A comprehensive presentation of the current knowledge of vitamin E and the state-of-the-art in vitamin E research, for biochemists, physiologists, pharmacologists, and public health researchers. The 67 contributed chapters are organized in six sections: natural occurrence and tissue levels; chemistry, biochemistry, and cell biology; pharmacology; pathophysiological conditions and vitamin E; medical applications; and future perspectives. Annotation copyright Book News, Inc. Portland, Or.
Probes developments and trends in research and clinical applications of vitamin E, discussing its chemistry and biochemistry and natural occurence in nuts, seeds, whole grains and vegetable and fish-liver oils. The book covers new findings on the role of vitamin E as a biological response modifier.
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". . .the ultimate treatise on vitamin E. . .exceeding all previous texts in detail and consistency. . . Everyone working in the area of vitamin E research should own this volume. . .Every graduate student interested in nutrition should be required to read this book not only for basic knowledge, but to examine the variety of ways researchers approach experimental design. " ---Journal of the American Dietetic Association "This extensive book discusses present and past studies into the links between Vitamin E and the risks of a number of chronic and acute health problems. . . .particularly useful for biochemists, pharmacologists, public health researchers and research dietitians. " ---International Journal of Cardiology ". . .a significant contribution to the field. . .This impressive work is composed of. . .67 chapters, authored and coauthored by more than 125 international scientific and clinical experts in vitamin E research. . . .a reference work for toxicologists, research scientists, and physicians specializing in dermatology, neurology, pediatrics, ophthalmology, and internal medicine. They need to be both aware of and knowledgeable in the findings presented here for their experiments, research, and clinical practice. " ---Journal of Toxicology: Cutaneous & Ocular Toxicology
"NATURAL OCCURRENCE AND TISSUE LEVELS Plants Natural Sources of
Tocotrienols, Augustine S. H. Ong Analysis and Distribution of Vitamin E in
Vegetable Oils and Foods, Alan J. Sheppard, John L. Weihrauch, and Jean A.T.
Pennington Animals and Humans Absorption, Transport and Delivery to Tissues,
Maret G. Traber, William Cohn, and David P. R. Muller Interrelationships of
Vitamin E with Other Nutrients, Harold H. Draper Effects of ß-Carotene and
Related Caritenoids on Vitamin E, Shirley R. Blakely, Geraldine V. Mitchell,
Mamie Leah Young Jenkins, and Erich Grundel CHEMISTRY, BIOCHEMISTRY, AND CELL
BIOLOGY Chemical Reactions, Antioxidant Action, and Biomembranes Pulse
Radioysis as a Tool in Vitamin E Research, Wolf Bors, Manfred Saran, and
Christs Michel Peroxyl Radical Trapping Reactions of Alpha-Tocopherol in
Biomimetic Systems, Daniel C. Liebler Synthesis and Kinetic Study of
Antioxidant and Prooxidant Actions of Vitamin E Derivatives, Kazou Mukai
Rates and Products of Reactions of Vitamin E with Oxygen Radicals, Etsuo Niki
and Mitsuyoshi Matsuo Relative Importance of Vitamin E in Antiperoxidative
Defenses in Human Blood Plasma and Low-Density Lipoprotein (LDL), Balz B.
Frei and Bruce N. Ames Scavenging of Singlet Molecular Oxygen by Tocopherols,
Helmut Sies, Stephan Kaiser, Paulo Di Mascio, and Michael E. Murphy
Relationship Between Vitamin E and a More Electronegatively Charged LDL of
Human Plasma, Gabriele Bittolo-Bon, Giuseppe Cazzolato, and Pietro Avogaro
The Role of Vitamin E in Blood and Cellular Aging, Shiro Urano Pharamacology
Biokinetics of Vitamin E Using Deuterated Tocopherols, Graham W. Burton and
Keith U. Ingold Vitamin E Status of Exotic Animals Compared with Livestock
and Domestics, Ellen S. Dierenfeld and Maret G. Traber Alpha-Tocopherol and
Protein Kinase C Regulation of Intracellular Signaling, Angelo Manfredo Azzi,
Gianna Bartoli, Daniel Boscoboinik, Carmel Hensey, and Adam Szewczyk Vitamin
E Action in Modulating the Arachidonic Acid Cascade, David G. Cornwell and
Rao V. Panganamala The Safety of Oral Intake of Vitamin E: Data from Clinical
Studies from 1986 to 1991, Adrianne Bendich and Lawrence J. Machlin Reduction
in the Toxicity of Doxorubicin (Adriamycin) in the Heart by Vitamin E, José
Milei and Susana Llesuy PATHOPHYSIOLOGICAL CONDITIONS AND VITAMIN E
Metabolism and Aging Vitamin E and the Aging Process, Abraham Z. Reznick,
Bruce Rappaport, Sharon V. Landvik, Irene Simon-Schnass, and Lester Packer
Vitamin E and High-Altitude Exercise, Irene Simon-Schnass Significance of
Vitamin E for the Athlete, Lester Packer, Abraham Z. Reznick, Irene
Simon-Schnass, and Sharon V. Landvik Plasma Alpha-Tocopherol and Ubiquinone
and Their Relations to Muscle Function in Healthy Humans and in Cardiac
Diseases, Jan Karlsson, Bertil Diamant, Henning Theorell, Kurt Johansen, and
Karl Folkers Cancer Effects of Vitamin E on Oral Carcinogenesis and Oral
Cancer, Gerald Shklar and Joel L. Schwartz Epidemiology of Vitamin E:
Evidence for Anticancer Effects in Humans, Paul Knekt Antitumor Activity of
Tocotrienols, Kanki Komiyama and Masakazu Yamaoka Impact of Palm Oil on
Experimental Carcinogenesis, Charles E. Elson Immunity and Disease Resistance
Vitamin E and Immune Response, Simin Nikbin Meydani and Robert P. Tengerdy
MEDICAL APPLICATIONS Dermatology Vitamin E in Dermatological Therapy, Jurgen
Fuchs and Lester Packer Vitamin E and Coenzyme Q10 in Normal Human Skin and
in Basal Cell Epitheliomas, Luigi Rusciani, Giuseppina Petrelli, and Silvio
Lippa Vitamin E in Skin: Antioxidant and Prooxidant Balance, Eric Witt,
Valerian E. Kagan, and Lester Packer Neurology Vitamin E and Parkinson's
Disease, Lawrence I. Golbe and J. William Langston Vitamin E Therapy in
Neurological Diseases, Tuomas Westermarck, Erkki Antila, and Faik Atroshi
Effects of Palm Oil Vitamin E on Atherogenesis, Erkki Antila, Faik Atroshi,
and Tuomas Westermarck Vitamin E Deficiency and Neurological Disorders,
Ronald J. Sokol Effects of Vitamin E and Its Derivative on Posttraumatic
Epilepsy and Seizures, Akitane Mori, Isao Yokoi, and Hideaki Kabuto
Pediatrics Vitamin E in the Newborn, Sunil Sinha and Malcolm Chiswick FUTURE
PERSPECTIVES "
Packer\, Lester
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