A clear, engaging writing style, hundreds of full-color images, and new information throughout make Volpe's Neurology of the Newborn, 6th Edition, an indispensable resource for those who provide care for neonates with neurological conditions. World authority Dr. Joseph Volpe, along with Dr. Terrie E. Inder and other distinguished editors, continue the unparalleled clarity and guidance you've come to expect from the leading reference in the field - keeping you up to date with today's latest advances in diagnosis and management, as well as the many scientific and technological advances that are revolutionizing neonatal neurology.
Provides comprehensive coverage of neonatal neurology, solely written by the field's founding expert, Dr. Joseph Volpe - for a masterful, cohesive source of answers to any question that arises in your practice.
Focuses on clinical evaluation and management, while also examining the many scientific and technological advances that are revolutionizing neonatal neurology.
Organizes disease-focused chapters by affected body region for ease of reference.
Features a brand new, full-color design with hundreds of new figures, tables, algorithms, and micrographs.
Includes two entirely new chapters: Neurodevelopmental Follow-Up and Stroke in the Newborn; a new section on Neonatal Seizures; and an extensively expanded section on Hypoxic-Ischemia and Other Disorders.
Showcases the experience and knowledge of a new editorial team, led by Dr. Joseph Volpe and Dr. Terrie E. Inder, Chair of the Department of Pediatric Newborn Medicine at Brigham and Women's Hospital, all of whom bring a wealth of insight to this classic text.
Offers comprehensive updates from cover to cover to reflect all of the latest information regarding the development of the neural tube; prosencephalic development; congenital hydrocephalus; cerebellar hemorrhage; neuromuscular disorders and genetic testing; and much more.
Uses an improved organization to enhance navigation.
Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, Q&As, and references from the book on a variety of devices.
Recenzijas
"sets 'biblical standards' as the pinnacle of current medical knowledge on the neurology of the newborn"
"A highly recommendable book for now and for foreseeable future"
"This edition reaffirms the preeminent place is holds as the gold standard in this field. The addition of new editors and authors has broadened the scope and brought even greater credibility to the opinions expressed in areas that are controversial. This is a "must have" for every neonatal care provider and will probably find its way into many courtrooms where the etiology of perinatal brain injury is being adjudicated." Reviewed by Jay P. Goldsmith, MD (Tulane University School of Medicine) Doody's Score: 97, 5 Stars!
Unit I: Human Brain Development Overview
1. Neural Tube Development and Defects
2. Prosencephalic Development and Defects
3. Congenital Hydrocephalus
4. Cerebellar Development and Defects
5. Neuronal Proliferative Events and Defects
6. Neuronal Migrational Events and Defects
7. Organizational Events and Defects
8. Myelination Events and Defects
Unit II: Neurological Evaluation
Overview
9. Neurological Examination: Normal and Abnormal Features
10. Specialized Neurological Studies
11. Neurodevelopmental Followup
Unit III: Neonatal Seizures
Overview
12. Neonatal Seizures
Unit IV: Hypoxic-ischemic and Related Disorders
Overview
13. Pathophysiology General Principles
14. Encephalopathy of the Preterm - Neuropathology
15. Encephalopathy of the Preterm - Pathophysiology
16. Encephalopathy of the Preterm - Clinical - Neurological Features,
Diagnosis, Imaging, Prognosis, Therapy
17. Intrauterine, Intrapartum Assessments in the Term Infant
18. Hypoxic Ischemic Injury in the Term Infant - Neuropathology
19. Hypoxic Ischemic Injury in the Term Infant - Pathophysiology
20. Hypoxic Ischemic Injury in the Term Infant - Clinical - Neurological
Features, Diagnosis, Imaging, Prognosis, Therapy
21. Stroke in the Newborn
Unit V: Intracranial Hemorrhage
Overview
22. Intracranial/Hemorrhage - Supratentorial (Subdural, Subarachnoid,
Intraventricular (Term Infant), Miscellaneous
23. Intracranial Hemorrhage Infratentorial/Cerebellar
24. Preterm IVH/Posthemorrhagic Hydrocephalus
Unit VI: Metabolic Encephalopathies
Overview
25. Glucose
26. Bilirubin
27. Amino acids
28. Organic acids
Unit VII: Degenerative Disorders
29. Degenerative Disorders of the Newborn
Unit VIII: Neuromuscular Disorders
Overview
30. Evaluation, Specialized Studies
31. Arthrogryposis Multiplex Congenita
32. Levels Above Lower Motor Neuron to Neuromuscular Junction
33. Muscle Involvement and Restricted Disorders
Unit IX: Intracranial Infections
Overview
34. Viral, Protozoan and Related Intracranial Infections
35. Bacterial and Fungal Intracranial Infections
Unit X: Perinatal Trauma
36. Injuries of Extracranial, Cranial, Intracranial, Spinal Cord and
Peripheral Nervous System Structures
Unit XI: Intracranial Mass Lesions
37. Brain Tumors and Vein of Galen Malformations
Unit XII: Drugs and the Developing Nervous System
Overview
38. Passive Addiction and Teratogenic Effects
Joseph Volpe is generally considered to have founded the field of neonatal neurology. Dr. Inder is a dual-boarded neonatologist and child neurologist and is the current Chair of the Department of Pediatric Newborn Medicine. A native of New Zealand, she previously worked at the University of Melbourne, and Washington University in St. Louis before joining Brigham and Women's Hospital in 2013. She has a passion for improving long-term outcomes of high-risk infants including premature infants and at-risk term born infants. Dr. Inder is the Mary Ellen Avery Professor of Pediatrics in the Field of Newborn Medicine at Harvard Medical School. Dr. Basil T. Darras is Associate Neurologist-in-Chief and Chief of the Division of Clinical Neurology at Boston Children's Hospital, and the Joseph J. Volpe Professor of Neurology at Harvard Medical School. Dr. Darras is a pediatric neurologist with advanced training and certification in human genetics and neuromuscular medicine. At Boston Children's he serves as Director of the Neuromuscular Program, which includes one of the oldest and most active muscular dystrophy clinics in the country and where he specializes in the care of children with neuromuscular conditions originating from inherited or acquired conditions of the motor unit. He has published over 140 original reports in peer-reviewed journals and over 70 chapters, reviews and editorials; his major publications and specific research interests have focused on the molecular genetics, diagnostics, and therapeutics of Duchenne and Becker muscular dystrophies and spinal muscular atrophy, and on defining the indications for new diagnostic methodologies in the evaluation of children with pediatric neuromuscular diseases. Basic research, carried out in collaboration with scientists in the research laboratories of Boston Children's and other institutions, focuses on the description of novel mutations in patients with neuromuscular diseases and the application of new technologies to explore the pathogenesis and treatment of congenital myopathies and muscular dystrophies. Dr. Darras is site PI for the consortium conducting Pediatric Neuromuscular Clinical Research in Spinal Muscular Atrophy, and site PI/PD for the NeuroNEXT NINDS Program. He is currently involved in multiple clinical trials of novel genetic interventions for the treatment of spinal muscular atrophy and Duchenne muscular dystrophy. Linda de Vries is a neonatologist and pediatric neurologist, and obtained her PhD degree in Utrecht (1987). Since 1989, she has worked in the department of Neonatology in the University Medical Center Utrecht, where she is a professor in Neonatal Neurology. Her research focuses on prediction of neurodevelopmental outcome in high risk preterm and full-term newborns, using neurophysiology and neuro-imaging methods. These at risk children are also seen by her in the follow-up clinic until early childhood. She has a special interest in neonatal stroke and brain plasticity. Her work has been published in >400 publications.
