Cells
148(4)
4.6 Reaction Time as an Interaction between Utility of Holding versus Utility of Moving
152(4)
4.7 Salience versus Utility
156(1)
4.8 Effect of Reward on the Colliculus
157(5)
4.9 Reacting Much Earlier
162(7)
4.10 Influencing Decisions with Manipulation of the Colliculus
169(6)
5 Cortical Computation of Utility
175(56)
5.1 Moving without Computation of Utility
177(2)
5.2 Attention and the Effort Cost of Movement
179(5)
5.3 Inhibiting Reflexive Behavior
184(4)
5.4 Activity in the FEF during the Reaction Time Period
188(5)
5.5 FEF and Deciding Where to Direct Gaze
193(9)
5.6 Setting a Threshold to Move: Omnipause Neurons
202(4)
5.7 The Premotor Cortex and the Decision to Reach
206(6)
5.8 Encoding Utility and Salience in the Parietal Cortex
212(8)
5.9 Good-Based versus Action-Based Models of Decision-Making
220(4)
5.10 Deciding When to Leave
224(7)
6 Basal Ganglia and the Motivation to Move
231(58)
6.1 Anatomy of the Basal Ganglia
233(1)
6.2 Substantia Nigra Reticulata
234(10)
6.3 Caudate
244(12)
6.4 Dopamine and the Pleasure of Moving
256(22)
6.5 Dopamine and the Willingness to Exert Effort
278(11)
7 Serotonin and the Promotion of Sloth
289(34)
7.1 Anatomy of the Serotonergic System
290(2)
7.2 Serotonin and the Average Reward Rate
292(3)
7.3 Serotonin and the Willingness to Wait
295(11)
7.4 Serotonin and Movement Vigor
306(6)
7.5 Serotonin, Dopamine, and the Willingness to Work
312(4)
7.6 Serotonin and Motoneuron Activity
316(7)
Conclusions 323(6)
Appendix A Effective Mass of the Human Arm 329(2)
Appendix B Alternate Forms of Utility 331(2)
Appendix C Algebra of Random Variables 333(4)
References 337(12)
Index 349